| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50190098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_393314 (CHEMBL911524) |
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| Ki | 231±n/a nM |
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| Citation |  Su, J; Tang, H; McKittrick, BA; Burnett, DA; Zhang, H; Smith-Torhan, A; Fawzi, A; Lachowicz, J Modification of the clozapine structure by parallel synthesis. Bioorg Med Chem Lett16:4548-53 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50190098 |
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| n/a |
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| Name | BDBM50190098 |
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| Synonyms: | CHEMBL214503 | N-[2-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-2-iodo-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23ClIN5O |
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| Mol. Mass. | 571.84 |
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| SMILES | CN1CCN(CC1)C1=Nc2ccccc2N(NC(=O)c2ccccc2I)c2ccc(Cl)cc12 |t:8| |
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| Structure | 
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