| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 3 |
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| Ligand | BDBM50612011 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2285465 |
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| IC50 | 23±n/a nM |
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| Citation |  Tao, Y; Hao, X; Ding, X; Cherukupalli, S; Song, Y; Liu, X; Zhan, P Medicinal chemistry insights into novel CDC25 inhibitors. Eur J Med Chem201:0 (2020) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 3 |
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| Name: | M-phase inducer phosphatase 3 |
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| Synonyms: | CDC25C | Dual specificity phosphatase Cdc25C | M-phase inducer phosphatase 3 | MPIP3_HUMAN |
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| Type: | Substrate |
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| Mol. Mass.: | 53366.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30307 |
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| Residue: | 473 |
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| Sequence: | MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK
CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP
NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK
VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ
DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK
PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF
PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
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| BDBM50612011 |
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| n/a |
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| Name | BDBM50612011 |
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| Synonyms: | CHEMBL5288122 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N3O2S |
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| Mol. Mass. | 265.331 |
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| SMILES | CN(C)CCNC1=CC(=O)c2sc(C)nc2C1=O |t:6| |
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| Structure | 
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