| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50126765 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145820 (CHEMBL753681) |
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| Ki | 15±n/a nM |
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| Citation |  Holzgrabe, U; Brandt, W Mechanism of action of the diazabicyclononanone-type kappa-agonists. J Med Chem46:1383-9 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42692.90 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P34975 |
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| Residue: | 380 |
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| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
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| BDBM50126765 |
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| n/a |
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| Name | BDBM50126765 |
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| Synonyms: | 3,7-Dimethyl-2,4-di-pyridin-2-yl-3,7-diaza-bicyclo[3.3.1]nonan-9-one | CHEMBL287392 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N4O |
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| Mol. Mass. | 322.4042 |
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| SMILES | CN1CC2C(N(C)C(C(C1)C2=O)c1ccccn1)c1ccccn1 |TLB:18:4:10:1.2.9,11:10:5.7.4:1.2.9,6:5:10:1.2.9,THB:12:7:10:1.2.9,0:1:10:5.7.4| |
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| Structure | 
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