Found 1796 hits with Last Name = 'deng' and Initial = 'h' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM161571
(US9108983, Example 386 | US9108983, Example 449)Show SMILES Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1 Show InChI InChI=1S/C41H41ClN6O4/c1-26-36(41(51)48(31-10-12-34(49)13-11-31)38-21-32(23-43)44(3)27(38)2)22-39(45(26)4)37-20-30(42)9-14-35(37)40(50)47-24-29-8-6-5-7-28(29)19-33(47)25-46-15-17-52-18-16-46/h5-14,20-22,33,49H,15-19,24-25H2,1-4H3/t33-/m0/s1 | PDB
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| Article
PubMed
| 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Mus musculus (Mouse)) | BDBM50172545
((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...)Show InChI InChI=1S/C22H23IN2O/c1-24-13-7-6-8-16(24)14-25-15-19(17-9-3-5-12-21(17)25)22(26)18-10-2-4-11-20(18)23/h2-5,9-12,15-16H,6-8,13-14H2,1H3 | PDB
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| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Diacylglycerol lipase-alpha
(Mus musculus) | BDBM50519345
(CHEMBL4447844)Show SMILES Cc1ccc(cc1)-c1cnc2nc(oc2c1)C(=O)CCCCCc1ccccc1 Show InChI InChI=1S/C25H24N2O2/c1-18-12-14-20(15-13-18)21-16-23-24(26-17-21)27-25(29-23)22(28)11-7-3-6-10-19-8-4-2-5-9-19/h2,4-5,8-9,12-17H,3,6-7,10-11H2,1H3 | UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| Article
PubMed
| 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate subs... |
J Med Chem 62: 7910-7922 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00686
BindingDB Entry DOI: 10.7270/Q2GQ724G |
More data for this
Ligand-Target Pair | |
Diacylglycerol lipase-alpha
(Mus musculus) | BDBM50211257
(CHEMBL3895863 | US10583137, Compound 14)Show SMILES OC(c1cnn(n1)C(=O)N1C[C@@H](CC[C@@H]1Cc1ccccc1)OCC#C)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C31H28F2N4O3/c1-2-18-40-28-17-16-27(19-22-6-4-3-5-7-22)36(21-28)30(38)37-34-20-29(35-37)31(39,23-8-12-25(32)13-9-23)24-10-14-26(33)15-11-24/h1,3-15,20,27-28,39H,16-19,21H2/t27-,28-/m1/s1 | UniProtKB/SwissProt
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| 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate subs... |
J Med Chem 62: 7910-7922 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00686
BindingDB Entry DOI: 10.7270/Q2GQ724G |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM161571
(US9108983, Example 386 | US9108983, Example 449)Show SMILES Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1 Show InChI InChI=1S/C41H41ClN6O4/c1-26-36(41(51)48(31-10-12-34(49)13-11-31)38-21-32(23-43)44(3)27(38)2)22-39(45(26)4)37-20-30(42)9-14-35(37)40(50)47-24-29-8-6-5-7-28(29)19-33(47)25-46-15-17-52-18-16-46/h5-14,20-22,33,49H,15-19,24-25H2,1-4H3/t33-/m0/s1 | PDB
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| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM161571
(US9108983, Example 386 | US9108983, Example 449)Show SMILES Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1 Show InChI InChI=1S/C41H41ClN6O4/c1-26-36(41(51)48(31-10-12-34(49)13-11-31)38-21-32(23-43)44(3)27(38)2)22-39(45(26)4)37-20-30(42)9-14-35(37)40(50)47-24-29-8-6-5-7-28(29)19-33(47)25-46-15-17-52-18-16-46/h5-14,20-22,33,49H,15-19,24-25H2,1-4H3/t33-/m0/s1 | PDB
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| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50590323
(CHEMBL5173522)Show SMILES [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)NC(=O)[C@@H]1Cc2cc(Br)c(OCc3ccc(cc3)-c3ccccc3)c(Br)c2CN1Cc1ccc(cc1)C#N |r| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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| PC cid
PC sid
UniChem
| Article
PubMed
| 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Diacylglycerol lipase-alpha
(Mus musculus) | BDBM50211236
(CHEMBL2144065)Show SMILES O=C(N1CCCCC1Cc1ccccc1)n1cc(nn1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C27H26N4O/c32-27(30-18-8-7-13-25(30)19-21-9-3-1-4-10-21)31-20-26(28-29-31)24-16-14-23(15-17-24)22-11-5-2-6-12-22/h1-6,9-12,14-17,20,25H,7-8,13,18-19H2 | UniProtKB/SwissProt
