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TargetNeuropeptide Y receptor type 1
LigandBDBM50109179
Substrate/Competitorn/a
Meas. Tech.ChEBML_143825
Ki 2.7±n/a nM
Citation Poindexter GSBruce MALeBoulluec KLMonkovic IMartin SWParker EMIben LGMcGovern RTOrtiz AAStanley JAMattson GKKozlowski MArcuri MAntal-Zimanyi I Dihydropyridine neuropeptide Y Y(1) receptor antagonists. Bioorg Med Chem Lett 12:379-82 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Neuropeptide Y receptor type 1
Name:Neuropeptide Y receptor type 1
Synonyms:NPY-Y1 | NPY1-R | neuropeptide Y receptor Y1
Type:Enzyme Catalytic Domain
Mol. Mass.:44399.07
Organism:Homo sapiens (Human)
Description:NPY-Y1 NPY1R HUMAN::P25929
Residue:384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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  Blast E-value cutoff:
BDBM50109179
n/a
NameBDBM50109179
Synonyms:4-[3-(3-{3-[4-(3-Hydroxy-phenyl)-piperidin-1-yl]-propyl}-ureido)-phenyl]-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester | CHEMBL126618
TypeSmall organic molecule
Emp. Form.C32H40N4O6
Mol. Mass.576.6832
SMILESCOC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1cccc(NC(=O)NCCCN2CCC(CC2)c2cccc(O)c2)c1 |c:13,t:10|
Structure
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