Found 204 hits with Last Name = 'misura' and Initial = 'a' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182369
(4-(2-(4-fluorophenyl)-7-(1-methylpiperidin-4-yl)H-...)Show SMILES CN1CCC(CC1)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C23H23FN6/c1-29-11-7-15(8-12-29)17-9-13-30-20(14-17)28-21(16-2-4-18(24)5-3-16)22(30)19-6-10-26-23(25)27-19/h2-6,9-10,13-15H,7-8,11-12H2,1H3,(H2,25,26,27) | UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168170
(3-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES NCCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H27FN4/c24-20-4-2-19(3-5-20)23-21(17-6-11-26-12-7-17)16-22(27-23)18-8-14-28(15-9-18)13-1-10-25/h2-7,11-12,16,18,27H,1,8-10,13-15,25H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0460 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182367
(4-(2-(4-fluorophenyl)-7-(piperidin-4-yl)H-imidazo[...)Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCNCC1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H21FN6/c23-17-3-1-15(2-4-17)20-21(18-7-11-26-22(24)27-18)29-12-8-16(13-19(29)28-20)14-5-9-25-10-6-14/h1-4,7-8,11-14,25H,5-6,9-10H2,(H2,24,26,27) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211814
(4-(2-(4-fluorophenyl)-7-((isopropylamino)methyl)H-...)Show SMILES CC(C)NCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN6/c1-19(2)32-18-21-14-16-36-26(17-21)35-27(23-9-11-24(30)12-10-23)28(36)25-13-15-31-29(34-25)33-20(3)22-7-5-4-6-8-22/h4-17,19-20,32H,18H2,1-3H3,(H,31,33,34)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211811
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(Nc2ccccc2)n1 Show InChI InChI=1S/C26H23FN6/c1-32(2)17-18-13-15-33-23(16-18)31-24(19-8-10-20(27)11-9-19)25(33)22-12-14-28-26(30-22)29-21-6-4-3-5-7-21/h3-16H,17H2,1-2H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374578
(CHEMBL401749)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CC2CNCCN2)CC1 |w:23.25| Show InChI InChI=1S/C25H30FN5/c26-21-3-1-20(2-4-21)25-23(18-5-9-27-10-6-18)15-24(30-25)19-7-13-31(14-8-19)17-22-16-28-11-12-29-22/h1-6,9-10,15,19,22,28-30H,7-8,11-14,16-17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211805
(4-(7-(((3-(dimethylamino)propyl)(methyl)amino)meth...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCCN(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H36FN7/c1-23(25-9-6-5-7-10-25)35-32-34-17-15-28(36-32)31-30(26-11-13-27(33)14-12-26)37-29-21-24(16-20-40(29)31)22-39(4)19-8-18-38(2)3/h5-7,9-17,20-21,23H,8,18-19,22H2,1-4H3,(H,34,35,36)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374594
(CHEMBL444009)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CCN2CCC2)CC1 Show InChI InChI=1S/C25H29FN4/c26-22-4-2-21(3-5-22)25-23(19-6-10-27-11-7-19)18-24(28-25)20-8-14-30(15-9-20)17-16-29-12-1-13-29/h2-7,10-11,18,20,28H,1,8-9,12-17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182359
(CHEMBL379059 | N-benzyl-4-(7-((dimethylamino)methy...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2)n1 Show InChI InChI=1S/C27H25FN6/c1-33(2)18-20-13-15-34-24(16-20)32-25(21-8-10-22(28)11-9-21)26(34)23-12-14-29-27(31-23)30-17-19-6-4-3-5-7-19/h3-16H,17-18H2,1-2H3,(H,29,30,31) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0810 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182359
(CHEMBL379059 | N-benzyl-4-(7-((dimethylamino)methy...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2ccccc2)n1 Show InChI InChI=1S/C27H25FN6/c1-33(2)18-20-13-15-34-24(16-20)32-25(21-8-10-22(28)11-9-21)26(34)23-12-14-29-27(31-23)30-17-19-6-4-3-5-7-19/h3-16H,17-18H2,1-2H3,(H,29,30,31) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.0810 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211820
