| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix metalloproteinase-15 |
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| Ligand | BDBM50180601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_330172 (CHEMBL863525) |
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| IC50 | 13940±n/a nM |
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| Citation |  Ma, D; Jiang, Y; Chen, F; Gong, LK; Ding, K; Xu, Y; Wang, R; Ge, A; Ren, J; Li, J; Li, J; Ye, Q Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted gamma-keto carboxylic acids. J Med Chem49:456-8 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix metalloproteinase-15 |
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| Name: | Matrix metalloproteinase-15 |
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| Synonyms: | MMP-15 | MMP15 | MMP15_HUMAN | MT-MMP 2 | MT2-MMP | MT2MMP | MTMMP2 | Matrix metalloproteinase 15 | Matrix metalloproteinase-15 | Membrane-type matrix metalloproteinase 2 | Membrane-type-2 matrix metalloproteinase | SMCP-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 75814.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_106793 |
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| Residue: | 669 |
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| Sequence: | MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLY
GYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVR
VKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQ
EVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEP
WTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQ
QLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATE
RPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDIS
AAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFF
FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNE
RLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGD
FGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLY
CKRSLQEWV
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| BDBM50180601 |
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| n/a |
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| Name | BDBM50180601 |
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| Synonyms: | 3-(4-(2-phenylethynyl)benzoyl)pentanoic acid | CHEMBL202875 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18O3 |
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| Mol. Mass. | 306.3551 |
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| SMILES | CCC(CC(O)=O)C(=O)c1ccc(cc1)C#Cc1ccccc1 |
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| Structure | 
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