Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253660 (2-{3-(2-Amino-ethyl-guanidino)-4-[2-amino-3-(4-flu...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50119368 ((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cells | Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50198573 ((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50198574 ((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells | Bioorg Med Chem Lett 17: 819-22 (2007) Article DOI: 10.1016/j.bmcl.2006.10.052 BindingDB Entry DOI: 10.7270/Q2736QKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253738 (CHEMBL449131 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203064 ((S)-4-(4-bromophenethyl)-1-(6-((diethylamino)-meth...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50198574 ((S)-4-(4-chlorophenethyl)-1-(6-((diethylamino)-met...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253736 (CHEMBL506272 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253748 ((2S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253745 ((S)-2-((S)-4-((R)-3-(4-Fluorophenyl)-2-(2-(methyla...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253749 (CHEMBL506762 | N-((1R)-1-[(4-Fluorophenyl)methyl]-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253750 ((3S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253739 (CHEMBL463047 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253746 ((2S)-N-Methyl-2-[(3S)-4-(N-methyl-L-alanyl-4-fluor...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203054 (4'-fluoro-biphenyl-4-carboxylic acid [2-(4-dimethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192169 ((R)-3,5-dimethoxy-N-(1-(naphthalen-2-ylmethyl)pyrr...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253733 (2-{4-[2-Acetylamino-3-(4-fluoro-phenyl)-propionyl]...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192189 (3,4,5-trifluoro-N-(1-(naphthalen-2-ylmethyl)piperi...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253741 ((S)-2-((S)-4-((R)-2-Acetamido-3-amino propan-(4-fl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203063 ((S)-4-(3-fluorophenethyl)-1-(6-((diethylamino)-met...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50189008 ((S)-2-((S)-4-((R)-2-amino-3-(4-fluorophenyl)propan...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50200748 (1-(4-(piperidin-1-ylmethyl)phenethyl)-4-phenethylp...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells | Bioorg Med Chem Lett 17: 657-61 (2007) Article DOI: 10.1016/j.bmcl.2006.10.096 BindingDB Entry DOI: 10.7270/Q2QR4WS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50200748 (1-(4-(piperidin-1-ylmethyl)phenethyl)-4-phenethylp...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253743 (1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50168507 ((E)-N-(1-cinnamylpiperidin-4-yl)-3,5-dimethoxybenz...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203055 ((S)-4-(2-fluorophenethyl)-1-(6-((diethylamino)-met...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192178 (3,5-dimethoxy-N-((3R)-1-(1-(naphthalen-2-yl)ethyl)...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253747 ((2S)-N-((1R)-1-[(4-Fluorophenyl)methyl]-2-{(2S)-4-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192174 (4-fluoro-3-methoxy-N-(1-(naphthalen-2-ylmethyl)pip...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253735 ((2S)-2-((3S)-4-{4-Fluoro-N-[(methyloxy)acetyl]-D-p...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253744 (1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50200742 (7-(4-fluorophenethyl)-2-(4-(piperidin-1-ylmethyl)p...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells | Bioorg Med Chem Lett 17: 657-61 (2007) Article DOI: 10.1016/j.bmcl.2006.10.096 BindingDB Entry DOI: 10.7270/Q2QR4WS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50198573 ((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of binding to MCH-R1 | Bioorg Med Chem Lett 17: 819-22 (2007) Article DOI: 10.1016/j.bmcl.2006.10.052 BindingDB Entry DOI: 10.7270/Q2736QKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203059 ((S)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydro...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192163 ((R,E)-N-(1-cinnamylpyrrolidin-3-yl)-3,5-dimethoxyb...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocyte-stimulating hormone receptor (Homo sapiens (Human)) | BDBM50253749 (CHEMBL506762 | N-((1R)-1-[(4-Fluorophenyl)methyl]-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192161 (3,4-difluoro-N-(1-(naphthalen-2-ylmethyl)piperidin...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253734 (CHEMBL507876 | N-((1R)-1-[(4-Fluorophenyl)methyl]-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203061 ((S)-4-(3-chlorophenethyl)-1-(6-((diethylamino)-met...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203057 (4'-fluoro-biphenyl-4-carboxylic acid [2-(4-dimethy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50200744 (CHEMBL408198 | N-(3-fluorophenyl)-4-oxo-5-(4-(pipe...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells | Bioorg Med Chem Lett 17: 657-61 (2007) Article DOI: 10.1016/j.bmcl.2006.10.096 BindingDB Entry DOI: 10.7270/Q2QR4WS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192162 (3,5-dimethoxy-N-((3R)-1-((E)-4-phenylbut-3-en-2-yl...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50200745 (7-(4-fluorophenyl)-2-(4-(piperidin-1-ylmethyl)phen...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells | Bioorg Med Chem Lett 17: 657-61 (2007) Article DOI: 10.1016/j.bmcl.2006.10.096 BindingDB Entry DOI: 10.7270/Q2QR4WS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50372555 (CHEMBL272099) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cells | Bioorg Med Chem Lett 18: 1223-8 (2008) Article DOI: 10.1016/j.bmcl.2007.11.109 BindingDB Entry DOI: 10.7270/Q2TM7BZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50203056 (CHEMBL388181 | N-(4'-fluoro-biphenyl-4-yl)-3-(4-pi...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay | Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192160 (3,5-dimethoxy-N-(1-(1-(naphthalen-2-yl)ethyl)piper...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50253742 (1-Amino-N-((1R)-1-[(4-fluorophenyl)methyl]-2-{(2S)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells | J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192177 (3,5-dimethoxy-N-(1-(naphthalen-2-ylmethyl)piperidi...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192165 (3-methoxy-N-(1-(naphthalen-2-ylmethyl)piperidin-4-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM50192182 (CHEMBL214778 | N-(1-((6-fluoronaphthalen-2-yl)meth...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Binding activity against human MCH-R1 | Bioorg Med Chem Lett 16: 5445-50 (2006) Article DOI: 10.1016/j.bmcl.2006.07.053 BindingDB Entry DOI: 10.7270/Q2CR5T0F | |||||||||||
More data for this Ligand-Target Pair |
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