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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Nociceptin receptor | ||
| Ligand | BDBM50173264 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_321553 (CHEMBL881967) | ||
| IC50 | 100±n/a nM | ||
| Citation |  Bignan, GC; Battista, K; Connolly, PJ; Orsini, MJ; Liu, J; Middleton, SA; Reitz, AB Preparation of 3-spirocyclic indolin-2-ones as ligands for the ORL-1 receptor. Bioorg Med Chem Lett15:5022-6 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Nociceptin receptor | |||
| Name: | Nociceptin receptor | ||
| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 40702.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P41146 | ||
| Residue: | 370 | ||
| Sequence: |
| ||
| BDBM50173264 | |||
| n/a | |||
| Name | BDBM50173264 | ||
| Synonyms: | CHEMBL197942 | methyl 2-[1'-[4-(tert-butyl)cyclohexylmethyl]-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H38N2O3 | ||
| Mol. Mass. | 426.5915 | ||
| SMILES | COC(=O)CN1C(=O)C2(CCN(CC3CCC(CC3)C(C)(C)C)CC2)c2ccccc12 |(5.06,2.61,;3.55,2.29,;2.53,3.43,;2.99,4.89,;1.03,3.1,;.54,1.65,;1.45,.39,;2.99,.39,;.54,-.87,;2.06,-1.17,;2.53,-2.64,;1.5,-3.79,;1.97,-5.26,;.92,-6.4,;-.58,-6.07,;-1.6,-7.19,;-1.14,-8.66,;.36,-9.01,;1.41,-7.86,;-2.19,-9.81,;-1.07,-10.88,;-3.28,-8.73,;-3.28,-10.9,;-.02,-3.46,;-.48,-2.01,;-.93,-.38,;-2.26,-1.15,;-3.59,-.38,;-3.59,1.16,;-2.26,1.93,;-.93,1.16,)| | ||
| Structure | 
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