(4-(7-(((2-(azetidin-1-yl)ethyl)(methyl)amino)methy...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCN3CCC3)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H34FN7/c1-23(25-7-4-3-5-8-25)35-32-34-15-13-28(36-32)31-30(26-9-11-27(33)12-10-26)37-29-21-24(14-18-40(29)31)22-38(2)19-20-39-16-6-17-39/h3-5,7-15,18,21,23H,6,16-17,19-20,22H2,1-2H3,(H,34,35,36)/t23-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195444
(2-(ethyl((2-(4-fluorophenyl)-3-(2-((S)-1-phenyleth...)Show SMILES CCN(CCO)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(n1)[C@@H](C)c1ccccc1 Show InChI InChI=1S/C30H30FN5O/c1-3-35(17-18-37)20-22-14-16-36-27(19-22)34-28(24-9-11-25(31)12-10-24)29(36)26-13-15-32-30(33-26)21(2)23-7-5-4-6-8-23/h4-16,19,21,37H,3,17-18,20H2,1-2H3/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211812
(4-(2-(4-fluorophenyl)-7-((isopropyl(methyl)amino)m...)Show SMILES CC(C)N(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C30H31FN6/c1-20(2)36(4)19-22-15-17-37-27(18-22)35-28(24-10-12-25(31)13-11-24)29(37)26-14-16-32-30(34-26)33-21(3)23-8-6-5-7-9-23/h5-18,20-21H,19H2,1-4H3,(H,32,33,34)/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211802
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCO)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C29H29FN6O/c1-20(22-6-4-3-5-7-22)32-29-31-14-12-25(33-29)28-27(23-8-10-24(30)11-9-23)34-26-18-21(13-15-36(26)28)19-35(2)16-17-37/h3-15,18,20,37H,16-17,19H2,1-2H3,(H,31,32,33)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182362
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C20H19FN6/c1-26(2)12-13-8-10-27-17(11-13)25-18(14-3-5-15(21)6-4-14)19(27)16-7-9-23-20(22)24-16/h3-11H,12H2,1-2H3,(H2,22,23,24) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195435
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethyl)py...)Show SMILES C[C@@H](c1ccccc1)c1nccc(n1)-c1c(nc2cc(CN(C)CCO)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C29H28FN5O/c1-20(22-6-4-3-5-7-22)29-31-14-12-25(32-29)28-27(23-8-10-24(30)11-9-23)33-26-18-21(13-15-35(26)28)19-34(2)16-17-36/h3-15,18,20,36H,16-17,19H2,1-2H3/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195439
(CHEMBL221636 | N-((2-(4-fluorophenyl)-3-(2-((S)-1-...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(n1)[C@@H](C)c1ccccc1 Show InChI InChI=1S/C29H28FN5/c1-4-34(3)19-21-15-17-35-26(18-21)33-27(23-10-12-24(30)13-11-23)28(35)25-14-16-31-29(32-25)20(2)22-8-6-5-7-9-22/h5-18,20H,4,19H2,1-3H3/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211803
(4-(7-((ethyl(methyl)amino)methyl)-2-(4-fluoropheny...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N[C@@H](C)c2ccccc2)n1 Show InChI InChI=1S/C29H29FN6/c1-4-35(3)19-21-15-17-36-26(18-21)34-27(23-10-12-24(30)13-11-23)28(36)25-14-16-31-29(33-25)32-20(2)22-8-6-5-7-9-22/h5-18,20H,4,19H2,1-3H3,(H,31,32,33)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182355
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CCCNc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C23H25FN6/c1-4-11-25-23-26-12-9-19(27-23)22-21(17-5-7-18(24)8-6-17)28-20-14-16(15-29(2)3)10-13-30(20)22/h5-10,12-14H,4,11,15H2,1-3H3,(H,25,26,27) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195446
(CHEMBL222158 | N-((2-(4-fluorophenyl)-3-(2-((S)-1-...)Show SMILES CCNCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(n1)[C@@H](C)c1ccccc1 Show InChI InChI=1S/C28H26FN5/c1-3-30-18-20-14-16-34-25(17-20)33-26(22-9-11-23(29)12-10-22)27(34)24-13-15-31-28(32-24)19(2)21-7-5-4-6-8-21/h4-17,19,30H,3,18H2,1-2H3/t19-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211821
(2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethylami...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)C(CO)CO)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C30H31FN6O2/c1-20(22-6-4-3-5-7-22)33-30-32-14-12-26(34-30)29-28(23-8-10-24(31)11-9-23)35-27-16-21(13-15-37(27)29)17-36(2)25(18-38)19-39/h3-16,20,25,38-39H,17-19H2,1-2H3,(H,32,33,34)/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211808
