Found 160 hits with Last Name = 'furukawa' and Initial = 'm' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025312
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-(3-...)Show SMILES COc1cc2oc(cc(=O)c2c(O)c1OCCC(C)C)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C21H22O7/c1-11(2)6-7-27-21-18(26-3)10-17-19(20(21)25)15(24)9-16(28-17)12-4-5-13(22)14(23)8-12/h4-5,8-11,22-23,25H,6-7H2,1-3H3 | PDB
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| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025322
(6-Decyloxy-2-(3,4-dihydroxy-phenyl)-5-hydroxy-7-me...)Show SMILES CCCCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C26H32O7/c1-3-4-5-6-7-8-9-10-13-32-26-23(31-2)16-22-24(25(26)30)20(29)15-21(33-22)17-11-12-18(27)19(28)14-17/h11-12,14-16,27-28,30H,3-10,13H2,1-2H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025315
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-oct...)Show SMILES CCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C24H28O7/c1-3-4-5-6-7-8-11-30-24-21(29-2)14-20-22(23(24)28)18(27)13-19(31-20)15-9-10-16(25)17(26)12-15/h9-10,12-14,25-26,28H,3-8,11H2,1-2H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221211
(CHEMBL97077)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccccc1)C(N)=O |c:23| Show InChI InChI=1S/C23H26N4O11/c1-35-16-15(31)21(27-8-7-13(29)26-23(27)34)37-17(16)18(19(24)32)38-22-14(30)11(28)9-12(36-22)20(33)25-10-5-3-2-4-6-10/h2-9,11,14-18,21-22,28,30-31H,1H3,(H2,24,32)(H,25,33)(H,26,29,34)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory concentration required against Translocase I |
Bioorg Med Chem Lett 13: 2833-6 (2003)
BindingDB Entry DOI: 10.7270/Q2VX0JP8 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221211
(CHEMBL97077)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccccc1)C(N)=O |c:23| Show InChI InChI=1S/C23H26N4O11/c1-35-16-15(31)21(27-8-7-13(29)26-23(27)34)37-17(16)18(19(24)32)38-22-14(30)11(28)9-12(36-22)20(33)25-10-5-3-2-4-6-10/h2-9,11,14-18,21-22,28,30-31H,1H3,(H2,24,32)(H,25,33)(H,26,29,34)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221473
(CHEMBL94424)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1cccc(C)c1)C(N)=O |c:23| Show InChI InChI=1S/C24H28N4O11/c1-10-4-3-5-11(8-10)26-21(34)13-9-12(29)15(31)23(37-13)39-19(20(25)33)18-17(36-2)16(32)22(38-18)28-7-6-14(30)27-24(28)35/h3-9,12,15-19,22-23,29,31-32H,1-2H3,(H2,25,33)(H,26,34)(H,27,30,35)/t12-,15-,16+,17-,18-,19+,22+,23+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025291
(2-(3,4-Dihydroxy-phenyl)-6-hexyloxy-5,7-dimethoxy-...)Show SMILES CCCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C23H26O7/c1-4-5-6-7-10-29-22-20(27-2)13-19-21(23(22)28-3)17(26)12-18(30-19)14-8-9-15(24)16(25)11-14/h8-9,11-13,24-25H,4-7,10H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025286
(2-(3,4-Dihydroxy-phenyl)-5-hexyloxy-6,7-dimethoxy-...)Show SMILES CCCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C23H26O7/c1-4-5-6-7-10-29-23-21-17(26)12-18(14-8-9-15(24)16(25)11-14)30-19(21)13-20(27-2)22(23)28-3/h8-9,11-13,24-25H,4-7,10H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025278
