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Compile Data Set for Download or QSAR

Found 209 hits with Last Name = 'takasugi' and Initial = 'h'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165949
PNG
(C-Phenyl-N-{3-[2-((S)-5-phenyl-4-phenyl-oxazol-2-y...)
Show SMILES O=C(NS(=O)(=O)Cc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:24|
Show InChI InChI=1S/C36H32N2O4S/c39-35(38-43(40,41)25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(42-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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0.300n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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0.680n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Rattus norvegicus)
BDBM50165949
PNG
(C-Phenyl-N-{3-[2-((S)-5-phenyl-4-phenyl-oxazol-2-y...)
Show SMILES O=C(NS(=O)(=O)Cc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:24|
Show InChI InChI=1S/C36H32N2O4S/c39-35(38-43(40,41)25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(42-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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0.740n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165948
PNG
(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Show SMILES OC(=O)CCCCCNC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C28H33N3O7/c32-25(33)15-5-2-8-16-29-26(34)22(31-27(35)24-18-21-12-6-7-14-23(21)38-24)13-9-17-30-28(36)37-19-20-10-3-1-4-11-20/h1,3-4,6-7,10-12,14,18,22H,2,5,8-9,13,15-17,19H2,(H,29,34)(H,30,36)(H,31,35)(H,32,33)/t22-/m0/s1
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0.910n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Rattus norvegicus)
BDBM50165948
PNG
(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-5-benzylo...)
Show SMILES OC(=O)CCCCCNC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C28H33N3O7/c32-25(33)15-5-2-8-16-29-26(34)22(31-27(35)24-18-21-12-6-7-14-23(21)38-24)13-9-17-30-28(36)37-19-20-10-3-1-4-11-20/h1,3-4,6-7,10-12,14,18,22H,2,5,8-9,13,15-17,19H2,(H,29,34)(H,30,36)(H,31,35)(H,32,33)/t22-/m0/s1
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5.10n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of rat prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165946
PNG
(3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclohex-2-eny...)
Show SMILES OC(=O)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:13|
Show InChI InChI=1S/C29H25NO3/c31-29(32)24-16-9-10-20(19-24)18-23-15-7-8-17-25(23)28-30-26(21-11-3-1-4-12-21)27(33-28)22-13-5-2-6-14-22/h1-6,9-14,16-17,19,23H,7-8,15,18H2,(H,31,32)/t23-/m0/s1
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5.5n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50168287
PNG
(CHEMBL363800 | Sodium; {3-[(1R,2S,6S)-1-(4,5-diphe...)
Show SMILES [O-]C(=O)COc1cccc(C[C@@H]2CCC[C@@H]3O[C@]23c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1
Show InChI InChI=1S/C30H27NO5/c32-26(33)19-34-24-15-7-9-20(18-24)17-23-14-8-16-25-30(23,36-25)29-31-27(21-10-3-1-4-11-21)28(35-29)22-12-5-2-6-13-22/h1-7,9-13,15,18,23,25H,8,14,16-17,19H2,(H,32,33)/p-1/t23-,25-,30+/m0/s1
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6.10n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human Prostanoid IP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165951
PNG
(6-{(S)-2-[(Benzofuran-2-carbonyl)-amino]-6-benzylo...)
Show SMILES OC(=O)CCCCCNC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C29H35N3O7/c33-26(34)16-5-2-9-17-30-27(35)23(32-28(36)25-19-22-13-6-7-15-24(22)39-25)14-8-10-18-31-29(37)38-20-21-11-3-1-4-12-21/h1,3-4,6-7,11-13,15,19,23H,2,5,8-10,14,16-18,20H2,(H,30,35)(H,31,37)(H,32,36)(H,33,34)/t23-/m0/s1
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8.40n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50168291
PNG
(CHEMBL363350 | Sodium; {3-[(S)-2-(4,5-diphenyl-oxa...)
Show SMILES [O-]C(=O)COc1cccc(C[C@@H]2CCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:14|
Show InChI InChI=1S/C29H25NO4/c31-26(32)19-33-24-15-7-9-20(18-24)17-23-14-8-16-25(23)29-30-27(21-10-3-1-4-11-21)28(34-29)22-12-5-2-6-13-22/h1-7,9-13,15-16,18,23H,8,14,17,19H2,(H,31,32)/p-1/t23-/m0/s1
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41n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human Prostanoid IP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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43n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165944
PNG
(CHEMBL189378 | {3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl...)
Show SMILES OC(=O)Cc1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:14|
