Compile Data Set for Download or QSAR

Found 250 hits with Last Name = 'bignan' and Initial = 'gc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50185799 (1-(1,2-dihydroacenaphthylen-1-yl)-4-(1-methyl-1H-p...) Show SMILES Cn1cc(C2CCN(CC2O)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C25H25N3O/c1-27-14-21(19-9-4-11-26-25(19)27)18-10-12-28(15-23(18)29)22-13-17-7-2-5-16-6-3-8-20(22)24(16)17/h2-9,11,14,18,22-23,29H,10,12-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185800 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES C1C(N2CCC(CC2)c2c[nH]c3ncccc23)c2cccc3cccc1c23 Show InChI InChI=1S/C24H23N3/c1-4-17-5-2-7-20-22(14-18(6-1)23(17)20)27-12-9-16(10-13-27)21-15-26-24-19(21)8-3-11-25-24/h1-8,11,15-16,22H,9-10,12-14H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185805 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Fc1ccc2[nH]cc(C3CCN(CC3)C3Cc4cccc5cccc3c45)c2c1 Show InChI InChI=1S/C25H23FN2/c26-19-7-8-23-21(14-19)22(15-27-23)16-9-11-28(12-10-16)24-13-18-5-1-3-17-4-2-6-20(24)25(17)18/h1-8,14-16,24,27H,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from ORL1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185813 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C25H23FN2/c26-19-7-8-20-22(15-27-23(20)14-19)16-9-11-28(12-10-16)24-13-18-5-1-3-17-4-2-6-21(24)25(17)18/h1-8,14-16,24,27H,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185811 (7-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C25H23ClN2/c26-22-9-3-7-19-21(15-27-25(19)22)16-10-12-28(13-11-16)23-14-18-6-1-4-17-5-2-8-20(23)24(17)18/h1-9,15-16,23,27H,10-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from ORL1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185788 ((2R)-1-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperi...) Show SMILES CN(C)C[C@@H](O)Cn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2ccc(F)cc12 Show InChI InChI=1S/C30H34FN3O/c1-32(2)17-24(35)18-34-19-27(25-10-9-23(31)16-29(25)34)20-11-13-33(14-12-20)28-15-22-7-3-5-21-6-4-8-26(28)30(21)22/h3-10,16,19-20,24,28,35H,11-15,17-18H2,1-2H3/t24-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185803 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Cn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C25H25N3/c1-27-16-22(20-9-4-12-26-25(20)27)17-10-13-28(14-11-17)23-15-19-7-2-5-18-6-3-8-21(23)24(18)19/h2-9,12,16-17,23H,10-11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185812 (2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4...) Show SMILES OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C26H27N3O/c30-15-14-29-17-23(21-8-3-11-27-26(21)29)18-9-12-28(13-10-18)24-16-20-6-1-4-19-5-2-7-22(24)25(19)20/h1-8,11,17-18,24,30H,9-10,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185786 (3-(1-(1,2-dihydroacenaphthylen-1-yl)-1,2,3,6-tetra...) Show SMILES Fc1ccc2c(c[nH]c2c1)C1=CCN(CC1)C1Cc2cccc3cccc1c23 |t:12| Show InChI InChI=1S/C25H21FN2/c26-19-7-8-20-22(15-27-23(20)14-19)16-9-11-28(12-10-16)24-13-18-5-1-3-17-4-2-6-21(24)25(17)18/h1-9,14-15,24,27H,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185799 (1-(1,2-dihydroacenaphthylen-1-yl)-4-(1-methyl-1H-p...) Show SMILES Cn1cc(C2CCN(CC2O)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C25H25N3O/c1-27-14-21(19-9-4-11-26-25(19)27)18-10-12-28(15-23(18)29)22-13-17-7-2-5-16-6-3-8-20(22)24(16)17/h2-9,11,14,18,22-23,29H,10,12-13,15H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185810 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fluoro-1H...) Show SMILES Fc1ccc2[nH]cc(C3CCN(CC4CCCCCCC4)CC3)c2c1 Show InChI InChI=1S/C22H31FN2/c23-19-8-9-22-20(14-19)21(15-24-22)18-10-12-25(13-11-18)16-17-6-4-2-1-3-5-7-17/h8-9,14-15,17-18,24H,1-7,10-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185792 (3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...) Show SMILES Clc1ccc2[nH]cc(C3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C20H21ClN2/c21-17-6-7-20-18(12-17)19(13-22-20)16-8-10-23(11-9-16)14-15-4-2-1-3-5-15/h1-7,12-13,16,22H,8-11,14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185811 (7-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C25H23ClN2/c26-22-9-3-7-19-21(15-27-25(19)22)16-10-12-28(13-11-16)23-14-18-6-1-4-17-5-2-8-20(23)24(17)18/h1-9,15-16,23,27H,10-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185810 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fluoro-1H...) Show SMILES Fc1ccc2[nH]cc(C3CCN(CC4CCCCCCC4)CC3)c2c1 Show InChI InChI=1S/C22H31FN2/c23-19-8-9-22-20(14-19)21(15-24-22)18-10-12-25(13-11-18)16-17-6-4-2-1-3-5-7-17/h8-9,14-15,17-18,24H,1-7,10-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185808 (3-(1-(4-phenoxybenzyl)piperidin-4-yl)-1H-pyrrolo[2...) Show SMILES C(N1CCC(CC1)c1c[nH]c2ncccc12)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H25N3O/c1-2-5-21(6-3-1)29-22-10-8-19(9-11-22)18-28-15-12-20(13-16-28)24-17-27-25-23(24)7-4-14-26-25/h1-11,14,17,20H,12-13,15-16,18H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185792 (3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...) Show SMILES Clc1ccc2[nH]cc(C3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C20H21ClN2/c21-17-6-7-20-18(12-17)19(13-22-20)16-8-10-23(11-9-16)14-15-4-2-1-3-5-15/h1-7,12-13,16,22H,8-11,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185807 (5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C23H33ClN2/c1-17-23(21-15-20(24)9-10-22(21)25-17)19-11-13-26(14-12-19)16-18-7-5-3-2-4-6-8-18/h9-10,15,18-19,25H,2-8,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185802 (3-(1-(naphthalen-1-ylmethyl)piperidin-4-yl)-1H-pyr...) Show SMILES C(N1CCC(CC1)c1c[nH]c2ncccc12)c1cccc2ccccc12 Show InChI InChI=1S/C23H23N3/c1-2-8-20-17(5-1)6-3-7-19(20)16-26-13-10-18(11-14-26)22-15-25-23-21(22)9-4-12-24-23/h1-9,12,15,18H,10-11,13-14,16H2,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185800 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES C1C(N2CCC(CC2)c2c[nH]c3ncccc23)c2cccc3cccc1c23 Show InChI InChI=1S/C24H23N3/c1-4-17-5-2-7-20-22(14-18(6-1)23(17)20)27-12-9-16(10-13-27)21-15-26-24-19(21)8-3-11-25-24/h1-8,11,15-16,22H,9-10,12-14H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185794 (5-fluoro-3-(1-(naphthalen-1-ylmethyl)piperidin-4-y...) Show SMILES Fc1ccc2[nH]cc(C3CCN(Cc4cccc5ccccc45)CC3)c2c1 Show InChI InChI=1S/C24H23FN2/c25-20-8-9-24-22(14-20)23(15-26-24)18-10-12-27(13-11-18)16-19-6-3-5-17-4-1-2-7-21(17)19/h1-9,14-15,18,26H,10-13,16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185805 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Fc1ccc2[nH]cc(C3CCN(CC3)C3Cc4cccc5cccc3c45)c2c1 Show InChI InChI=1S/C25H23FN2/c26-19-7-8-23-21(14-19)22(15-27-23)16-9-11-28(12-10-16)24-13-18-5-1-3-17-4-2-6-20(24)25(17)18/h1-8,14-16,24,27H,9-13H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185809 (3-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-chlo...) Show SMILES Clc1ccc2[nH]cc(C3=CCN(Cc4ccccc4)CC3)c2c1 |t:8| Show InChI InChI=1S/C20H19ClN2/c21-17-6-7-20-18(12-17)19(13-22-20)16-8-10-23(11-9-16)14-15-4-2-1-3-5-15/h1-8,12-13,22H,9-11,14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185812 (2-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4...) Show SMILES OCCn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C26H27N3O/c30-15-14-29-17-23(21-8-3-11-27-26(21)29)18-9-12-28(13-10-18)24-16-20-6-1-4-19-5-2-7-22(24)25(19)20/h1-8,11,17-18,24,30H,9-10,12-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185806 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[...) Show