| Reaction Details |
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 | Report a problem with these data |
| Target | Mycothiol S-conjugate amidase |
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| Ligand | BDBM50117081 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_140808 |
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| IC50 | 100000±n/a nM |
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| Citation |  Nicholas, GM; Eckman, LL; Ray, S; Hughes, RO; Pfefferkorn, JA; Barluenga, S; Nicolaou, KC; Bewley, CA Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorg Med Chem Lett12:2487-90 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mycothiol S-conjugate amidase |
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| Name: | Mycothiol S-conjugate amidase |
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| Synonyms: | MCA_MYCTU | mca |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32719.79 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | ChEMBL_626858 |
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| Residue: | 288 |
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| Sequence: | MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGR
IAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLPDDCFARVPLEVSTEALVRVV
REFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAGDFCRFPDAGEPWTVSKLYYVHGF
LRERMQMLQDEFARHGQRGPFEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHA
TQIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP
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| BDBM50117081 |
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| n/a |
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| Name | BDBM50117081 |
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| Synonyms: | (S)-7,9-Dibromo-8-methoxy-1-oxa-2-aza-spiro[4.5]deca-2,6,8-triene-3-carboxylic acid [2-(2-amino-3H-imidazol-4-yl)-ethyl]-amide | CHEMBL82521 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17Br2N5O3 |
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| Mol. Mass. | 475.135 |
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| SMILES | COC1=C(Br)C[C@@]2(CC(=NO2)C(=O)NCCc2cnc(N)[nH]2)C=C1Br |c:2,8,24| |
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| Structure | 
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