(6-Butoxy-2-(3,4-dihydroxy-phenyl)-5-hydroxy-7-meth...)Show SMILES CCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C20H20O7/c1-3-4-7-26-20-17(25-2)10-16-18(19(20)24)14(23)9-15(27-16)11-5-6-12(21)13(22)8-11/h5-6,8-10,21-22,24H,3-4,7H2,1-2H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221201
(CHEMBL97712)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccc(F)c(F)c1)C(N)=O |c:23| Show InChI InChI=1S/C23H24F2N4O11/c1-37-16-15(33)21(29-5-4-13(31)28-23(29)36)39-17(16)18(19(26)34)40-22-14(32)11(30)7-12(38-22)20(35)27-8-2-3-9(24)10(25)6-8/h2-7,11,14-18,21-22,30,32-33H,1H3,(H2,26,34)(H,27,35)(H,28,31,36)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025328
(2-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-5-(3-methyl...)Show SMILES COc1cc2oc(cc(=O)c2c(OCCC(C)C)c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H24O7/c1-12(2)7-8-28-22-20-16(25)10-17(13-5-6-14(23)15(24)9-13)29-18(20)11-19(26-3)21(22)27-4/h5-6,9-12,23-24H,7-8H2,1-4H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50135598
((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)Show SMILES CO[C@H]1[C@@H](O)[C@@H](O[C@@H]1[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCC[C@@H](C)NC1=O)C(N)=O)n1ccc(=O)[nH]c1=O |c:13| Show InChI InChI=1S/C24H33N5O12/c1-9-4-3-5-10(20(35)26-9)27-21(36)12-8-11(30)14(32)23(39-12)41-18(19(25)34)17-16(38-2)15(33)22(40-17)29-7-6-13(31)28-24(29)37/h6-11,14-18,22-23,30,32-33H,3-5H2,1-2H3,(H2,25,34)(H,26,35)(H,27,36)(H,28,31,37)/t9-,10+,11+,14+,15-,16+,17+,18-,22-,23-/m1/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50135598
((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)Show SMILES CO[C@H]1[C@@H](O)[C@@H](O[C@@H]1[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCC[C@@H](C)NC1=O)C(N)=O)n1ccc(=O)[nH]c1=O |c:13| Show InChI InChI=1S/C24H33N5O12/c1-9-4-3-5-10(20(35)26-9)27-21(36)12-8-11(30)14(32)23(39-12)41-18(19(25)34)17-16(38-2)15(33)22(40-17)29-7-6-13(31)28-24(29)37/h6-11,14-18,22-23,30,32-33H,3-5H2,1-2H3,(H2,25,34)(H,26,35)(H,27,36)(H,28,31,37)/t9-,10+,11+,14+,15-,16+,17+,18-,22-,23-/m1/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025307
(6-Decyloxy-2-(3,4-dihydroxy-phenyl)-5,7-dimethoxy-...)Show SMILES CCCCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C27H34O7/c1-4-5-6-7-8-9-10-11-14-33-26-24(31-2)17-23-25(27(26)32-3)21(30)16-22(34-23)18-12-13-19(28)20(29)15-18/h12-13,15-17,28-29H,4-11,14H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50135598
((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)Show SMILES CO[C@H]1[C@@H](O)[C@@H](O[C@@H]1[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCC[C@@H](C)NC1=O)C(N)=O)n1ccc(=O)[nH]c1=O |c:13| Show InChI InChI=1S/C24H33N5O12/c1-9-4-3-5-10(20(35)26-9)27-21(36)12-8-11(30)14(32)23(39-12)41-18(19(25)34)17-16(38-2)15(33)22(40-17)29-7-6-13(31)28-24(29)37/h6-11,14-18,22-23,30,32-33H,3-5H2,1-2H3,(H2,25,34)(H,26,35)(H,27,36)(H,28,31,37)/t9-,10+,11+,14+,15-,16+,17+,18-,22-,23-/m1/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory concentration against translocase-I |
