| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor A |
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| Ligand | BDBM50221323 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_457557 (CHEMBL922757) |
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| Ki | >10000±n/a nM |
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| Citation |  Murugaiah, AM; Wallinder, C; Mahalingam, AK; Wu, X; Wan, Y; Plouffe, B; Botros, M; Karlén, A; Hallberg, M; Gallo-Payet, N; Alterman, M Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system. Bioorg Med Chem15:7166-83 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor A |
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| Name: | Type-1 angiotensin II receptor A |
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| Synonyms: | AGTRA_RAT | ANGIOTENSIN AT1 | Agtr1 | Agtr1a | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | At1a | Type-1A angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40910.53 |
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| Organism: | RAT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RAT::P25095 |
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| Residue: | 359 |
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| Sequence: | MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
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| BDBM50221323 |
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| n/a |
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| Name | BDBM50221323 |
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| Synonyms: | CHEMBL246461 | N-butyloxycarbonyl-3-[4-(dimethylaminomethyl)phenyl]-5-iso-butylthiophene-2-sulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H32N2O4S2 |
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| Mol. Mass. | 452.63 |
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| SMILES | CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(C)C)cc1 |
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| Structure | 
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