| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM50104694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_214524 (CHEMBL819516) |
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| IC50 | 11600±n/a nM |
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| Citation |  Sodeoka, M; Sampe, R; Kojima, S; Baba, Y; Usui, T; Ueda, K; Osada, H Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition. J Med Chem44:3216-22 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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| BDBM50104694 |
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| n/a |
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| Name | BDBM50104694 |
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| Synonyms: | (R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2(5H)-one | (R)-5-Ethyl-3-hexadecanoyl-4-methyl-5H-furan-2-oneo | 3-Hexadecanoyl-4-hydroxy-5-hydroxymethyl-5H-furan-2-one | CHEMBL108441 | RK-682 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H36O5 |
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| Mol. Mass. | 368.5075 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)c1c(O)oc(CO)c1O |
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| Structure | 
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