| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP2 subtype |
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| Ligand | BDBM50136234 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303060 (CHEMBL828886) |
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| Ki | >1000±n/a nM |
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| Citation |  Hattori, K; Tanaka, A; Fujii, N; Takasugi, H; Tenda, Y; Tomita, M; Nakazato, S; Nakano, K; Kato, Y; Kono, Y; Murai, H; Sakane, K Discovery of diphenyloxazole and Ndelta-Z-ornithine derivatives as highly potent and selective human prostaglandin EP(4) receptor antagonists. J Med Chem48:3103-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP2 subtype |
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| Name: | Prostaglandin E2 receptor EP2 subtype |
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| Synonyms: | PE2R2_HUMAN | PGE receptor EP2 subtype | PTGER2 | Prostaglandin E2 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP4 subtype | Prostanoid EP2 Receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39775.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43116 |
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| Residue: | 358 |
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| Sequence: | MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
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| BDBM50136234 |
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| n/a |
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| Name | BDBM50136234 |
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| Synonyms: | CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-phenoxy}-acetate | Sodium; {3-[(S)-2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-phenoxy}-acetate | Sodium; {3-[2-(4,5-diphenyl-oxazol-2-yl)-cyclohex-2-enylmethyl]-phenoxy}-acetate | sodium (S)-2-(3-((2-(4,5-diphenyloxazol-2-yl)cyclohex-2-enyl)methyl)phenoxy)acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C30H26NO4 |
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| Mol. Mass. | 464.5323 |
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| SMILES | [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15| |
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| Structure | 
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