Bioorg Med Chem Lett 13: 2833-6 (2003)
BindingDB Entry DOI: 10.7270/Q2VX0JP8 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50135599
((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)Show SMILES CO[C@H]1[C@@H](O)[C@@H](O[C@@H]1[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCCCNC1=O)C(N)=O)n1ccc(=O)[nH]c1=O |c:13| Show InChI InChI=1S/C23H31N5O12/c1-37-15-14(32)21(28-7-5-12(30)27-23(28)36)39-16(15)17(18(24)33)40-22-13(31)10(29)8-11(38-22)20(35)26-9-4-2-3-6-25-19(9)34/h5,7-10,13-17,21-22,29,31-32H,2-4,6H2,1H3,(H2,24,33)(H,25,34)(H,26,35)(H,27,30,36)/t9-,10-,13-,14+,15-,16-,17+,21+,22+/m0/s1 | PDB
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Curated by ChEMBL
| Assay Description
Inhibitory concentration against translocase-I |
Bioorg Med Chem Lett 13: 2833-6 (2003)
BindingDB Entry DOI: 10.7270/Q2VX0JP8 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50135599
((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)Show SMILES CO[C@H]1[C@@H](O)[C@@H](O[C@@H]1[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCCCNC1=O)C(N)=O)n1ccc(=O)[nH]c1=O |c:13| Show InChI InChI=1S/C23H31N5O12/c1-37-15-14(32)21(28-7-5-12(30)27-23(28)36)39-16(15)17(18(24)33)40-22-13(31)10(29)8-11(38-22)20(35)26-9-4-2-3-6-25-19(9)34/h5,7-10,13-17,21-22,29,31-32H,2-4,6H2,1H3,(H2,24,33)(H,25,34)(H,26,35)(H,27,30,36)/t9-,10-,13-,14+,15-,16-,17+,21+,22+/m0/s1 | PDB
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Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50135599
((4S,5S,6S)-6-{(R)-Carbamoyl-[(2S,3S,4R,5R)-5-(2,4-...)Show SMILES CO[C@H]1[C@@H](O)[C@@H](O[C@@H]1[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCCCNC1=O)C(N)=O)n1ccc(=O)[nH]c1=O |c:13| Show InChI InChI=1S/C23H31N5O12/c1-37-15-14(32)21(28-7-5-12(30)27-23(28)36)39-16(15)17(18(24)33)40-22-13(31)10(29)8-11(38-22)20(35)26-9-4-2-3-6-25-19(9)34/h5,7-10,13-17,21-22,29,31-32H,2-4,6H2,1H3,(H2,24,33)(H,25,34)(H,26,35)(H,27,30,36)/t9-,10-,13-,14+,15-,16-,17+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025309
(5-Decyloxy-2-(3,4-dihydroxy-phenyl)-6,7-dimethoxy-...)Show SMILES CCCCCCCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C27H34O7/c1-4-5-6-7-8-9-10-11-14-33-27-25-21(30)16-22(18-12-13-19(28)20(29)15-18)34-23(25)17-24(31-2)26(27)32-3/h12-13,15-17,28-29H,4-11,14H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025314
(2-(3,4-Dihydroxy-phenyl)-5-dodecyloxy-6,7-dimethox...)Show SMILES CCCCCCCCCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C29H38O7/c1-4-5-6-7-8-9-10-11-12-13-16-35-29-27-23(32)18-24(20-14-15-21(30)22(31)17-20)36-25(27)19-26(33-2)28(29)34-3/h14-15,17-19,30-31H,4-13,16H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221409
(CHEMBL96162)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1cccc(F)c1)C(N)=O |c:23| Show InChI InChI=1S/C23H25FN4O11/c1-36-16-15(32)21(28-6-5-13(30)27-23(28)35)38-17(16)18(19(25)33)39-22-14(31)11(29)8-12(37-22)20(34)26-10-4-2-3-9(24)7-10/h2-8,11,14-18,21-22,29,31-32H,1H3,(H2,25,33)(H,26,34)(H,27,30,35)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025288
