| Reaction Details |
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 | Report a problem with these data |
| Target | Galectin-1 |
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| Ligand | BDBM50581778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2152219 (CHEMBL5036766) |
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| IC50 | 296±n/a nM |
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| Citation |  Xu, L; Hartz, RA; Beno, BR; Ghosh, K; Shukla, JK; Kumar, A; Patel, D; Kalidindi, N; Lemos, N; Gautam, SS; Kumar, A; Ellsworth, BA; Shah, D; Sale, H; Cheng, D; Regueiro-Ren, A Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors. J Med Chem64:6634-6655 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galectin-1 |
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| Name: | Galectin-1 |
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| Synonyms: | 14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12 |
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| Type: | beta galactoside-binding protein |
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| Mol. Mass.: | 14713.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09382 |
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| Residue: | 135 |
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| Sequence: | MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIV
CNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINY
MAADGDFKIKCVAFD
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| BDBM50581778 |
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| n/a |
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| Name | BDBM50581778 |
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| Synonyms: | CHEMBL5090468 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H29F3N8O7S |
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| Mol. Mass. | 666.629 |
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| SMILES | [H][C@]1(COC[C@@H]([C@H]1O)n1cc(nn1)-c1cnc(OC)nc1)S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1OC)n1cc(nn1)-c1cc(F)c(F)c(F)c1 |r| |
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| Structure | 
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