| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon receptor |
|---|
| Ligand | BDBM50104074 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_72866 (CHEMBL683962) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Ling, A; Hong, Y; Gonzalez, J; Gregor, V; Polinsky, A; Kuki, A; Shi, S; Teston, K; Murphy, D; Porter, J; Kiel, D; Lakis, J; Anderes, K; May, J; Knudsen, LB; Lau, J Identification of alkylidene hydrazides as glucagon receptor antagonists. J Med Chem44:3141-9 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon receptor |
|---|
| Name: | Glucagon receptor |
|---|
| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54026.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P47871 |
|---|
| Residue: | 477 |
|---|
| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
|
|
|
|---|
| BDBM50104074 |
|---|
| n/a |
|---|
| Name | BDBM50104074 |
|---|
| Synonyms: | 4-Hydroxy-3-methoxy-benzoic acid (3-hydroxy-4-methoxy-benzylidene)-hydrazide | CHEMBL106738 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H16N2O5 |
|---|
| Mol. Mass. | 316.3086 |
|---|
| SMILES | COc1ccc(\C=N\NC(=O)c2ccc(O)c(OC)c2)cc1O |
|---|
| Structure | 
|
|---|
Search and Browse