(CHEMBL233008 | N-(2-(((2-(4-fluorophenyl)-3-(2-((S...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CCNS(C)(=O)=O)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C30H32FN7O2S/c1-21(23-7-5-4-6-8-23)34-30-32-15-13-26(35-30)29-28(24-9-11-25(31)12-10-24)36-27-19-22(14-17-38(27)29)20-37(2)18-16-33-41(3,39)40/h4-15,17,19,21,33H,16,18,20H2,1-3H3,(H,32,34,35)/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182361
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C25H29FN6/c1-25(2,3)16-28-24-27-12-10-20(29-24)23-22(18-6-8-19(26)9-7-18)30-21-14-17(15-31(4)5)11-13-32(21)23/h6-14H,15-16H2,1-5H3,(H,27,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182358
(4-(2-(4-fluorophenyl)-7-((methylamino)methyl)H-imi...)Show SMILES CNCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C19H17FN6/c1-22-11-12-7-9-26-16(10-12)25-17(13-2-4-14(20)5-3-13)18(26)15-6-8-23-19(21)24-15/h2-10,22H,11H2,1H3,(H2,21,23,24) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168185
(4-[2-(3-Bromo-4-fluoro-phenyl)-5-(1-methyl-piperid...)Show SMILES CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)c(Br)c1)-c1ccncc1 Show InChI InChI=1S/C21H21BrFN3/c1-26-10-6-15(7-11-26)20-13-17(14-4-8-24-9-5-14)21(25-20)16-2-3-19(23)18(22)12-16/h2-5,8-9,12-13,15,25H,6-7,10-11H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195433
(CHEMBL221689 | N-((2-(4-fluorophenyl)-3-(2-((S)-1-...)Show SMILES C[C@@H](c1ccccc1)c1nccc(n1)-c1c(nc2cc(CNC(C)(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C30H30FN5/c1-20(22-8-6-5-7-9-22)29-32-16-14-25(34-29)28-27(23-10-12-24(31)13-11-23)35-26-18-21(15-17-36(26)28)19-33-30(2,3)4/h5-18,20,33H,19H2,1-4H3/t20-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374591
(CHEMBL255128)Show SMILES O[C@H]1CN[C@H](CN2CCC(CC2)c2cc(c([nH]2)-c2ccc(F)cc2)-c2ccncc2)C1 Show InChI InChI=1S/C25H29FN4O/c26-20-3-1-19(2-4-20)25-23(17-5-9-27-10-6-17)14-24(29-25)18-7-11-30(12-8-18)16-21-13-22(31)15-28-21/h1-6,9-10,14,18,21-22,28-29,31H,7-8,11-13,15-16H2/t21-,22+/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195441
(CHEMBL220598 | N-ethyl-N-((2-(4-fluorophenyl)-3-(2...)Show SMILES CCN(CC)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(n1)[C@@H](C)c1ccccc1 Show InChI InChI=1S/C30H30FN5/c1-4-35(5-2)20-22-16-18-36-27(19-22)34-28(24-11-13-25(31)14-12-24)29(36)26-15-17-32-30(33-26)21(3)23-9-7-6-8-10-23/h6-19,21H,4-5,20H2,1-3H3/t21-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195437
((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethyl)pyrimi...)Show SMILES CNCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(n1)[C@@H](C)c1ccccc1 Show InChI InChI=1S/C27H24FN5/c1-18(20-6-4-3-5-7-20)27-30-14-12-23(31-27)26-25(21-8-10-22(28)11-9-21)32-24-16-19(17-29-2)13-15-33(24)26/h3-16,18,29H,17H2,1-2H3/t18-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50171694
((R)-5-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-py...)Show SMILES O[C@H]1CNC(CN2CCC(CC2)c2cc(c([nH]2)-c2ccc(F)cc2)-c2ccncc2)C1 Show InChI InChI=1S/C25H29FN4O/c26-20-3-1-19(2-4-20)25-23(17-5-9-27-10-6-17)14-24(29-25)18-7-11-30(12-8-18)16-21-13-22(31)15-28-21/h1-6,9-10,14,18,21-22,28-29,31H,7-8,11-13,15-16H2/t21?,22-/m1/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against cGMP-dependent protein kinase from Eimeria tenella |
Bioorg Med Chem Lett 15: 4570-3 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.096
BindingDB Entry DOI: 10.7270/Q2416WM9 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182356
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CNc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN6/c1-23-21-24-10-8-17(25-21)20-19(15-4-6-16(22)7-5-15)26-18-12-14(13-27(2)3)9-11-28(18)20/h4-12H,13H2,1-3H3,(H,23,24,25) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374587