SMILES C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H31N3/c1-2-4-7-17(8-5-3-1)16-24-13-10-18(11-14-24)20-15-23-21-19(20)9-6-12-22-21/h6,9,12,15,17-18H,1-5,7-8,10-11,13-14,16H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185796 (5-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C26H25ClN2/c1-16-25(22-15-20(27)8-9-23(22)28-16)18-10-12-29(13-11-18)24-14-19-6-2-4-17-5-3-7-21(24)26(17)19/h2-9,15,18,24,28H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185807 (5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C23H33ClN2/c1-17-23(21-15-20(24)9-10-22(21)25-17)19-11-13-26(14-12-19)16-18-7-5-3-2-4-6-8-18/h9-10,15,18-19,25H,2-8,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185802 (3-(1-(naphthalen-1-ylmethyl)piperidin-4-yl)-1H-pyr...) Show SMILES C(N1CCC(CC1)c1c[nH]c2ncccc12)c1cccc2ccccc12 Show InChI InChI=1S/C23H23N3/c1-2-8-20-17(5-1)6-3-7-19(20)16-26-13-10-18(11-14-26)22-15-25-23-21(22)9-4-12-24-23/h1-9,12,15,18H,10-11,13-14,16H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185795 (5-chloro-2-methyl-3-(1-(naphthalen-1-ylmethyl)pipe...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(Cc2cccc3ccccc23)CC1 Show InChI InChI=1S/C25H25ClN2/c1-17-25(23-15-21(26)9-10-24(23)27-17)19-11-13-28(14-12-19)16-20-7-4-6-18-5-2-3-8-22(18)20/h2-10,15,19,27H,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185788 ((2R)-1-(3-(1-(1,2-dihydroacenaphthylen-1-yl)piperi...) Show SMILES CN(C)C[C@@H](O)Cn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2ccc(F)cc12 Show InChI InChI=1S/C30H34FN3O/c1-32(2)17-24(35)18-34-19-27(25-10-9-23(31)16-29(25)34)20-11-13-33(14-12-20)28-15-22-7-3-5-21-6-4-8-26(28)30(21)22/h3-10,16,19-20,24,28,35H,11-15,17-18H2,1-2H3/t24-,28?/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185794 (5-fluoro-3-(1-(naphthalen-1-ylmethyl)piperidin-4-y...) Show SMILES Fc1ccc2[nH]cc(C3CCN(Cc4cccc5ccccc45)CC3)c2c1 Show InChI InChI=1S/C24H23FN2/c25-20-8-9-24-22(14-20)23(15-26-24)18-10-12-27(13-11-18)16-19-6-3-5-17-4-1-2-7-21(17)19/h1-9,14-15,18,26H,10-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185802 (3-(1-(naphthalen-1-ylmethyl)piperidin-4-yl)-1H-pyr...) Show SMILES C(N1CCC(CC1)c1c[nH]c2ncccc12)c1cccc2ccccc12 Show InChI InChI=1S/C23H23N3/c1-2-8-20-17(5-1)6-3-7-19(20)16-26-13-10-18(11-14-26)22-15-25-23-21(22)9-4-12-24-23/h1-9,12,15,18H,10-11,13-14,16H2,(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185794 (5-fluoro-3-(1-(naphthalen-1-ylmethyl)piperidin-4-y...) Show SMILES Fc1ccc2[nH]cc(C3CCN(Cc4cccc5ccccc45)CC3)c2c1 Show InChI InChI=1S/C24H23FN2/c25-20-8-9-24-22(14-20)23(15-26-24)18-10-12-27(13-11-18)16-19-6-3-5-17-4-1-2-7-21(17)19/h1-9,14-15,18,26H,10-13,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185795 (5-chloro-2-methyl-3-(1-(naphthalen-1-ylmethyl)pipe...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(Cc2cccc3ccccc23)CC1 Show InChI InChI=1S/C25H25ClN2/c1-17-25(23-15-21(26)9-10-24(23)27-17)19-11-13-28(14-12-19)16-20-7-4-6-18-5-2-3-8-22(18)20/h2-10,15,19,27H,11-14,16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185813 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Fc1ccc2c(c[nH]c2c1)C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C25H23FN2/c26-19-7-8-20-22(15-27-23(20)14-19)16-9-11-28(12-10-16)24-13-18-5-1-3-17-4-2-6-21(24)25(17)18/h1-8,14-16,24,27H,9-13H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185803 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Cn1cc(C2CCN(CC2)C2Cc3cccc4cccc2c34)c2cccnc12 Show InChI InChI=1S/C25H25N3/c1-27-16-22(20-9-4-12-26-25(20)27)17-10-13-28(14-11-17)23-15-19-7-2-5-18-6-3-8-21(23)24(18)19/h2-9,12,16-17,23H,10-11,13-15H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185789 ((R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fl...) Show