Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 6 |
---|
Ligand | BDBM50155131 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_303107 (CHEMBL829617) |
---|
Ki | 27±n/a nM |
---|
Citation | Bernotas, R; Lenicek, S; Antane, S; Zhang, GM; Smith, D; Coupet, J; Harrison, B; Schechter, LE 1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-indoles as novel 5-HT6 receptor ligands. Bioorg Med Chem Lett14:5499-502 (2004) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
5-hydroxytryptamine receptor 6 |
---|
Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
|
|
|
BDBM50155131 |
---|
n/a |
---|
Name | BDBM50155131 |
Synonyms: | 2-(3-Benzenesulfonyl-5-fluoro-indol-1-yl)-ethylamine | CHEMBL186585 |
Type | Small organic molecule |
Emp. Form. | C16H15FN2O2S |
Mol. Mass. | 318.366 |
SMILES | NCCn1cc(c2cc(F)ccc12)S(=O)(=O)c1ccccc1 |
Structure |
|