| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50585113 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2161630 (CHEMBL5046491) |
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| Ki | 38±n/a nM |
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| Citation |  Bonifazi, A; Battiti, FO; Sanchez, J; Zaidi, SA; Bow, E; Makarova, M; Cao, J; Shaik, AB; Sulima, A; Rice, KC; Katritch, V; Canals, M; Lane, JR; Newman, AH Novel Dual-Target ?-Opioid Receptor and Dopamine D J Med Chem64:7778-7808 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50585113 |
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| n/a |
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| Name | BDBM50585113 |
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| Synonyms: | CHEMBL5074399 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H45ClN4O |
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| Mol. Mass. | 561.2 |
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| SMILES | CCc1cccc(N2CCN(CCCCNCCC(C(=O)N(C)C)(c3ccccc3)c3ccccc3)CC2)c1Cl |
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| Structure | 
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