| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50106820 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_39051 |
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| Ki | 81±n/a nM |
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| Citation |  Washburn, WN; Sun, CQ; Bisacchi, G; Wu, G; Cheng, PT; Sher, PM; Ryono, D; Gavai, AV; Poss, K; Girotra, RN; McCann, PJ; Mikkilineni, AB; Dejneka, TC; Wang, TC; Merchant, Z; Morella, M; Arbeeny, CM; Harper, TW; Slusarchyk, DA; Skwish, S; Russell, AD; Allen, GT; Tesfamariam, B; Frohlich, BH; Abboa-Offei, BE; Cap, M; Waldron, TL; George, RJ; Young, D; Dickinson, KE; Seymour, AA BMS-201620: a selective beta 3 agonist. Bioorg Med Chem Lett14:3525-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50106820 |
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| n/a |
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| Name | BDBM50106820 |
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| Synonyms: | (R)-N-(5-(2-(bis(4-methoxyphenyl)methylamino)-1-hydroxyethyl)-2-hydroxyphenyl)methanesulfonamide | CHEMBL102836 | N-[(R)-5-(2-{[Bis-(4-methoxy-phenyl)-methyl]-amino}-1-hydroxy-ethyl)-2-hydroxy-phenyl]-methanesulfonamide | N-[5-((R)-2-{[Bis-(4-methoxy-phenyl)-methyl]-amino}-1-hydroxy-ethyl)-2-hydroxy-phenyl]-methanesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28N2O6S |
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| Mol. Mass. | 472.554 |
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| SMILES | COc1ccc(cc1)C(NC[C@H](O)c1ccc(O)c(NS(C)(=O)=O)c1)c1ccc(OC)cc1 |
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| Structure | 
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