| Reaction Details |
|---|
 | Report a problem with these data |
| Target | G2/mitotic-specific cyclin-B1 |
|---|
| Ligand | BDBM50140085 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_144034 (CHEMBL872836) |
|---|
| IC50 | 252±n/a nM |
|---|
| Citation |  Loughnan, ML; Nicke, A; Jones, A; Adams, DJ; Alewood, PF; Lewis, RJ Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. J Med Chem47:1234-41 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| G2/mitotic-specific cyclin-B1 |
|---|
| Name: | G2/mitotic-specific cyclin-B1 |
|---|
| Synonyms: | CCNB1_RAT | Ccnb1 | G2/mitotic-specific cyclin B1 | G2/mitotic-specific cyclin-B1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47397.83 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_144034 |
|---|
| Residue: | 423 |
|---|
| Sequence: | MALRVTRNTKINTENKAKVSMAGAKRVPVAVAASKPLLRSRTALGDIGNKVSEQSRIPLK
KETKKLGSGTVTVKALPKPVDKVPVCEPEVELDEPEPEPVMEVKHSPEPILVDTPSPSPM
ETSGCAPAEEYLCQAFSDVILAVSDVDADDGGDPNLCSEYVKDIYAYLRQLEEEQSVRPK
YLLGREVTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQDSCVPKKMLQLVGVT
AMFIASKYEEMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFSLGRPLPLHFLRRAS
KIGEVDVEQHTLAKYLMELSMLDYDMVHFAPSQIAAGAFCLALKILDNGEWTPTLQHYLS
HTEESLLPVMQHLAKNIVMVNRGLTKHMTIKNKYATSKHAKISTLAQLNCTLVQNLSKAV
TKA
|
|
|
|---|
| BDBM50140085 |
|---|
| n/a |
|---|
| Name | BDBM50140085 |
|---|
| Synonyms: | CHEMBL266702 | GCCSLPPCAANNPDYC* |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C65H99N19O21S5 |
|---|
| Mol. Mass. | 1642.921 |
|---|
| SMILES | CC(C)C[C@@H](NC(=O)[C@@H](CO)NC(=O)[C@@H](CS)NC(=O)[C@@H](CS)NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(S)cc1)C(=O)N[C@@H](CS)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
