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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vasopressin V1a receptor | ||
| Ligand | BDBM50114034 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_214561 (CHEMBL820178) | ||
| Ki | 9.69±n/a nM | ||
| Citation |  Kakefuda, A; Suzuki, T; Tobe, T; Tsukada, J; Tahara, A; Sakamoto, S; Tsukamoto, S Synthesis and pharmacological evaluation of 5-(4-biphenyl)-3-methyl-4-phenyl-1,2,4-triazole derivatives as a novel class of selective antagonists for the human vasopressin V(1A) receptor. J Med Chem45:2589-98 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vasopressin V1a receptor | |||
| Name: | Vasopressin V1a receptor | ||
| Synonyms: | Avpr1a | V1AR_RAT | VASOPRESSIN V1A | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 47674.81 | ||
| Organism: | RAT | ||
| Description: | VASOPRESSIN V1A AVPR1A RAT::P30560 | ||
| Residue: | 424 | ||
| Sequence: |
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| BDBM50114034 | |||
| n/a | |||
| Name | BDBM50114034 | ||
| Synonyms: | 1'-{6-[2-(3-Biphenyl-4-yl-5-methyl-[1,2,4]triazol-4-yl)-phenoxy]-hexyl}-[1,4']bipiperidinyl | CHEMBL86949 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C37H47N5O | ||
| Mol. Mass. | 577.802 | ||
| SMILES | Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1OCCCCCCN1CCC(CC1)N1CCCCC1 |(6.93,-1.75,;5.55,-2.43,;4.25,-1.61,;3.06,-2.57,;3.62,-4.01,;2.78,-5.3,;1.24,-5.23,;.4,-6.52,;1.1,-7.87,;2.64,-7.96,;3.48,-6.68,;.26,-9.17,;.96,-10.54,;.12,-11.84,;-1.42,-11.74,;-2.11,-10.37,;-1.28,-9.08,;5.16,-3.93,;6.17,-5.07,;5.68,-6.54,;6.69,-7.68,;8.2,-7.38,;8.69,-5.91,;7.66,-4.77,;8.15,-3.3,;9.52,-2.62,;10.8,-3.48,;12.18,-2.78,;13.46,-3.65,;14.84,-2.95,;16.13,-3.81,;17.5,-3.13,;19.04,-3.27,;19.93,-2.04,;19.3,-.63,;17.76,-.47,;16.87,-1.73,;20.09,.67,;19.39,2.01,;20.21,3.3,;21.73,3.24,;22.45,1.91,;21.63,.61,)| | ||
| Structure | 
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