Show InChI InChI=1S/C30H27NO3/c32-27(33)20-22-11-9-10-21(18-22)19-25-16-7-8-17-26(25)30-31-28(23-12-3-1-4-13-23)29(34-30)24-14-5-2-6-15-24/h1-6,9-15,17-18,25H,7-8,16,19-20H2,(H,32,33)/t25-/m0/s1
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50n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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54n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human Prostanoid IP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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54n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human prostanoid IP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165950
PNG
(CHEMBL192303 | {(S)-4-[(S)-1-(Benzyl-methyl-carbam...)
Show SMILES CN(Cc1ccccc1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C39H41N5O5/c1-44(26-29-16-7-3-8-17-29)38(47)35(24-28-14-5-2-6-15-28)43-36(45)33(42-37(46)34-25-31-20-11-12-21-32(31)41-34)22-13-23-40-39(48)49-27-30-18-9-4-10-19-30/h2-12,14-21,25,33,35,41H,13,22-24,26-27H2,1H3,(H,40,48)(H,42,46)(H,43,45)/t33-,35-/m0/s1
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80n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50165944
PNG
(CHEMBL189378 | {3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl...)
Show SMILES OC(=O)Cc1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:14|
Show InChI InChI=1S/C30H27NO3/c32-27(33)20-22-11-9-10-21(18-22)19-25-16-7-8-17-26(25)30-31-28(23-12-3-1-4-13-23)29(34-30)24-14-5-2-6-15-24/h1-6,9-15,17-18,25H,7-8,16,19-20H2,(H,32,33)/t25-/m0/s1
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170n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human prostanoid IP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50165947
PNG
(6-{(R)-2-[(Benzofuran-2-carbonyl)-amino]-6-benzylo...)
Show SMILES OC(=O)CCCCCNC(=O)[C@@H](CCCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C29H35N3O7/c33-26(34)16-5-2-9-17-30-27(35)23(32-28(36)25-19-22-13-6-7-15-24(22)39-25)14-8-10-18-31-29(37)38-20-21-11-3-1-4-12-21/h1,3-4,6-7,11-13,15,19,23H,2,5,8-10,14,16-18,20H2,(H,30,35)(H,31,37)(H,32,36)(H,33,34)/t23-/m1/s1
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240n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50165946
PNG
(3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclohex-2-eny...)
Show SMILES OC(=O)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:13|
Show InChI InChI=1S/C29H25NO3/c31-29(32)24-16-9-10-20(19-24)18-23-15-7-8-17-25(23)28-30-26(21-11-3-1-4-12-21)27(33-28)22-13-5-2-6-14-22/h1-6,9-14,16-17,19,23H,7-8,15,18H2,(H,31,32)/t23-/m0/s1
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610n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human prostanoid IP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50168287
PNG
(CHEMBL363800 | Sodium; {3-[(1R,2S,6S)-1-(4,5-diphe...)
Show SMILES [O-]C(=O)COc1cccc(C[C@@H]2CCC[C@@H]3O[C@]23c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1
Show InChI InChI=1S/C30H27NO5/c32-26(33)19-34-24-15-7-9-20(18-24)17-23-14-8-16-25-30(23,36-25)29-31-27(21-10-3-1-4-11-21)28(35-29)22-12-5-2-6-13-22/h1-7,9-13,15,18,23,25H,8,14,16-17,19H2,(H,32,33)/p-1/t23-,25-,30+/m0/s1
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930n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ-29,548 binding to human Prostanoid TP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 binding to human Prostanoid DP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGF-2 binding to human Prostanoid FP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to Prostanoid EP1 receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to Prostanoid EP2 receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibtion of [3H]-PGD-2 binding to human prostanoid DP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human prostanoid IP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP2 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ-29,548 binding to human Prostanoid TP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50165943
PNG
((S)-2-{(S)-5-Benzyloxycarbonylamino-2-[(1H-indole-...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=O)OCc1ccccc1)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C31H32N4O6/c36-28(35-27(30(38)39)18-21-10-3-1-4-11-21)25(34-29(37)26-19-23-14-7-8-15-24(23)33-26)16-9-17-32-31(40)41-20-22-12-5-2-6-13-22/h1-8,10-15,19,25,27,33H,9,16-18,20H2,(H,32,40)(H,34,37)(H,35,36)(H,38,39)/t25-,27-/m0/s1
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>1.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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1.02E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to Prostanoid EP4 receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype


