| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 4 group A member 1 |
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| Ligand | BDBM50570057 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2111007 (CHEMBL4819857) |
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| Kd | 36±n/a nM |
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| Citation |  Tu, X; Chen, X; Zhang, D; Gao, M; Liang, J; Bao, G; Zhang, J; Peng, S; Zhang, X; Zeng, Z; Su, Y Optimization of novel oxidative DIMs as Nur77 modulators of the Nur77-Bcl-2 apoptotic pathway. Eur J Med Chem211:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 4 group A member 1 |
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| Name: | Nuclear receptor subfamily 4 group A member 1 |
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| Synonyms: | GFRP1 | HMR | NAK1 | NR4A1 | NR4A1_HUMAN | nuclear receptor subfamily 4, group A, member 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 64467.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_27894344 |
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| Residue: | 598 |
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| Sequence: | MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGY
TGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV
DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKA
SGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL
EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAK
YICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS
PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKW
AEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG
DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVA
AVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
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| BDBM50570057 |
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| n/a |
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| Name | BDBM50570057 |
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| Synonyms: | CHEMBL4857769 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20ClF3N2 |
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| Mol. Mass. | 452.899 |
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| SMILES | [Cl-].CCn1cc([C+](c2c[nH]c3ccccc23)c2ccc(cc2)C(F)(F)F)c2ccccc12 |
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| Structure | 
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