| Reaction Details |
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 | Report a problem with these data |
| Target | 14-3-3 protein eta |
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| Ligand | BDBM50591820 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2201840 (CHEMBL5114548) |
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| Kd | >200000±n/a nM |
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| Citation |  Gao, Z; Fan, T; Chen, L; Yang, M; Wai Wong, VK; Chen, D; Liu, Z; Zhou, Y; Wu, W; Qiu, Z; Zhang, C; Li, Y; Jiang, Y Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3? protein. Eur J Med Chem238:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 14-3-3 protein eta |
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| Name: | 14-3-3 protein eta |
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| Synonyms: | 14-3-3 protein eta | 1433F_HUMAN | Protein AS1 | YWHA1 | YWHAH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28205.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_110546 |
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| Residue: | 246 |
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| Sequence: | MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW
RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK
VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS
VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE
EAGEGN
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| BDBM50591820 |
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| n/a |
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| Name | BDBM50591820 |
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| Synonyms: | CHEMBL5187121 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25FN2O3 |
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| Mol. Mass. | 432.4867 |
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| SMILES | COc1cccc(CNCc2c(C(O)=O)n(Cc3ccccc3F)c3cc(C)ccc23)c1 |
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| Structure | 
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