| Reaction Details |
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 | Report a problem with these data |
| Target | Aryl hydrocarbon receptor |
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| Ligand | BDBM50541261 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1984021 (CHEMBL4617427) |
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| EC50 | 0.260000±n/a nM |
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| Citation |  Wu, H; Liu, B; Yang, K; Winston-McPherson, GN; Leisten, ED; Vezina, CM; Ricke, WA; Peterson, RE; Tang, W Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aryl hydrocarbon receptor |
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| Name: | Aryl hydrocarbon receptor |
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| Synonyms: | AHR | AHR_HUMAN | BHLHE76 | Class E basic helix-loop-helix protein 76 | aryl hydrocarbon receptor precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96143.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1503828 |
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| Residue: | 848 |
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| Sequence: | MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQ
ALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP
SQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQ
GKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC
DAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRW
TWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPF
PAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAP
FENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLY
SIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQ
QQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFV
PFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYP
MGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQH
THVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFP
DLTSSGFL
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| BDBM50541261 |
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| n/a |
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| Name | BDBM50541261 |
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| Synonyms: | CHEMBL4646273 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14N2O |
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| Mol. Mass. | 298.338 |
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| SMILES | Cn1c2ccccc2c2cc3[nH]c4ccccc4c3c(C=O)c12 |
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| Structure | 
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