| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50199862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_441143 (CHEMBL891362) |
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| Ki | 51.5±n/a nM |
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| Citation |  Li, T; Jinsmaa, Y; Nedachi, M; Miyazaki, A; Tsuda, Y; Ambo, A; Sasaki, Y; Bryant, SD; Marczak, E; Li, Q; Swartzwelder, HS; Lazarus, LH; Okada, Y Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists. Bioorg Med Chem15:1237-51 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40465.04 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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| BDBM50199862 |
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| n/a |
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| Name | BDBM50199862 |
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| Synonyms: | (S)-2-allylamino-N-{6-[(S)-2-allylamino-3-(4-hydroxy-phenyl)-propionylamino]-hexyl}-3-(4-hydroxy-phenyl)-propionamide | CHEMBL232303 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H42N4O4 |
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| Mol. Mass. | 522.6789 |
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| SMILES | Oc1ccc(C[C@H](NCC=C)C(=O)NCCCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NCC=C)cc1 |
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| Structure | 
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