| Reaction Details |
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 | Report a problem with these data |
| Target | Lutropin-choriogonadotropic hormone receptor |
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| Ligand | BDBM50189774 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_367601 (CHEMBL864095) |
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| EC50 | 1900±n/a nM |
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| Citation |  Moore, S; Jaeschke, H; Kleinau, G; Neumann, S; Costanzi, S; Jiang, JK; Childress, J; Raaka, BM; Colson, A; Paschke, R; Krause, G; Thomas, CJ; Gershengorn, MC Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns. J Med Chem49:3888-96 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lutropin-choriogonadotropic hormone receptor |
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| Name: | Lutropin-choriogonadotropic hormone receptor |
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| Synonyms: | LCGR | LGR2 | LH/CG-R | LHCGR | LHR | LHRHR | LSH-R | LSHR_HUMAN | Luteinizing hormone receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78662.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_562598 |
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| Residue: | 699 |
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| Sequence: | MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP
VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI
NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK
LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY
GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF
SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD
FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS
QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL
RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF
IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT
VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT
SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
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| BDBM50189774 |
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| n/a |
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| Name | BDBM50189774 |
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| Synonyms: | CHEMBL378091 | N-tert-butyl-5-amino-4-(3-hydroxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N4O2S2 |
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| Mol. Mass. | 388.507 |
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| SMILES | CSc1nc(-c2cccc(O)c2)c2c(N)c(sc2n1)C(=O)NC(C)(C)C |
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| Structure | 
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