| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor gamma |
|---|
| Ligand | BDBM50195707 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_425030 (CHEMBL912551) |
|---|
| IC50 | 72±n/a nM |
|---|
| Citation |  Warshawsky, AM; Alt, CA; Brozinick, JT; Harkness, AR; Hawkins, ED; Henry, JR; Matthews, DP; Miller, AR; Misener, EA; Montrose-Rafizadeh, C; Rhodes, GA; Shen, Q; Vance, JA; Udodong, UE; Wang, M; Zhang, TY; Zink, RW Synthesis and evaluation of aminomethyl dihydrocinnamates as a new class of PPAR ligands. Bioorg Med Chem Lett16:6328-33 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Peroxisome proliferator-activated receptor gamma |
|---|
| Name: | Peroxisome proliferator-activated receptor gamma |
|---|
| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 |
|---|
| Type: | Nuclear Receptor |
|---|
| Mol. Mass.: | 57613.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P37231 |
|---|
| Residue: | 505 |
|---|
| Sequence: | MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSF
DIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKT
QLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNC
RIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLR
ALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQE
QSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLAS
LMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVII
LSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQL
LQVIKKTETDMSLHPLLQEIYKDLY
|
|
|
|---|
| BDBM50195707 |
|---|
| n/a |
|---|
| Name | BDBM50195707 |
|---|
| Synonyms: | 3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-2-((phenylmethylsulfonamido)methyl)phenyl)propanoic acid | CHEMBL219773 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H30N2O6S |
|---|
| Mol. Mass. | 534.623 |
|---|
| SMILES | Cc1oc(nc1CCOc1ccc(CCC(O)=O)c(CNS(=O)(=O)Cc2ccccc2)c1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