(2-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-5-octyloxy-...)Show SMILES CCCCCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C25H30O7/c1-4-5-6-7-8-9-12-31-25-23-19(28)14-20(16-10-11-17(26)18(27)13-16)32-21(23)15-22(29-2)24(25)30-3/h10-11,13-15,26-27H,4-9,12H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025282
(2-(3,4-Dihydroxy-phenyl)-6-hexyloxy-5-hydroxy-7-me...)Show SMILES CCCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H24O7/c1-3-4-5-6-9-28-22-19(27-2)12-18-20(21(22)26)16(25)11-17(29-18)13-7-8-14(23)15(24)10-13/h7-8,10-12,23-24,26H,3-6,9H2,1-2H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025293
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7-methoxy-6-pen...)Show SMILES CCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C21H22O7/c1-3-4-5-8-27-21-18(26-2)11-17-19(20(21)25)15(24)10-16(28-17)12-6-7-13(22)14(23)9-12/h6-7,9-11,22-23,25H,3-5,8H2,1-2H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025290
(2-(3,4-Dihydroxy-phenyl)-5-dodecyloxy-7,8-dimethox...)Show SMILES CCCCCCCCCCCCOc1cc(OC)c(OC)c2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C29H38O7/c1-4-5-6-7-8-9-10-11-12-13-16-35-25-19-26(33-2)28(34-3)29-27(25)23(32)18-24(36-29)20-14-15-21(30)22(31)17-20/h14-15,17-19,30-31H,4-13,16H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025303
(2-(3,4-Dihydroxy-phenyl)-5,7-dimethoxy-6-octyloxy-...)Show SMILES CCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C25H30O7/c1-4-5-6-7-8-9-12-31-24-22(29-2)15-21-23(25(24)30-3)19(28)14-20(32-21)16-10-11-17(26)18(27)13-16/h10-11,13-15,26-27H,4-9,12H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221204
(CHEMBL327358)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1cccc(F)c1F)C(N)=O |c:23| Show InChI InChI=1S/C23H24F2N4O11/c1-37-16-15(33)21(29-6-5-12(31)28-23(29)36)39-17(16)18(19(26)34)40-22-14(32)10(30)7-11(38-22)20(35)27-9-4-2-3-8(24)13(9)25/h2-7,10,14-18,21-22,30,32-33H,1H3,(H2,26,34)(H,27,35)(H,28,31,36)/t10-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221205
(CHEMBL317088)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)NCCc1cccs1)C(N)=O |c:23| Show InChI InChI=1S/C23H28N4O11S/c1-35-16-15(31)21(27-7-5-13(29)26-23(27)34)37-17(16)18(19(24)32)38-22-14(30)11(28)9-12(36-22)20(33)25-6-4-10-3-2-8-39-10/h2-3,5,7-9,11,14-18,21-22,28,30-31H,4,6H2,1H3,(H2,24,32)(H,25,33)(H,26,29,34)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221054
(CHEMBL97606)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccc(C)cc1)C(N)=O |c:23| Show InChI InChI=1S/C24H28N4O11/c1-10-3-5-11(6-4-10)26-21(34)13-9-12(29)15(31)23(37-13)39-19(20(25)33)18-17(36-2)16(32)22(38-18)28-8-7-14(30)27-24(28)35/h3-9,12,15-19,22-23,29,31-32H,1-2H3,(H2,25,33)(H,26,34)(H,27,30,35)/t12-,15-,16+,17-,18-,19+,22+,23+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221475