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| 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate subs... |
J Med Chem 62: 7910-7922 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00686
BindingDB Entry DOI: 10.7270/Q2GQ724G |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50590323
(CHEMBL5173522)Show SMILES [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)NC(=O)[C@@H]1Cc2cc(Br)c(OCc3ccc(cc3)-c3ccccc3)c(Br)c2CN1Cc1ccc(cc1)C#N |r| | PDB
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| PC cid
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| 0.450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM161571
(US9108983, Example 386 | US9108983, Example 449)Show SMILES Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1 Show InChI InChI=1S/C41H41ClN6O4/c1-26-36(41(51)48(31-10-12-34(49)13-11-31)38-21-32(23-43)44(3)27(38)2)22-39(45(26)4)37-20-30(42)9-14-35(37)40(50)47-24-29-8-6-5-7-28(29)19-33(47)25-46-15-17-52-18-16-46/h5-14,20-22,33,49H,15-19,24-25H2,1-4H3/t33-/m0/s1 | PDB
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| 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50266959
(CHEMBL4085804)Show SMILES CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(O)CC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C53H59ClF4N6O7S4/c1-35(2)64-36(3)52(73(4,66)67)50(51(64)37-10-12-39(54)13-11-37)38-30-40(55)32-44(31-38)63-28-26-62(27-29-63)43-16-14-41(15-17-43)60-75(70,71)47-18-19-48(49(33-47)74(68,69)53(56,57)58)59-42(34-72-46-8-6-5-7-9-46)20-23-61-24-21-45(65)22-25-61/h5-19,30-33,35,42,45,59-60,65H,20-29,34H2,1-4H3/t42-/m1/s1 | PDB
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| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50172553
(CHEMBL68641 | [1-(1-Methyl-piperidin-2-ylmethyl)-1...)Show SMILES CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccccc12 Show InChI InChI=1S/C26H26N2O/c1-27-16-7-6-11-20(27)17-28-18-24(22-13-4-5-15-25(22)28)26(29)23-14-8-10-19-9-2-3-12-21(19)23/h2-5,8-10,12-15,18,20H,6-7,11,16-17H2,1H3 | PDB
Reactome pathway
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| Article
PubMed
| 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50568342
(CHEMBL4851522)Show SMILES [H][C@@]12CC[C@@]1([H])[C@@H](OC)\C=C\C[C@H](C)[C@@H](C)S(=O)(=O)CNc1ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CCN(C2)c3c1 |r,t:10| | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Bcl-2-like protein 1
(Homo sapiens (Human)) | BDBM50162774
(ABT-199 | US11420968, Example ABT-199 | Venetoclax)Show SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1 |c:57| Show InChI InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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KEGG
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| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Bc1-xL (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Bcl-2-like protein 1
(Homo sapiens (Human)) | BDBM50590322
(PELCITOCLAX | Pelcitoclax)Show SMILES CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(CC3)C(=O)OCCCP(O)(O)=O)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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| <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Bcl-2-like protein 1
(Homo sapiens (Human)) | BDBM50266959
(CHEMBL4085804)Show SMILES CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(O)CC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O |r| Show InChI InChI=1S/C53H59ClF4N6O7S4/c1-35(2)64-36(3)52(73(4,66)67)50(51(64)37-10-12-39(54)13-11-37)38-30-40(55)32-44(31-38)63-28-26-62(27-29-63)43-16-14-41(15-17-43)60-75(70,71)47-18-19-48(49(33-47)74(68,69)53(56,57)58)59-42(34-72-46-8-6-5-7-9-46)20-23-61-24-21-45(65)22-25-61/h5-19,30-33,35,42,45,59-60,65H,20-29,34H2,1-4H3/t42-/m1/s1 | PDB
