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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50176405 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_333261 (CHEMBL859080) | ||
| Ki | >10000±n/a nM | ||
| Citation |  Carpino, PA; Griffith, DA; Sakya, S; Dow, RL; Black, SC; Hadcock, JR; Iredale, PA; Scott, DO; Fichtner, MW; Rose, CR; Day, R; Dibrino, J; Butler, M; Debartolo, DB; Dutcher, D; Gautreau, D; Lizano, JS; O'connor, RE; Sands, MA; Kelly-Sullivan, D; Ward, KM New bicyclic cannabinoid receptor-1 (CB1-R) antagonists. Bioorg Med Chem Lett16:731-6 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
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| BDBM50176405 | |||
| n/a | |||
| Name | BDBM50176405 | ||
| Synonyms: | 3-(2-chlorophenyl)-2-(4-chlorophenyl)-6-cyclohexyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | CHEMBL201929 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H20Cl2N4O | ||
| Mol. Mass. | 439.337 | ||
| SMILES | Clc1ccc(cc1)-n1nc2c(ncn(C3CCCCC3)c2=O)c1-c1ccccc1Cl |(7.43,-6.25,;8.19,-4.92,;7.42,-3.58,;8.19,-2.25,;9.73,-2.25,;10.5,-3.57,;9.74,-4.91,;10.49,-.9,;12.02,-.74,;12.33,.77,;11,1.54,;11.01,3.07,;12.33,3.85,;13.66,3.07,;15,3.84,;16.33,3.05,;17.66,3.81,;17.68,5.35,;16.35,6.13,;15,5.37,;13.66,1.53,;15,.76,;9.86,.5,;8.35,.81,;7.33,-.33,;5.83,-.02,;5.35,1.45,;6.37,2.59,;7.87,2.28,;8.9,3.42,)| | ||
| Structure | 
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