| Reaction Details |
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 | Report a problem with these data |
| Target | Protein FosB |
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| Ligand | BDBM50544071 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1991494 (CHEMBL4625229) |
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| IC50 | >100000±n/a nM |
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| Citation |  Li, Y; Liu, Z; Aglyamova, G; Chen, J; Chen, H; Bhandari, M; White, MA; Rudenko, G; Zhou, J Discovery of phenanthridine analogues as novel chemical probes disrupting the binding of DNA to ?FosB homodimers and ?FosB/JunD heterodimers. Bioorg Med Chem Lett30:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein FosB |
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| Name: | Protein FosB |
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| Synonyms: | FOSB | FOSB_HUMAN | G0/G1 switch regulatory protein 3 | G0S3 | Protein fosB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35915.32 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_119914 |
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| Residue: | 338 |
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| Sequence: | MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTA
ITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGS
GGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELT
DRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRD
LPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSY
TSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL
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| BDBM50544071 |
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| n/a |
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| Name | BDBM50544071 |
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| Synonyms: | CHEMBL4648025 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N2O4 |
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| Mol. Mass. | 394.4635 |
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| SMILES | COc1cc(OC)c2c(nc3c(OC)cccc3c2c1)C1CCN(CC1)C(C)=O |
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| Structure | 
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