MMDB
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Reactome pathway
KEGG
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| <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50590322
(PELCITOCLAX | Pelcitoclax)Show SMILES CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(CC3)C(=O)OCCCP(O)(O)=O)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O | PDB
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| <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50162774
(ABT-199 | US11420968, Example ABT-199 | Venetoclax)Show SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1 |c:57| Show InChI InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54) | PDB
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| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM177786
(US9120791, Example 1 | US9120791, Example 38 | US9...)Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C43H42N4O6/c48-34-15-13-32(14-16-34)47(31-10-2-1-3-11-31)43(50)37-23-39(45-17-7-6-12-38(37)45)35-24-40-41(53-28-52-40)25-36(35)42(49)46-26-30-9-5-4-8-29(30)22-33(46)27-44-18-20-51-21-19-44/h1-5,8-11,13-16,23-25,33,48H,6-7,12,17-22,26-28H2/t33-/m0/s1 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Mus musculus (Mouse)) | BDBM50172545
((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...)Show InChI InChI=1S/C22H23IN2O/c1-24-13-7-6-8-16(24)14-25-15-19(17-9-3-5-12-21(17)25)22(26)18-10-2-4-11-20(18)23/h2-5,9-12,15-16H,6-8,13-14H2,1H3 | PDB
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| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [3H]SR-141,716A |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Mus musculus (Mouse)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [131I]-(R)-8 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50172553
(CHEMBL68641 | [1-(1-Methyl-piperidin-2-ylmethyl)-1...)Show SMILES CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccccc12 Show InChI InChI=1S/C26H26N2O/c1-27-16-7-6-11-20(27)17-28-18-24(22-13-4-5-15-25(22)28)26(29)23-14-8-10-19-9-2-3-12-21(19)23/h2-5,8-10,12-15,18,20H,6-7,11,16-17H2,1H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM177786
(US9120791, Example 1 | US9120791, Example 38 | US9...)Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C43H42N4O6/c48-34-15-13-32(14-16-34)47(31-10-2-1-3-11-31)43(50)37-23-39(45-17-7-6-12-38(37)45)35-24-40-41(53-28-52-40)25-36(35)42(49)46-26-30-9-5-4-8-29(30)22-33(46)27-44-18-20-51-21-19-44/h1-5,8-11,13-16,23-25,33,48H,6-7,12,17-22,26-28H2/t33-/m0/s1 | PDB
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Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50172545
((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...)Show InChI InChI=1S/C22H23IN2O/c1-24-13-7-6-8-16(24)14-25-15-19(17-9-3-5-12-21(17)25)22(26)18-10-2-4-11-20(18)23/h2-5,9-12,15-16H,6-8,13-14H2,1H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50172545
((2-Iodo-phenyl)-[1-((S)-1-methyl-piperidin-2-ylmet...)Show InChI InChI=1S/C22H23IN2O/c1-24-13-7-6-8-16(24)14-25-15-19(17-9-3-5-12-21(17)25)22(26)18-10-2-4-11-20(18)23/h2-5,9-12,15-16H,6-8,13-14H2,1H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50590324
(CHEMBL5201080)Show SMILES CCN(CC)C[C@@H](O)CNc1ccc(NC[C@H]2CO2)c2C(=O)c3ccccc3C(=O)c12 |r| | PDB
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Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM177786
(US9120791, Example 1 | US9120791, Example 38 | US9...)Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C43H42N4O6/c48-34-15-13-32(14-16-34)47(31-10-2-1-3-11-31)43(50)37-23-39(45-17-7-6-12-38(37)45)35-24-40-41(53-28-52-40)25-36(35)42(49)46-26-30-9-5-4-8-29(30)22-33(46)27-44-18-20-51-21-19-44/h1-5,8-11,13-16,23-25,33,48H,6-7,12,17-22,26-28H2/t33-/m0/s1 | PDB
