| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50150033 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302271 (CHEMBL830291) |
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| Ki | 1.37±n/a nM |
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| Citation |  Huang, PP; Randolph, JT; Klein, LL; Vasavanonda, S; Dekhtyar, T; Stoll, VS; Kempf, DJ Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors. Bioorg Med Chem Lett14:4075-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50150033 |
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| n/a |
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| Name | BDBM50150033 |
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| Synonyms: | (5R,6R)-1-Benzenesulfonyl-5-benzyl-6-hydroxy-2,4-bis-(4-hydroxy-benzyl)-[1,2,4]triazepan-3-one | CHEMBL183451 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H31N3O6S |
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| Mol. Mass. | 573.659 |
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| SMILES | O[C@@H]1CN(N(Cc2ccc(O)cc2)C(=O)N(Cc2ccc(O)cc2)[C@@H]1Cc1ccccc1)S(=O)(=O)c1ccccc1 |
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| Structure | 
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