(Homo sapiens (Human))
BDBM50136234
PNG
(CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...)
Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15|
Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1
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1.02E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP4 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype


(Homo sapiens (Human))
BDBM50168287
PNG
(CHEMBL363800 | Sodium; {3-[(1R,2S,6S)-1-(4,5-diphe...)
Show SMILES [O-]C(=O)COc1cccc(C[C@@H]2CCC[C@@H]3O[C@]23c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1
Show InChI InChI=1S/C30H27NO5/c32-26(33)19-34-24-15-7-9-20(18-24)17-23-14-8-16-25-30(23,36-25)29-31-27(21-10-3-1-4-11-21)28(35-29)22-12-5-2-6-13-22/h1-7,9-13,15,18,23,25H,8,14,16-17,19H2,(H,32,33)/p-1/t23-,25-,30+/m0/s1
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1.40E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to Prostanoid EP2 receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50165946
PNG
(3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclohex-2-eny...)
Show SMILES OC(=O)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:13|
Show InChI InChI=1S/C29H25NO3/c31-29(32)24-16-9-10-20(19-24)18-23-15-7-8-17-25(23)28-30-26(21-11-3-1-4-12-21)27(33-28)22-13-5-2-6-14-22/h1-6,9-14,16-17,19,23H,7-8,15,18H2,(H,31,32)/t23-/m0/s1
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2.50E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin D2 receptor


(Homo sapiens (Human))
BDBM50168287
PNG
(CHEMBL363800 | Sodium; {3-[(1R,2S,6S)-1-(4,5-diphe...)
Show SMILES [O-]C(=O)COc1cccc(C[C@@H]2CCC[C@@H]3O[C@]23c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1
Show InChI InChI=1S/C30H27NO5/c32-26(33)19-34-24-15-7-9-20(18-24)17-23-14-8-16-25-30(23,36-25)29-31-27(21-10-3-1-4-11-21)28(35-29)22-12-5-2-6-13-22/h1-7,9-13,15,18,23,25H,8,14,16-17,19H2,(H,32,33)/p-1/t23-,25-,30+/m0/s1
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2.90E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGD-2 binding to human Prostanoid DP receptor


Bioorg Med Chem Lett 15: 3284-7 (2005)


Article DOI: 10.1016/j.bmcl.2005.04.076
BindingDB Entry DOI: 10.7270/Q2C53KCV
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50165949
PNG
(C-Phenyl-N-{3-[2-((S)-5-phenyl-4-phenyl-oxazol-2-y...)
Show SMILES O=C(NS(=O)(=O)Cc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:24|
Show InChI InChI=1S/C36H32N2O4S/c39-35(38-43(40,41)25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(42-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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>3.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-SQ-29,548 binding to human prostanoid TP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostacyclin receptor


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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>3.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-Iloprost binding to human prostanoid IP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50165946
PNG
(3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclohex-2-eny...)
Show SMILES OC(=O)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:13|
Show InChI InChI=1S/C29H25NO3/c31-29(32)24-16-9-10-20(19-24)18-23-15-7-8-17-25(23)28-30-26(21-11-3-1-4-12-21)27(33-28)22-13-5-2-6-14-22/h1-6,9-14,16-17,19,23H,7-8,15,18H2,(H,31,32)/t23-/m0/s1
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>3.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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>3.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP3 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype


(Homo sapiens (Human))
BDBM50165945
PNG
(CHEMBL371394 | N-Benzyloxy-3-[(S)-2-(4,5-diphenyl-...)
Show SMILES O=C(NOCc1ccccc1)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:22|
Show InChI InChI=1S/C36H32N2O3/c39-35(38-40-25-26-13-4-1-5-14-26)31-21-12-15-27(24-31)23-30-20-10-11-22-32(30)36-37-33(28-16-6-2-7-17-28)34(41-36)29-18-8-3-9-19-29/h1-9,12-19,21-22,24,30H,10-11,20,23,25H2,(H,38,39)/t30-/m0/s1
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>3.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGE-2 binding to human prostanoid EP1 receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50165946
PNG
(3-[(S)-2-(4,5-Diphenyl-oxazol-2-yl)-cyclohex-2-eny...)
Show SMILES OC(=O)c1cccc(C[C@@H]2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:13|
Show InChI InChI=1S/C29H25NO3/c31-29(32)24-16-9-10-20(19-24)18-23-15-7-8-17-25(23)28-30-26(21-11-3-1-4-12-21)27(33-28)22-13-5-2-6-14-22/h1-6,9-14,16-17,19,23H,7-8,15,18H2,(H,31,32)/t23-/m0/s1
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>3.00E+3n/an/an/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-PGF-2 binding to human prostanoid FP receptor


J Med Chem 48: 3103-6 (2005)


Article DOI: 10.1021/jm050085k
BindingDB Entry DOI: 10.7270/Q2XD116M
More data for this
Ligand-Target Pair
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