(CHEMBL94839)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1nc(cs1)C(C)(C)C)C(N)=O |c:23| Show InChI InChI=1S/C24H31N5O11S/c1-24(2,3)11-8-41-22(26-11)28-19(35)10-7-9(30)13(32)21(38-10)40-17(18(25)34)16-15(37-4)14(33)20(39-16)29-6-5-12(31)27-23(29)36/h5-9,13-17,20-21,30,32-33H,1-4H3,(H2,25,34)(H,26,28,35)(H,27,31,36)/t9-,13-,14+,15-,16-,17+,20+,21+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025304
(2-(3,4-Dihydroxy-phenyl)-6-dodecyloxy-5-hydroxy-7-...)Show SMILES CCCCCCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1O)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C28H36O7/c1-3-4-5-6-7-8-9-10-11-12-15-34-28-25(33-2)18-24-26(27(28)32)22(31)17-23(35-24)19-13-14-20(29)21(30)16-19/h13-14,16-18,29-30,32H,3-12,15H2,1-2H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025280
(2-(3,4-Dihydroxy-phenyl)-5,7-dimethoxy-6-(3-methyl...)Show SMILES COc1cc2oc(cc(=O)c2c(OC)c1OCCC(C)C)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H24O7/c1-12(2)7-8-28-21-19(26-3)11-18-20(22(21)27-4)16(25)10-17(29-18)13-5-6-14(23)15(24)9-13/h5-6,9-12,23-24H,7-8H2,1-4H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221469
(CHEMBL329448)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccc(F)cc1F)C(N)=O |c:23| Show InChI InChI=1S/C23H24F2N4O11/c1-37-16-15(33)21(29-5-4-13(31)28-23(29)36)39-17(16)18(19(26)34)40-22-14(32)11(30)7-12(38-22)20(35)27-10-3-2-8(24)6-9(10)25/h2-7,11,14-18,21-22,30,32-33H,1H3,(H2,26,34)(H,27,35)(H,28,31,36)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025296
(2-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-5-tetradecy...)Show SMILES CCCCCCCCCCCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C31H42O7/c1-4-5-6-7-8-9-10-11-12-13-14-15-18-37-31-29-25(34)20-26(22-16-17-23(32)24(33)19-22)38-27(29)21-28(35-2)30(31)36-3/h16-17,19-21,32-33H,4-15,18H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025323
(Acetic acid 2-acetoxy-5-(5,7-dimethoxy-4-oxo-6-pen...)Show SMILES CCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(OC(C)=O)c(OC(C)=O)c1 Show InChI InChI=1S/C26H28O9/c1-6-7-8-11-32-25-23(30-4)14-22-24(26(25)31-5)18(29)13-20(35-22)17-9-10-19(33-15(2)27)21(12-17)34-16(3)28/h9-10,12-14H,6-8,11H2,1-5H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025327
(2-(3,4-Dihydroxy-phenyl)-6-dodecyloxy-5,7-dimethox...)Show SMILES CCCCCCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C29H38O7/c1-4-5-6-7-8-9-10-11-12-13-16-35-28-26(33-2)19-25-27(29(28)34-3)23(32)18-24(36-25)20-14-15-21(30)22(31)17-20/h14-15,17-19,30-31H,4-13,16H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025313
(Acetic acid 2-acetoxy-5-(6-decyloxy-5,7-dimethoxy-...)Show SMILES CCCCCCCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(OC(C)=O)c(OC(C)=O)c1 Show InChI InChI=1S/C31H38O9/c1-6-7-8-9-10-11-12-13-16-37-30-28(35-4)19-27-29(31(30)36-5)23(34)18-25(40-27)22-14-15-24(38-20(2)32)26(17-22)39-21(3)33/h14-15,17-19H,6-13,16H2,1-5H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221051
