| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50596502 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2220576 (CHEMBL5133910) |
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| EC50 | 49±n/a nM |
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| Citation |  Kato, T; Ohara, T; Suzuki, N; Muto, S; Tokuyama, R; Mizutani, M; Fukasawa, H; Matsumura, KI; Itai, A Discovery and structure-based design of a new series of potent and selective PPAR? agonists utilizing a virtual screening method. Bioorg Med Chem Lett59:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NUC1 | Nr1c2 | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARD_MOUSE | Pparb | Ppard |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49719.14 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1288931 |
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| Residue: | 440 |
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| Sequence: | MEQPQEETPEAREEEKEEVAMGDGAPELNGGPEHTLPSSSCADLSQNSSPSSLLDQLQMG
CDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCDRICKIQKKN
RNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQHNPQLADLKAFSKH
IYNAYLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEI
SVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKD
GLLVANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDR
PGLMNVPQVEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLK
KTESETLLHPLLQEIYKDMY
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| BDBM50596502 |
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| n/a |
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| Name | BDBM50596502 |
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| Synonyms: | CHEMBL5180328 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22Cl2N2O3S |
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| Mol. Mass. | 465.393 |
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| SMILES | OC(=O)Cc1ccc(Cl)c(OCCC2CCN(CC2)c2nc3ccc(Cl)cc3s2)c1 |
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| Structure | 
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