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Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Non-lysosomal glucosylceramidase
(Homo sapiens (Human)) | BDBM50608552
(CHEMBL5269107) | Reactome pathway
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Citation and Details
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More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50174549
((4-Iodo-naphthalen-1-yl)-[1-(1-methyl-piperidin-2-...)Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(I)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C26H25IN2O/c1-28-15-7-6-8-18(28)16-29-17-23(21-11-4-5-12-25(21)29)26(30)22-13-14-24(27)20-10-3-2-9-19(20)22/h2-5,9-14,17-18H,6-8,15-16H2,1H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM177786
(US9120791, Example 1 | US9120791, Example 38 | US9...)Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccccc1 Show InChI InChI=1S/C43H42N4O6/c48-34-15-13-32(14-16-34)47(31-10-2-1-3-11-31)43(50)37-23-39(45-17-7-6-12-38(37)45)35-24-40-41(53-28-52-40)25-36(35)42(49)46-26-30-9-5-4-8-29(30)22-33(46)27-44-18-20-51-21-19-44/h1-5,8-11,13-16,23-25,33,48H,6-7,12,17-22,26-28H2/t33-/m0/s1 | PDB
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Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50174548
((2-Iodo-phenyl)-[2-methyl-1-(1-methyl-piperidin-2-...)Show InChI InChI=1S/C23H25IN2O/c1-16-22(23(27)18-10-3-5-12-20(18)24)19-11-4-6-13-21(19)26(16)15-17-9-7-8-14-25(17)2/h3-6,10-13,17H,7-9,14-15H2,1-2H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Non-lysosomal glucosylceramidase
(Homo sapiens (Human)) | BDBM50608553
(CHEMBL5291161) | Reactome pathway
KEGG
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Citation and Details
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More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50174547
(CHEMBL436120 | [6-Iodo-1-(1-methyl-piperidin-2-ylm...)Show SMILES CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccc(I)cc12 Show InChI InChI=1S/C26H25IN2O/c1-28-14-5-4-9-20(28)16-29-17-24(22-13-12-19(27)15-25(22)29)26(30)23-11-6-8-18-7-2-3-10-21(18)23/h2-3,6-8,10-13,15,17,20H,4-5,9,14,16H2,1H3 | PDB
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| 9.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50174549
((4-Iodo-naphthalen-1-yl)-[1-(1-methyl-piperidin-2-...)Show SMILES CN1CCCCC1Cn1cc(C(=O)c2ccc(I)c3ccccc23)c2ccccc12 Show InChI InChI=1S/C26H25IN2O/c1-28-15-7-6-8-18(28)16-29-17-23(21-11-4-5-12-25(21)29)26(30)22-13-14-24(27)20-10-3-2-9-19(20)22/h2-5,9-14,17-18H,6-8,15-16H2,1H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Diacylglycerol lipase-alpha
(Mus musculus) | BDBM50211265
(CHEMBL3954476)Show SMILES OC(c1cnn(n1)C(=O)N1CCCC[C@@H]1Cc1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C28H26F2N4O2/c29-23-13-9-21(10-14-23)28(36,22-11-15-24(30)16-12-22)26-19-31-34(32-26)27(35)33-17-5-4-8-25(33)18-20-6-2-1-3-7-20/h1-3,6-7,9-16,19,25,36H,4-5,8,17-18H2/t25-/m1/s1 | UniProtKB/SwissProt
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Leiden University
Curated by ChEMBL
| Assay Description
Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate subs... |
J Med Chem 62: 7910-7922 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00686
BindingDB Entry DOI: 10.7270/Q2GQ724G |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50174548
((2-Iodo-phenyl)-[2-methyl-1-(1-methyl-piperidin-2-...)Show InChI InChI=1S/C23H25IN2O/c1-16-22(23(27)18-10-3-5-12-20(18)24)19-11-4-6-13-21(19)26(16)15-17-9-7-8-14-25(17)2/h3-6,10-13,17H,7-9,14-15H2,1-2H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50162774
(ABT-199 | US11420968, Example ABT-199 | Venetoclax)Show SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1 |c:57| Show InChI InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54) | PDB
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Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50174547
