| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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| Ligand | BDBM50190549 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_373622 (CHEMBL869762) |
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| Ki | 5700±n/a nM |
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| Citation |  Nguyen, C; Ruda, GF; Schipani, A; Kasinathan, G; Leal, I; Musso-Buendia, A; Kaiser, M; Brun, R; Ruiz-Pérez, LM; Sahlberg, BL; Johansson, NG; Gonzalez-Pacanowska, D; Gilbert, IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem49:4183-95 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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| Name: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial |
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| Synonyms: | DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase |
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| Type: | Enzyme |
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| Mol. Mass.: | 26574.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P33316 |
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| Residue: | 252 |
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| Sequence: | MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSA
GRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLS
EHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKH
FIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTE
RGSGGFGSTGKN
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| BDBM50190549 |
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| n/a |
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| Name | BDBM50190549 |
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| Synonyms: | 1-[4-hydroxy-3-(tritylaminomethyl)butyl]uracil | CHEMBL378101 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29N3O3 |
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| Mol. Mass. | 455.5482 |
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| SMILES | OCC(CCn1ccc(=O)[nH]c1=O)CNC(c1ccccc1)(c1ccccc1)c1ccccc1 |
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| Structure | 
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