| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bcl2-associated agonist of cell death |
|---|
| Ligand | BDBM50568339 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2105122 (CHEMBL4813625) |
|---|
| Ki | 1080±n/a nM |
|---|
| Citation |  Niu, Q; Deng, H; Zhang, Z; Xu, Q; Luan, S; Huang, M; Liu, D; Zhao, L Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett47:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bcl2-associated agonist of cell death |
|---|
| Name: | Bcl2-associated agonist of cell death |
|---|
| Synonyms: | BAD | BAD_HUMAN | BBC6 | BCL2L8 | Bcl-2-binding component 6 | Bcl-2-like protein 8 | Bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8 | Bcl2-antagonist of cell death (BAD) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 18393.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_478760 |
|---|
| Residue: | 168 |
|---|
| Sequence: | MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSH
HGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDE
FVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
|
|
|
|---|
| BDBM50568339 |
|---|
| n/a |
|---|
| Name | BDBM50568339 |
|---|
| Synonyms: | CHEMBL4876147 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H22F3NO2 |
|---|
| Mol. Mass. | 521.5285 |
|---|
| SMILES | OC(=O)c1ccccc1-c1cccc2n(Cc3cccc4ccccc34)cc(-c3cccc(c3)C(F)(F)F)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