(CHEMBL436120 | [6-Iodo-1-(1-methyl-piperidin-2-ylm...)Show SMILES CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccc(I)cc12 Show InChI InChI=1S/C26H25IN2O/c1-28-14-5-4-9-20(28)16-29-17-24(22-13-12-19(27)15-25(22)29)26(30)23-11-6-8-18-7-2-3-10-21(18)23/h2-3,6-8,10-13,15,17,20H,4-5,9,14,16H2,1H3 | PDB
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Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Mus musculus (Mouse)) | BDBM21281
((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...)Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1 | PDB
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| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse hippocampal membranes cannabinoid receptor 1 using [3H]SR-141,716A |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50568326
(CHEMBL4872671)Show SMILES OC(=O)c1ccccc1-c1cccc2n(CCOc3cccc4ccccc34)cc(-c3cccc(c3)C(F)(F)F)c12 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50174548
((2-Iodo-phenyl)-[2-methyl-1-(1-methyl-piperidin-2-...)Show InChI InChI=1S/C23H25IN2O/c1-16-22(23(27)18-10-3-5-12-20(18)24)19-11-4-6-13-21(19)26(16)15-17-9-7-8-14-25(17)2/h3-6,10-13,17H,7-9,14-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50174548
((2-Iodo-phenyl)-[2-methyl-1-(1-methyl-piperidin-2-...)Show InChI InChI=1S/C23H25IN2O/c1-16-22(23(27)18-10-3-5-12-20(18)24)19-11-4-6-13-21(19)26(16)15-17-9-7-8-14-25(17)2/h3-6,10-13,17H,7-9,14-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 2
(MOUSE) | BDBM50174548
((2-Iodo-phenyl)-[2-methyl-1-(1-methyl-piperidin-2-...)Show InChI InChI=1S/C23H25IN2O/c1-16-22(23(27)18-10-3-5-12-20(18)24)19-11-4-6-13-21(19)26(16)15-17-9-7-8-14-25(17)2/h3-6,10-13,17H,7-9,14-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards mouse spleen cannabinoid receptor 2 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Cannabinoid receptor 1
(Rattus norvegicus (rat)) | BDBM50174548
((2-Iodo-phenyl)-[2-methyl-1-(1-methyl-piperidin-2-...)Show InChI InChI=1S/C23H25IN2O/c1-16-22(23(27)18-10-3-5-12-20(18)24)19-11-4-6-13-21(19)26(16)15-17-9-7-8-14-25(17)2/h3-6,10-13,17H,7-9,14-15H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University
Curated by ChEMBL
| Assay Description
Binding affinity towards rat forebrain cannabinoid receptor 1 using [3H]CP-55940 |
J Med Chem 48: 6386-92 (2005)
Article DOI: 10.1021/jm050135l
BindingDB Entry DOI: 10.7270/Q21V5FQ7 |
More data for this
Ligand-Target Pair | |
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50162774
(ABT-199 | US11420968, Example ABT-199 | Venetoclax)Show SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)N(=O)=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1 |c:57| Show InChI InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114184
BindingDB Entry DOI: 10.7270/Q2M049DT |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50568336
(CHEMBL4870458)Show SMILES Cc1ccccc1-c1cn(Cc2cccc3ccccc23)c2cccc(-c3ccccc3C(O)=O)c12 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Bcl2-associated agonist of cell death
(Homo sapiens (Human)) | BDBM50568338
(CHEMBL4872320)Show SMILES OC(=O)c1ccccc1-c1cccc2n(Cc3cccc4ccccc34)cc(-c3cccc(Cl)c3)c12 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50568341
(CHEMBL4870837)Show SMILES OC(=O)c1ccccc1-c1cccc2n(Cc3cccc4ccccc34)cc(-c3ccccc3)c12 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50568332
(CHEMBL4856143)Show SMILES COc1ccccc1-c1cn(CCOc2cccc3ccccc23)c2cccc(-c3ccccc3C(O)=O)c12 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50568328
(CHEMBL4864929)Show SMILES Cc1ccccc1-c1cn(CCOc2cccc3ccccc23)c2cccc(-c3ccccc3C(O)=O)c12 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assay |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128215
BindingDB Entry DOI: 10.7270/Q2K35ZDS |
More data for this
Ligand-Target Pair | |
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