| Reaction Details |
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 | Report a problem with these data |
| Target | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Ligand | BDBM50221211 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_208264 (CHEMBL813224) |
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| IC50 | 12.2±n/a nM |
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| Citation |  Hotoda, H; Furukawa, M; Daigo, M; Murayama, K; Kaneko, M; Muramatsu, Y; Ishii, MM; Miyakoshi, S; Takatsu, T; Inukai, M; Kakuta, M; Abe, T; Harasaki, T; Fukuoka, T; Utsui, Y; Ohya, S Synthesis and antimycobacterial activity of capuramycin analogues. Part 1: substitution of the azepan-2-one moiety of capuramycin. Bioorg Med Chem Lett13:2829-32 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Name: | Phospho-N-acetylmuramoyl-pentapeptide-transferase |
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| Synonyms: | MRAY_ECOLI | Phospho-N-acetylmuramoyl-pentapeptide-transferase/UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | mraY | murX |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39889.38 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_1454117 |
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| Residue: | 360 |
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| Sequence: | MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRND
GPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKV
VRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLA
YFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVE
TLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
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| BDBM50221211 |
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| n/a |
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| Name | BDBM50221211 |
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| Synonyms: | CHEMBL97077 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N4O11 |
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| Mol. Mass. | 534.4727 |
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| SMILES | [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccccc1)C(N)=O |c:23| |
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| Structure | 
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