| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1F |
|---|
| Ligand | BDBM50130443 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_2086 |
|---|
| Ki | 7.6±n/a nM |
|---|
| Citation |  Mathes, BM; Hudziak, KJ; Schaus, JM; Xu, YC; Nelson, DL; Wainscott, DB; Nutter, SE; Gough, WH; Branchek, TA; Zgombick, JM; Filla, SA Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. Bioorg Med Chem Lett14:167-70 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1F |
|---|
| Name: | 5-hydroxytryptamine receptor 1F |
|---|
| Synonyms: | 5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5HT1F_HUMAN | HTR1EL | HTR1F | Serotonin (5-HT) receptor | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41724.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | 5-HT1F HTR1F HUMAN::P30939 |
|---|
| Residue: | 366 |
|---|
| Sequence: | MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
|
|
|
|---|
| BDBM50130443 |
|---|
| n/a |
|---|
| Name | BDBM50130443 |
|---|
| Synonyms: | 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-benzamide | CHEMBL103479 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21FN4O |
|---|
| Mol. Mass. | 352.4053 |
|---|
| SMILES | CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12 |
|---|
| Structure | 
|
|---|
Search and Browse
