| Reaction Details |
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 | Report a problem with these data |
| Target | cGMP-dependent protein kinase |
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| Ligand | BDBM50195444 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_424969 (CHEMBL910725) |
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| IC50 | 0.1±n/a nM |
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| Citation |  Feng, D; Fisher, M; Liang, GB; Qian, X; Brown, C; Gurnett, A; Leavitt, PS; Liberator, PA; Mathew, J; Misura, A; Samaras, S; Tamas, T; Schmatz, DM; Wyvratt, M; Biftu, T Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents. Bioorg Med Chem Lett16:5978-81 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| cGMP-dependent protein kinase |
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| Name: | cGMP-dependent protein kinase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 112911.27 |
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| Organism: | Eimeria tenella |
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| Description: | ChEMBL_469577 |
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| Residue: | 1003 |
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| Sequence: | MGACSSKAQHQTRDPEPREQQAAQEQKSTGPSGAPNDAPAPAEAERKMSGSSATAPKGEM
PTASTGTPEQQQQQQQQQQQQQEQQQHPEHQQSEKQQQHGEEQQQERKPSQQQQNEEAAA
PHKHGGERKVQKAIKQQEDTQAEDARLLGHLEKREKTPSDLSLIRDSLSTNLVCSSLNDA
EVEALANAVEFFTFKKGDVVTKQGESGSYFFIVHSGEFEVIVNDKVVNKILTGQAFGEIS
LIHNSARTATIKTLSEDAALWGVQRQVFRETLKQLSSRNFAENRQFLASVKFFEMLTEAQ
KNVITNALVVQSFQPGQAIVKEGEKGDVLYILKSGKALVSIKNKEVRVLQRGEYFGERAL
LYDEPRSATITAEEPTVCVSIGRDLLDRVLGNLQHVLFRNIMLEALQQSKVFASFPTEQL
SRLIGSVVVKDYPENYIILDRENRTRASASALFSAQGVRFFFVLEGEVSVFAYKDKSSSS
SSSSSSSSSSSSAEGEMELHLIDTLKRGQAFGDEYVLSPNKPFAHCVKSNGPTKLALLTA
SALTATLGGQDIDETLDYNNKLAITKKMYIFRYLSEQQTQTLIKAFKTVRYTQGESIIRE
GEIGSRFFIIKLGEVVILKGEKRVRTLGRHDYFGERALLHDERRSATVAANSPEVDLWVV
DKDVFLQIVKGPMLTHLEERIRMQDTKVEFKDLNVVRVVGRGTFGTVKLVQHIPTQMRYA
LKCVSRKSVVALNQQDHIRLEREIMAENDHPFIIRLVRTFRDKEFLYFLTELVTGGELYD
AIRKLGLLGRYQAQFYLASIVLAIEYLHERNIAYRDLKPENILLDSQGYVKLIDFGCAKK
MQGRAYTLVGTPHYMAPEVILGKGYTLTADTWAFGVCLYEFMCGPLPFGNDAEDQLEIFR
DILAGKLIFPHYVTDQDAINLMKRLLCRLPEVRIGCSINGYKDIKEHAFFSDFDWDRLAG
RDLSPPLLPKGEIYAEDAEEGGLDIEEDEGIELEDEYEWDKDF
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| BDBM50195444 |
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| n/a |
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| Name | BDBM50195444 |
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| Synonyms: | 2-(ethyl((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethyl)pyrimidin-4-yl)H-imidazo[1,2-a]pyridin-7-yl)methyl)amino)ethanol | CHEMBL221584 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H30FN5O |
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| Mol. Mass. | 495.5905 |
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| SMILES | CCN(CCO)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(n1)[C@@H](C)c1ccccc1 |
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| Structure | 
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