(CHEMBL272573)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CC2CNCCO2)CC1 |w:23.25| Show InChI InChI=1S/C25H29FN4O/c26-21-3-1-20(2-4-21)25-23(18-5-9-27-10-6-18)15-24(29-25)19-7-12-30(13-8-19)17-22-16-28-11-14-31-22/h1-6,9-10,15,19,22,28-29H,7-8,11-14,16-17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182363
(4-(7-(aminomethyl)-2-(4-fluorophenyl)H-imidazo[1,2...)Show SMILES NCc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C18H15FN6/c19-13-3-1-12(2-4-13)16-17(14-5-7-22-18(21)23-14)25-8-6-11(10-20)9-15(25)24-16/h1-9H,10,20H2,(H2,21,22,23) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against PKG |
Bioorg Med Chem Lett 16: 2479-83 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.092
BindingDB Entry DOI: 10.7270/Q24X57CW |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211819
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CC(C)Nc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1 Show InChI InChI=1S/C23H25FN6/c1-15(2)26-23-25-11-9-19(27-23)22-21(17-5-7-18(24)8-6-17)28-20-13-16(14-29(3)4)10-12-30(20)22/h5-13,15H,14H2,1-4H3,(H,25,26,27) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168208
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES NC1(CN2CCC(CC2)c2cc(c([nH]2)-c2ccc(F)cc2)-c2ccncc2)CC1 Show InChI InChI=1S/C24H27FN4/c25-20-3-1-19(2-4-20)23-21(17-5-11-27-12-6-17)15-22(28-23)18-7-13-29(14-8-18)16-24(26)9-10-24/h1-6,11-12,15,18,28H,7-10,13-14,16,26H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211816
((S)-2-(((2-(4-fluorophenyl)-3-(2-((S)-1-phenylethy...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)[C@@H](C)C(=O)N(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C32H34FN7O/c1-21(24-9-7-6-8-10-24)35-32-34-17-15-27(36-32)30-29(25-11-13-26(33)14-12-25)37-28-19-23(16-18-40(28)30)20-39(5)22(2)31(41)38(3)4/h6-19,21-22H,20H2,1-5H3,(H,34,35,36)/t21-,22-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374588
(CHEMBL255381)Show SMILES Fc1ccc(cc1)-c1[nH]c(cc1-c1ccncc1)C1CCN(CC1)C(=O)C1CNCCO1 |w:26.29| Show InChI InChI=1S/C25H27FN4O2/c26-20-3-1-19(2-4-20)24-21(17-5-9-27-10-6-17)15-22(29-24)18-7-12-30(13-8-18)25(31)23-16-28-11-14-32-23/h1-6,9-10,15,18,23,28-29H,7-8,11-14,16H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211810
(4-(2-(4-fluorophenyl)-7-((methyl((tetrahydrofuran-...)Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)CC3CCCO3)ccn12)-c1ccc(F)cc1)c1ccccc1 |w:19.19| Show InChI InChI=1S/C32H33FN6O/c1-22(24-7-4-3-5-8-24)35-32-34-16-14-28(36-32)31-30(25-10-12-26(33)13-11-25)37-29-19-23(15-17-39(29)31)20-38(2)21-27-9-6-18-40-27/h3-5,7-8,10-17,19,22,27H,6,9,18,20-21H2,1-2H3,(H,34,35,36)/t22-,27?/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195443
((3-(2-(benzyloxy)pyrimidin-4-yl)-2-(4-fluorophenyl...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(OCc2ccccc2)n1 Show InChI InChI=1S/C27H24FN5O/c1-32(2)17-20-13-15-33-24(16-20)31-25(21-8-10-22(28)11-9-21)26(33)23-12-14-29-27(30-23)34-18-19-6-4-3-5-7-19/h3-16H,17-18H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50182361
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C25H29FN6/c1-25(2,3)16-28-24-27-12-10-20(29-24)23-22(18-6-8-19(26)9-7-18)30-21-14-17(15-31(4)5)11-13-32(21)23/h6-14H,15-16H2,1-5H3,(H,27,28,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168206
(4-[5-(1-Ethyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-...)Show SMILES CCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C22H24FN3/c1-2-26-13-9-17(10-14-26)21-15-20(16-7-11-24-12-8-16)22(25-21)18-3-5-19(23)6-4-18/h3-8,11-12,15,17,25H,2,9-10,13-14H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168202
(2-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES NCCN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C22H25FN4/c23-19-3-1-18(2-4-19)22-20(16-5-10-25-11-6-16)15-21(26-22)17-7-12-27(13-8-17)14-9-24/h1-6,10-11,15,17,26H,7-9,12-14,24H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168187
