| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA polymerase beta |
|---|
| Ligand | BDBM50153117 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_306178 (CHEMBL830972) |
|---|
| IC50 | 11000±n/a nM |
|---|
| Citation |  Oshige, M; Kuramochi, K; Ohta, K; Ogawa, A; Kuriyama, H; Sugawara, F; Kobayashi, S; Sakaguchi, K Molecular design of cholesterols as inhibitors of DNA polymerase alpha. J Med Chem47:4971-4 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA polymerase beta |
|---|
| Name: | DNA polymerase beta |
|---|
| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38334.34 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1361926 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
|
|
|
|---|
| BDBM50153117 |
|---|
| n/a |
|---|
| Name | BDBM50153117 |
|---|
| Synonyms: | (S)-4-((5R,10R,13R,17R)-3-Hydroxy-5,10,13-trimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid | CHEMBL362353 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H42O3 |
|---|
| Mol. Mass. | 390.5992 |
|---|
| SMILES | C[C@@H](CCC(O)=O)[C@H]1CCC2C3CC[C@]4(C)CC(O)CC[C@]4(C)C3CC[C@]12C |
|---|
| Structure | 
|
|---|
Search and Browse
