| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1F |
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| Ligand | BDBM50137542 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_2086 |
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| Ki | 8.2±n/a nM |
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| Citation |  Mathes, BM; Hudziak, KJ; Schaus, JM; Xu, YC; Nelson, DL; Wainscott, DB; Nutter, SE; Gough, WH; Branchek, TA; Zgombick, JM; Filla, SA Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. Bioorg Med Chem Lett14:167-70 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1F |
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| Name: | 5-hydroxytryptamine receptor 1F |
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| Synonyms: | 5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5HT1F_HUMAN | HTR1EL | HTR1F | Serotonin (5-HT) receptor | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41724.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | 5-HT1F HTR1F HUMAN::P30939 |
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| Residue: | 366 |
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| Sequence: | MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
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|
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| BDBM50137542 |
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| n/a |
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| Name | BDBM50137542 |
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| Synonyms: | CHEMBL178066 | N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-5-yl]-4-fluoro-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22FN3O |
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| Mol. Mass. | 339.4066 |
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| SMILES | CN(C)CCc1c(C)[nH]c2ccc(NC(=O)c3ccc(F)cc3)cc12 |
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| Structure | 
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