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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Small conductance calcium-activated potassium channel protein 2 | ||
| Ligand | BDBM50583198 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2156785 (CHEMBL5041445) | ||
| EC50 | >100000±n/a nM | ||
| Citation |  El-Sayed, NS; Nam, YW; Egorova, PA; Nguyen, HM; Orfali, R; Rahman, MA; Yang, G; Wulff, H; Bezprozvanny, I; Parang, K; Zhang, M Structure-Activity Relationship Study of Subtype-Selective Positive Modulators of K J Med Chem65:303-322 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Small conductance calcium-activated potassium channel protein 2 | |||
| Name: | Small conductance calcium-activated potassium channel protein 2 | ||
| Synonyms: | KCNN2_RAT | Kcnn2 | Small conductance calcium-activated potassium channel | Small conductance calcium-activated potassium channel protein 2 | Small conductance calcium-activated potassium channel protein 2 (KCa2.2) | ||
| Type: | Protein | ||
| Mol. Mass.: | 63876.72 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | P70604 | ||
| Residue: | 580 | ||
| Sequence: |
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| BDBM50583198 | |||
| n/a | |||
| Name | BDBM50583198 | ||
| Synonyms: | CHEMBL5090455 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H25N5O | ||
| Mol. Mass. | 315.4133 | ||
| SMILES | Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H]2CC[C@H](CO)CC2)n1 |r,wD:14.14,17.18,(49.78,-10.62,;48.25,-10.79,;47.48,-12.12,;45.97,-11.8,;44.83,-12.83,;45.81,-10.27,;47.21,-9.64,;44.47,-9.51,;43.13,-10.28,;41.8,-9.51,;40.47,-10.28,;41.8,-7.96,;43.13,-7.19,;43.13,-5.65,;44.46,-4.88,;44.45,-3.34,;45.78,-2.57,;47.12,-3.33,;48.45,-2.56,;49.79,-3.32,;47.13,-4.87,;45.79,-5.65,;44.47,-7.96,)| | ||
| Structure | 
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