| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50561628 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2075553 (CHEMBL4731087) |
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| Ki | 0.022000±n/a nM |
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| Citation |  Ghosh, AK; Grillo, A; Raghavaiah, J; Kovela, S; Johnson, ME; Kneller, DW; Wang, YF; Hattori, SI; Higashi-Kuwata, N; Weber, IT; Mitsuya, H Design, Synthesis, and X-ray Studies of Potent HIV-1 Protease Inhibitors with P2-Carboxamide Functionalities. ACS Med Chem Lett11:1965-1972 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50561628 |
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| n/a |
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| Name | BDBM50561628 |
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| Synonyms: | CHEMBL4800615 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H41N3O6S |
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| Mol. Mass. | 571.728 |
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| SMILES | [H][C@@]12CO[C@]3([H])OCC(CC13)[C@@H]2CC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(N)cc1 |r,TLB:2:1:7.6.4:9,THB:12:11:7.6.4:9,3:4:11.1:9| |
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| Structure | 
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