| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50569112 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2107603 (CHEMBL4816278) |
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| Ki | 57±n/a nM |
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| Citation |  Watanabe, H; Ishida, K; Yamamoto, M; Nakako, T; Horiguchi, M; Isobe, Y Identification of 2-fluoro-8-methyl-11-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-5H-dibenzo[b,e][1,4]diazepine with clozapine-like mixed activities at muscarinic acetylcholine, dopamine, and serotonin receptors. Bioorg Med Chem Lett40:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50569112 |
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| n/a |
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| Name | BDBM50569112 |
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| Synonyms: | CHEMBL4865663 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23N3 |
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| Mol. Mass. | 317.4274 |
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| SMILES | CN1CCC(=CC1)C1=Nc2cc(C)ccc2Nc2ccc(C)cc12 |c:4,t:8| |
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| Structure | 
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