| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon receptor |
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| Ligand | BDBM50104098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72866 (CHEMBL683962) |
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| IC50 | >100000±n/a nM |
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| Citation |  Ling, A; Hong, Y; Gonzalez, J; Gregor, V; Polinsky, A; Kuki, A; Shi, S; Teston, K; Murphy, D; Porter, J; Kiel, D; Lakis, J; Anderes, K; May, J; Knudsen, LB; Lau, J Identification of alkylidene hydrazides as glucagon receptor antagonists. J Med Chem44:3141-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon receptor |
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| Name: | Glucagon receptor |
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| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54026.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47871 |
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| Residue: | 477 |
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| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
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| BDBM50104098 |
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| n/a |
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| Name | BDBM50104098 |
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| Synonyms: | 5-Hydroxy-1H-indole-2-carboxylic acid (4-hydroxy-naphthalen-1-ylmethylene)-hydrazide | CHEMBL108177 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15N3O3 |
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| Mol. Mass. | 345.3514 |
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| SMILES | Oc1ccc2[nH]c(cc2c1)C(=O)N\N=C\c1ccc(O)c2ccccc12 |
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| Structure | 
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