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TargetMycothiol S-conjugate amidase
LigandBDBM50117081
Substrate/Competitorn/a
Meas. Tech.ChEBML_140808
IC50 100000±n/a nM
Citation Nicholas GMEckman LLRay SHughes ROPfefferkorn JABarluenga SNicolaou KCBewley CA Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorg Med Chem Lett 12:2487-90 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mycothiol S-conjugate amidase
Name:Mycothiol S-conjugate amidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:32719.79
Organism:Mycobacterium tuberculosis
Description:ChEMBL_626858
Residue:288
Sequence:
MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGR
IAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLPDDCFARVPLEVSTEALVRVV
REFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAGDFCRFPDAGEPWTVSKLYYVHGF
LRERMQMLQDEFARHGQRGPFEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHA
TQIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP
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  Blast E-value cutoff:
BDBM50117081
n/a
NameBDBM50117081
Synonyms:(S)-7,9-Dibromo-8-methoxy-1-oxa-2-aza-spiro[4.5]deca-2,6,8-triene-3-carboxylic acid [2-(2-amino-3H-imidazol-4-yl)-ethyl]-amide | CHEMBL82521
TypeSmall organic molecule
Emp. Form.C15H17Br2N5O3
Mol. Mass.475.135
SMILESCOC1=C(Br)C[C@@]2(CC(=NO2)C(=O)NCCc2cnc(N)[nH]2)C=C1Br |c:2,8,24|
Structure
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