(CHEMBL319731)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)NCCc1ccc(Cl)cc1Cl)C(N)=O |c:23| Show InChI InChI=1S/C25H28Cl2N4O11/c1-39-18-17(35)23(31-7-5-15(33)30-25(31)38)41-19(18)20(21(28)36)42-24-16(34)13(32)9-14(40-24)22(37)29-6-4-10-2-3-11(26)8-12(10)27/h2-3,5,7-9,13,16-20,23-24,32,34-35H,4,6H2,1H3,(H2,28,36)(H,29,37)(H,30,33,38)/t13-,16-,17+,18-,19-,20+,23+,24+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221457
(CHEMBL94400)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccc(Cl)cc1)C(N)=O |c:23| Show InChI InChI=1S/C23H25ClN4O11/c1-36-16-15(32)21(28-7-6-13(30)27-23(28)35)38-17(16)18(19(25)33)39-22-14(31)11(29)8-12(37-22)20(34)26-10-4-2-9(24)3-5-10/h2-8,11,14-18,21-22,29,31-32H,1H3,(H2,25,33)(H,26,34)(H,27,30,35)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025324
(2-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-5-pentyloxy...)Show SMILES CCCCCOc1c(OC)c(OC)cc2oc(cc(=O)c12)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H24O7/c1-4-5-6-9-28-22-20-16(25)11-17(13-7-8-14(23)15(24)10-13)29-18(20)12-19(26-2)21(22)27-3/h7-8,10-12,23-24H,4-6,9H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221331
(CHEMBL430672)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)NCCc1cccc(OC)c1)C(N)=O |c:23| Show InChI InChI=1S/C26H32N4O12/c1-38-13-5-3-4-12(10-13)6-8-28-23(36)15-11-14(31)17(33)25(40-15)42-21(22(27)35)20-19(39-2)18(34)24(41-20)30-9-7-16(32)29-26(30)37/h3-5,7,9-11,14,17-21,24-25,31,33-34H,6,8H2,1-2H3,(H2,27,35)(H,28,36)(H,29,32,37)/t14-,17-,18+,19-,20-,21+,24+,25+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221407
(CHEMBL418960)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccc(Br)cc1)C(N)=O |c:23| Show InChI InChI=1S/C23H25BrN4O11/c1-36-16-15(32)21(28-7-6-13(30)27-23(28)35)38-17(16)18(19(25)33)39-22-14(31)11(29)8-12(37-22)20(34)26-10-4-2-9(24)3-5-10/h2-8,11,14-18,21-22,29,31-32H,1H3,(H2,25,33)(H,26,34)(H,27,30,35)/t11-,14-,15+,16-,17-,18+,21+,22+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025310
(2-(3,4-Dihydroxy-phenyl)-7-dodecyloxy-5,8-dimethox...)Show SMILES CCCCCCCCCCCCOc1cc(OC)c2c(oc(cc2=O)-c2ccc(O)c(O)c2)c1OC Show InChI InChI=1S/C29H38O7/c1-4-5-6-7-8-9-10-11-12-13-16-35-26-19-25(33-2)27-23(32)18-24(36-29(27)28(26)34-3)20-14-15-21(30)22(31)17-20/h14-15,17-19,30-31H,4-13,16H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221408
(CHEMBL97276)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1nccs1)C(N)=O |c:23| Show InChI InChI=1S/C20H23N5O11S/c1-33-12-11(29)17(25-4-2-9(27)23-20(25)32)35-13(12)14(15(21)30)36-18-10(28)7(26)6-8(34-18)16(31)24-19-22-3-5-37-19/h2-7,10-14,17-18,26,28-29H,1H3,(H2,21,30)(H,22,24,31)(H,23,27,32)/t7-,10-,11+,12-,13-,14+,17+,18+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221330
(CHEMBL96561)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)NCCc1cccc(Cl)c1)C(N)=O |c:23| Show InChI InChI=1S/C25H29ClN4O11/c1-38-18-17(34)23(30-8-6-15(32)29-25(30)37)40-19(18)20(21(27)35)41-24-16(33)13(31)10-14(39-24)22(36)28-7-5-11-3-2-4-12(26)9-11/h2-4,6,8-10,13,16-20,23-24,31,33-34H,5,7H2,1H3,(H2,27,35)(H,28,36)(H,29,32,37)/t13-,16-,17+,18-,19-,20+,23+,24+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221060
