Reaction Details |
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Target | Dipeptidyl peptidase 2 |
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Ligand | BDBM11464 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_305450 (CHEMBL830125) |
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IC50 | 68985±n/a nM |
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Citation | Lu, IL; Lee, SJ; Tsu, H; Wu, SY; Kao, KH; Chien, CH; Chang, YY; Chen, YS; Cheng, JH; Chang, CN; Chen, TW; Chang, SP; Chen, X; Jiaang, WT Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors. Bioorg Med Chem Lett15:3271-5 (2005) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Dipeptidyl peptidase 2 |
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Name: | Dipeptidyl peptidase 2 |
Synonyms: | DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase |
Type: | Protein |
Mol. Mass.: | 54339.29 |
Organism: | Homo sapiens (Human) |
Description: | Q9UHL4 |
Residue: | 492 |
Sequence: | MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
QPALRGGPRLSL
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BDBM11464 |
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n/a |
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Name | BDBM11464 |
Synonyms: | (2S,3S)-2-amino-3-methyl-1-(1,3-thiazolidin-3-yl)pentan-1-one | BMCL15687 Compound 4 | CHEMBL98408 | P32-98 | thiazolidide 2 |
Type | Small organic molecule |
Emp. Form. | C9H18N2OS |
Mol. Mass. | 202.317 |
SMILES | CC[C@H](C)[C@H](N)C(=O)N1CCSC1 |r| |
Structure |
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