SMILES CN(C)C[C@@H](O)Cn1cc(C2CCN(CC3CCCCCCC3)CC2)c2cc(F)ccc12 Show InChI InChI=1S/C27H42FN3O/c1-29(2)18-24(32)19-31-20-26(25-16-23(28)10-11-27(25)31)22-12-14-30(15-13-22)17-21-8-6-4-3-5-7-9-21/h10-11,16,20-22,24,32H,3-9,12-15,17-19H2,1-2H3/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185809 (3-(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-chlo...) Show SMILES Clc1ccc2[nH]cc(C3=CCN(Cc4ccccc4)CC3)c2c1 |t:8| Show InChI InChI=1S/C20H19ClN2/c21-17-6-7-20-18(12-17)19(13-22-20)16-8-10-23(11-9-16)14-15-4-2-1-3-5-15/h1-8,12-13,22H,9-11,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185810 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fluoro-1H...) Show SMILES Fc1ccc2[nH]cc(C3CCN(CC4CCCCCCC4)CC3)c2c1 Show InChI InChI=1S/C22H31FN2/c23-19-8-9-22-20(14-19)21(15-24-22)18-10-12-25(13-11-18)16-17-6-4-2-1-3-5-7-17/h8-9,14-15,17-18,24H,1-7,10-13,16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185792 (3-(1-benzylpiperidin-4-yl)-5-chloro-1H-indole | CH...) Show SMILES Clc1ccc2[nH]cc(C3CCN(Cc4ccccc4)CC3)c2c1 Show InChI InChI=1S/C20H21ClN2/c21-17-6-7-20-18(12-17)19(13-22-20)16-8-10-23(11-9-16)14-15-4-2-1-3-5-15/h1-7,12-13,16,22H,8-11,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185798 (7-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C22H31ClN2/c23-21-10-6-9-19-20(15-24-22(19)21)18-11-13-25(14-12-18)16-17-7-4-2-1-3-5-8-17/h6,9-10,15,17-18,24H,1-5,7-8,11-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185807 (5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...) Show SMILES Cc1[nH]c2ccc(Cl)cc2c1C1CCN(CC2CCCCCCC2)CC1 Show InChI InChI=1S/C23H33ClN2/c1-17-23(21-15-20(24)9-10-22(21)25-17)19-11-13-26(14-12-19)16-18-7-5-3-2-4-6-8-18/h9-10,15,18-19,25H,2-8,11-14,16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185797 (1-((R)-3-amino-2-hydroxypropyl)-3-(1-(1,2-dihydroa...) Show SMILES NC[C@@H](O)Cn1cc(C2=CCN(CC2)C2Cc3cccc4cccc2c34)c2cc(ccc12)C#N |t:8| Show InChI InChI=1S/C29H28N4O/c30-15-19-7-8-27-25(13-19)26(18-33(27)17-23(34)16-31)20-9-11-32(12-10-20)28-14-22-5-1-3-21-4-2-6-24(28)29(21)22/h1-9,13,18,23,28,34H,10-12,14,16-17,31H2/t23-,28?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185805 (3-(1-(1,2-dihydroacenaphthylen-1-yl)piperidin-4-yl...) Show SMILES Fc1ccc2[nH]cc(C3CCN(CC3)C3Cc4cccc5cccc3c45)c2c1 Show InChI InChI=1S/C25H23FN2/c26-19-7-8-23-21(14-19)22(15-27-23)16-9-11-28(12-10-16)24-13-18-5-1-3-17-4-2-6-20(24)25(17)18/h1-8,14-16,24,27H,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185789 ((R)-1-(3-(1-(cyclooctylmethyl)piperidin-4-yl)-5-fl...) Show SMILES CN(C)C[C@@H](O)Cn1cc(C2CCN(CC3CCCCCCC3)CC2)c2cc(F)ccc12 Show InChI InChI=1S/C27H42FN3O/c1-29(2)18-24(32)19-31-20-26(25-16-23(28)10-11-27(25)31)22-12-14-30(15-13-22)17-21-8-6-4-3-5-7-9-21/h10-11,16,20-22,24,32H,3-9,12-15,17-19H2,1-2H3/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50185806 (3-(1-(cyclooctylmethyl)piperidin-4-yl)-1H-pyrrolo[...) Show SMILES C(C1CCCCCCC1)N1CCC(CC1)c1c[nH]c2ncccc12 Show InChI InChI=1S/C21H31N3/c1-2-4-7-17(8-5-3-1)16-24-13-10-18(11-14-24)20-15-23-21-19(20)9-6-12-22-21/h6,9,12,15,17-18H,1-5,7-8,10-11,13-14,16H2,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50185811 (7-chloro-3-(1-(1,2-dihydroacenaphthylen-1-yl)piper...) Show SMILES Clc1cccc2c(c[nH]c12)C1CCN(CC1)C1Cc2cccc3cccc1c23 Show InChI InChI=1S/C25H23ClN2/c26-22-9-3-7-19-21(15-27-25(19)22)16-10-12-28(13-11-16)23-14-18-6-1-4-17-5-2-8-20(23)24(17)18/h1-9,15-16,23,27H,10-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells				Bioorg Med Chem Lett 16: 3524-8 (2006) Article DOI: 10.1016/j.bmcl.2006.03.094 BindingDB Entry DOI: 10.7270/Q2VT1RQJ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 250 total )  |  Next  |  Last  >>

Jump to: