| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50116070 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_123920 |
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| IC50 | >150000±n/a nM |
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| Citation |  Sciotti, RJ; Pliushchev, M; Wiedeman, PE; Balli, D; Flamm, R; Nilius, AM; Marsh, K; Stolarik, D; Jolly, R; Ulrich, R; Djuric, SW The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class. Bioorg Med Chem Lett12:2121-3 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_RAT | Amine oxidase (flavin-containing) B | Amine oxidase [flavin-containing] B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase B (rMAO-B) | Monoamine oxidase type B (MAOB) | Monoamine oxidase-B (MAO-B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 58469.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P19643 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWR
TMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQ
TGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVY
YKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEER
LRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGK
IFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNT
FLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
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| BDBM50116070 |
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| n/a |
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| Name | BDBM50116070 |
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| Synonyms: | CHEMBL69609 | N-((S)-3-{4-[(Z)-2-Bromo-2-(3-hydroxymethyl-phenyl)-vinyl]-3-fluoro-phenyl}-2-oxo-oxazolidin-5-ylmethyl)-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20BrFN2O4 |
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| Mol. Mass. | 463.297 |
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| SMILES | CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(\C=C(/Br)c2cccc(CO)c2)c(F)c1 |
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| Structure | 
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