(CHEMBL95074)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)NCCc1ccc(Cl)cc1)C(N)=O |c:23| Show InChI InChI=1S/C25H29ClN4O11/c1-38-18-17(34)23(30-9-7-15(32)29-25(30)37)40-19(18)20(21(27)35)41-24-16(33)13(31)10-14(39-24)22(36)28-8-6-11-2-4-12(26)5-3-11/h2-5,7,9-10,13,16-20,23-24,31,33-34H,6,8H2,1H3,(H2,27,35)(H,28,36)(H,29,32,37)/t13-,16-,17+,18-,19-,20+,23+,24+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50025297
(2-(3,4-Dihydroxy-phenyl)-5,7-dimethoxy-6-pentyloxy...)Show SMILES CCCCCOc1c(OC)cc2oc(cc(=O)c2c1OC)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H24O7/c1-4-5-6-9-28-21-19(26-2)12-18-20(22(21)27-3)16(25)11-17(29-18)13-7-8-14(23)15(24)10-13/h7-8,10-12,23-24H,4-6,9H2,1-3H3 | PDB
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TBA
Curated by ChEMBL
| Assay Description
Ability to inhibit 5-lipoxygenase in rat basophilic leukemia cells. |
J Med Chem 29: 2256-62 (1986)
BindingDB Entry DOI: 10.7270/Q2M907P5 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221055
(CHEMBL316294)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccc(CC)cc1)C(N)=O |c:23| Show InChI InChI=1S/C25H30N4O11/c1-3-11-4-6-12(7-5-11)27-22(35)14-10-13(30)16(32)24(38-14)40-20(21(26)34)19-18(37-2)17(33)23(39-19)29-9-8-15(31)28-25(29)36/h4-10,13,16-20,23-24,30,32-33H,3H2,1-2H3,(H2,26,34)(H,27,35)(H,28,31,36)/t13-,16-,17+,18-,19-,20+,23+,24+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221212
(CHEMBL318123)Show SMILES [H][C@@]1(O[C@H]([C@H](O)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)Nc1ccccc1OCc1ccccc1)C(N)=O |c:23| Show InChI InChI=1S/C30H32N4O12/c1-42-23-22(38)28(34-12-11-20(36)33-30(34)41)45-24(23)25(26(31)39)46-29-21(37)17(35)13-19(44-29)27(40)32-16-9-5-6-10-18(16)43-14-15-7-3-2-4-8-15/h2-13,17,21-25,28-29,35,37-38H,14H2,1H3,(H2,31,39)(H,32,40)(H,33,36,41)/t17-,21-,22+,23-,24-,25+,28+,29+/m0/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory activity against translocase I |
Bioorg Med Chem Lett 13: 2829-32 (2003)
BindingDB Entry DOI: 10.7270/Q2TD9WR7 |
More data for this
Ligand-Target Pair | |
Phospho-N-acetylmuramoyl-pentapeptide-transferase
(Escherichia coli (strain K12)) | BDBM50221487
(CHEMBL94502)Show SMILES [H][C@@]1(O[C@H]([C@H](OC(=O)CCCC)[C@@H]1OC)n1ccc(=O)[nH]c1=O)[C@@H](O[C@H]1OC(=C[C@H](O)[C@@H]1O)C(=O)N[C@H]1CCC[C@@H](C)NC1=O)C(N)=O |c:29| Show InChI InChI=1S/C29H41N5O13/c1-4-5-9-18(37)45-23-20(43-3)21(46-27(23)34-11-10-17(36)33-29(34)42)22(24(30)39)47-28-19(38)15(35)12-16(44-28)26(41)32-14-8-6-7-13(2)31-25(14)40/h10-15,19-23,27-28,35,38H,4-9H2,1-3H3,(H2,30,39)(H,31,40)(H,32,41)(H,33,36,42)/t13-,14+,15+,19+,20-,21+,22-,23-,27-,28-/m1/s1 | PDB
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Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibitory concentration required against Translocase I |
Bioorg Med Chem Lett 13: 2833-6 (2003)
BindingDB Entry DOI: 10.7270/Q2VX0JP8 |
More data for this
Ligand-Target Pair | |
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