(4-{2-(4-Fluoro-phenyl)-5-[1-(1-methyl-azetidin-2-y...)Show SMILES CN1CCC1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H29FN4/c1-29-13-10-22(29)17-30-14-8-19(9-15-30)24-16-23(18-6-11-27-12-7-18)25(28-24)20-2-4-21(26)5-3-20/h2-7,11-12,16,19,22,28H,8-10,13-15,17H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374592
(CHEMBL271922)Show SMILES CN1CC[C@H]1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C25H29FN4/c1-29-13-10-22(29)17-30-14-8-19(9-15-30)24-16-23(18-6-11-27-12-7-18)25(28-24)20-2-4-21(26)5-3-20/h2-7,11-12,16,19,22,28H,8-10,13-15,17H2,1H3/t22-/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211823
(4-(7-((ethyl(methyl)amino)methyl)-2-(4-fluoropheny...)Show SMILES CCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCC(C)(C)C)n1 Show InChI InChI=1S/C26H31FN6/c1-6-32(5)16-18-12-14-33-22(15-18)31-23(19-7-9-20(27)10-8-19)24(33)21-11-13-28-25(30-21)29-17-26(2,3)4/h7-15H,6,16-17H2,1-5H3,(H,28,29,30) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50211818
(CHEMBL233011 | N-tert-butyl-4-(7-((dimethylamino)m...)Show SMILES CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NC(C)(C)C)n1 Show InChI InChI=1S/C24H27FN6/c1-24(2,3)29-23-26-12-10-19(27-23)22-21(17-6-8-18(25)9-7-17)28-20-14-16(15-30(4)5)11-13-31(20)22/h6-14H,15H2,1-5H3,(H,26,27,29) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Et-PKG |
Bioorg Med Chem Lett 17: 3558-61 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.041
BindingDB Entry DOI: 10.7270/Q20P0ZQH |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50195434
(4-(7-((dimethylamino)methyl)-2-(4-fluorophenyl)H-i...)Show SMILES C[C@@H](Nc1nccc(n1)-c1c(nc2cc(CN(C)C)ccn12)-c1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C28H27FN6/c1-19(21-7-5-4-6-8-21)31-28-30-15-13-24(32-28)27-26(22-9-11-23(29)12-10-22)33-25-17-20(18-34(2)3)14-16-35(25)27/h4-17,19H,18H2,1-3H3,(H,30,31,32)/t19-/m1/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 5978-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.127
BindingDB Entry DOI: 10.7270/Q2KS6R6W |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50168192
(1-{4-[5-(4-Fluoro-phenyl)-4-pyridin-4-yl-1H-pyrrol...)Show SMILES CC(=O)CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C23H24FN3O/c1-16(28)15-27-12-8-18(9-13-27)22-14-21(17-6-10-25-11-7-17)23(26-22)19-2-4-20(24)5-3-19/h2-7,10-11,14,18,26H,8-9,12-13,15H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 15: 3296-301 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.060
BindingDB Entry DOI: 10.7270/Q24M9421 |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50374580
(CHEMBL271638)Show SMILES CN1C[C@H](O)C[C@H]1CN1CCC(CC1)c1cc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C26H31FN4O/c1-30-17-23(32)14-22(30)16-31-12-8-19(9-13-31)25-15-24(18-6-10-28-11-7-18)26(29-25)20-2-4-21(27)5-3-20/h2-7,10-11,15,19,22-23,29,32H,8-9,12-14,16-17H2,1H3/t22-,23+/m0/s1 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella cGMP-dependent protein kinase |
Bioorg Med Chem Lett 18: 2019-22 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.104
BindingDB Entry DOI: 10.7270/Q2BV7HHX |
More data for this
Ligand-Target Pair | |
cGMP-dependent protein kinase
(Eimeria tenella) | BDBM50183915
((5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrrol-2-y...)Show InChI InChI=1S/C18H18FN3/c1-22(2)12-16-11-17(13-7-9-20-10-8-13)18(21-16)14-3-5-15(19)6-4-14/h3-11,21H,12H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.350 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of Eimeria tenella PKG |
Bioorg Med Chem Lett 16: 2817-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.01.041
BindingDB Entry DOI: 10.7270/Q21V5DK1 |
More data for this
Ligand-Target Pair | |
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