| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily D member 3 |
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| Ligand | BDBM50592581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2204572 (CHEMBL5117280) |
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| IC50 | >13300±n/a nM |
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| Citation |  Luo, W; Huang, Z; Xu, D; Yang, M; Zhu, Y; Shen, L; Chen, S; Tao, X; Bin, W; Hu, Y; Franzblau, SG; Jiang, N; Wei, Y; Wei, X; Ding, CZ Discovery and preclinical evaluations of JBD0131, a novel nitrodihydro-imidazooxazole anti-tuberculosis agent. Bioorg Med Chem Lett72:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily D member 3 |
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| Name: | Potassium voltage-gated channel subfamily D member 3 |
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| Synonyms: | KCND3 | KCND3_HUMAN | Kv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3 | Potassium voltage-gated channel subfamily D member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv4.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73464.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1478652 |
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| Residue: | 655 |
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| Sequence: | MAAGVAAWLPFARAAAIGWMPVANCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLER
YPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAF
YGILPEIIGDCCYEEYKDRKRENAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTST
LALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVE
YLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVTLRVFRVFRIFKF
SRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWY
TIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRR
AQKKARLARIRVAKTGSSNAYLHSKRNGLLNEALELTGTPEEEHMGKTTSLIESQHHHLL
HCLEKTTGLSYLVDDPLLSVRTSTIKNHEFIDEQMFEQNCMESSMQNYPSTRSPSLSSHP
GLTTTCCSRRSKKTTHLPNSNLPATRLRSMQELSTIHIQGSEQPSLTTSRSSLNLKADDG
LRPNCKTSQITTAIISIPTPPALTPEGESRPPPASPGPNTNIPSIASNVVKVSAL
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| BDBM50592581 |
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| n/a |
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| Name | BDBM50592581 |
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| Synonyms: | CHEMBL5180874 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17FN4OS |
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| Mol. Mass. | 332.396 |
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| SMILES | C[C@]1(CN2Cc3nc(sc3C2)-c2ccc(F)cc2)CN=C(N)O1 |r,t:22| |
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| Structure | 
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