| Reaction Details |
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 | Report a problem with these data |
| Target | Urokinase plasminogen activator surface receptor |
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| Ligand | BDBM50549789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2025815 (CHEMBL4679628) |
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| IC50 | 2200±n/a nM |
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| Citation |  Bum-Erdene, K; Liu, D; Xu, D; Ghozayel, MK; Meroueh, SO Design and Synthesis of Fragment Derivatives with a Unique Inhibition Mechanism of the uPAR·uPA Interaction. ACS Med Chem Lett12:60-66 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Urokinase plasminogen activator surface receptor |
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| Name: | Urokinase plasminogen activator surface receptor |
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| Synonyms: | CD_antigen=CD87 | MO3 | Monocyte activation antigen Mo3 | PLAUR | U-PAR | UPAR | UPAR_HUMAN | Urokinase plasminogen activator surface receptor | Urokinase receptor (uPAR) | Urokinase-type plasminogen activator/surface receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 36979.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03405 |
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| Residue: | 335 |
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| Sequence: | MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEL
ELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISC
GSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNG
FHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGP
MNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDV
QYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
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| BDBM50549789 |
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| n/a |
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| Name | BDBM50549789 |
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| Synonyms: | CHEMBL4752534 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22N2O3S |
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| Mol. Mass. | 430.519 |
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| SMILES | COc1ccc(cc1)-c1cc(C(=O)N2CCOCC2)c2cccc(-c3cccs3)c2n1 |
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| Structure | 
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