| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50599917 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2232050 (CHEMBL5145822) |
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| Ki | 9.0±n/a nM |
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| Citation |  Juza, R; Vojtechova, I; Stefkova-Mazochova, K; Dehaen, W; Petrasek, T; Prchal, L; Kobrlova, T; Janousek, J; Vlcek, P; Mezeiova, E; Svozil, D; Karasova, JZ; Pejchal, J; Stark, H; Satala, G; Bojarski, AJ; Kubacka, M; Mogilski, S; Randakova, A; Musilek, K; Soukup, O; Korabecny, J Novel D Eur J Med Chem232:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50599917 |
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| n/a |
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| Name | BDBM50599917 |
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| Synonyms: | CHEMBL5172819 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N4O3 |
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| Mol. Mass. | 408.4934 |
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| SMILES | O=C(N1CCN(CCCCOc2ccc3CCC(=O)Nc3c2)CC1)c1ccccn1 |
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| Structure | 
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