Compile Data Set for Download or QSAR

Found 267 hits with Last Name = 'botros' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor B (RAT)	BDBM50370684 (CHEMBL1791349) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C49H71N13O10/c1-6-29(4)41(46(69)58-36(24-32-25-53-27-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)40(28(2)3)60-42(65)34(56-39(64)26-52-5)14-10-20-54-49(50)51/h7-9,12-13,16-19,25,27-29,34-38,40-41,52,63H,6,10-11,14-15,20-24,26H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,50,51,54)/t29-,34+,35+,36+,37+,38+,40+,41+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for angiotensin II receptor, type 1 in rat liver membrane using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 2 hr at ...				J Med Chem 48: 6620-31 (2005) Article DOI: 10.1021/jm050280z BindingDB Entry DOI: 10.7270/Q2HX1DG6
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370684 (CHEMBL1791349) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C49H71N13O10/c1-6-29(4)41(46(69)58-36(24-32-25-53-27-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)40(28(2)3)60-42(65)34(56-39(64)26-52-5)14-10-20-54-49(50)51/h7-9,12-13,16-19,25,27-29,34-38,40-41,52,63H,6,10-11,14-15,20-24,26H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,50,51,54)/t29-,34+,35+,36+,37+,38+,40+,41+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 h...				J Med Chem 48: 6620-31 (2005) Article DOI: 10.1021/jm050280z BindingDB Entry DOI: 10.7270/Q2HX1DG6
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370575 (CHEMBL1791308) Show SMILES CC[C@@H](C)[C@H](N1Cc2cccc(NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)c2N[C@@H](Cc2ccc(O)cc2)C1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |wU:68.73,15.15,55.57,41.42,30.30,2.2,wD:4.4,19.26,72.76,(20.86,-11.16,;20.86,-9.62,;19.5,-8.85,;18.13,-9.62,;19.5,-7.31,;18.13,-6.53,;17.29,-7.83,;15.7,-8,;15.29,-9.47,;13.78,-9.86,;12.67,-8.77,;13.1,-7.3,;11.74,-6.61,;10.41,-7.27,;10.41,-8.62,;9.06,-6.59,;7.72,-7.27,;6.37,-6.59,;6.4,-5.24,;5.03,-7.24,;5.03,-8.61,;6.22,-9.28,;6.2,-10.63,;7.41,-11.31,;7.4,-12.65,;6.2,-13.32,;8.58,-13.35,;3.69,-6.58,;2.35,-7.24,;2.35,-8.58,;.99,-6.58,;-.35,-7.21,;1.02,-5.24,;-.33,-4.54,;-1.69,-5.21,;-.32,-3.2,;9.07,-5.22,;10.45,-4.54,;7.71,-4.51,;14.61,-6.9,;14.8,-5.36,;16.14,-4.57,;15.99,-3.04,;16.77,-1.69,;15.97,-.38,;16.74,.97,;18.32,.97,;19.09,2.32,;19.13,-.34,;18.35,-1.69,;17.63,-5.09,;18.76,-3.99,;20.86,-6.53,;20.86,-5,;22.25,-7.3,;23.67,-6.69,;23.73,-5.14,;24.52,-3.79,;26.07,-3.63,;26.4,-2.11,;25.03,-1.35,;23.84,-2.38,;25,-7.41,;24.92,-8.77,;26.39,-6.67,;25.88,-5.19,;27.18,-4.28,;28.45,-5.19,;27.97,-6.67,;29.35,-7.43,;29.34,-8.98,;30.71,-6.67,;32.02,-7.41,;31.94,-8.77,;33.27,-9.48,;34.67,-8.88,;35.98,-9.63,;35.9,-10.95,;34.48,-11.61,;33.19,-10.87,;33.44,-6.8,;34.77,-7.53,;33.52,-5.43,)| Show InChI InChI=1S/C57H76N14O12/c1-5-32(4)48(53(79)67-42(26-36-28-61-30-63-36)54(80)70-23-11-17-44(70)51(77)68-43(56(82)83)25-33-12-7-6-8-13-33)71-29-35-14-9-15-39(47(35)64-41(55(71)81)24-34-18-20-37(72)21-19-34)65-52(78)46(31(2)3)69-50(76)40(16-10-22-62-57(59)60)66-49(75)38(58)27-45(73)74/h6-9,12-15,18-21,28,30-32,38,40-44,46,48,64,72H,5,10-11,16-17,22-27,29,58H2,1-4H3,(H,61,63)(H,65,78)(H,66,75)(H,67,79)(H,68,77)(H,69,76)(H,73,74)(H,82,83)(H4,59,60,62)/t32-,38+,40+,41+,42+,43+,44+,46+,48+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370575 (CHEMBL1791308) Show SMILES CC[C@@H](C)[C@H](N1Cc2cccc(NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)c2N[C@@H](Cc2ccc(O)cc2)C1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |wU:68.73,15.15,55.57,41.42,30.30,2.2,wD:4.4,19.26,72.76,(20.86,-11.16,;20.86,-9.62,;19.5,-8.85,;18.13,-9.62,;19.5,-7.31,;18.13,-6.53,;17.29,-7.83,;15.7,-8,;15.29,-9.47,;13.78,-9.86,;12.67,-8.77,;13.1,-7.3,;11.74,-6.61,;10.41,-7.27,;10.41,-8.62,;9.06,-6.59,;7.72,-7.27,;6.37,-6.59,;6.4,-5.24,;5.03,-7.24,;5.03,-8.61,;6.22,-9.28,;6.2,-10.63,;7.41,-11.31,;7.4,-12.65,;6.2,-13.32,;8.58,-13.35,;3.69,-6.58,;2.35,-7.24,;2.35,-8.58,;.99,-6.58,;-.35,-7.21,;1.02,-5.24,;-.33,-4.54,;-1.69,-5.21,;-.32,-3.2,;9.07,-5.22,;10.45,-4.54,;7.71,-4.51,;14.61,-6.9,;14.8,-5.36,;16.14,-4.57,;15.99,-3.04,;16.77,-1.69,;15.97,-.38,;16.74,.97,;18.32,.97,;19.09,2.32,;19.13,-.34,;18.35,-1.69,;17.63,-5.09,;18.76,-3.99,;20.86,-6.53,;20.86,-5,;22.25,-7.3,;23.67,-6.69,;23.73,-5.14,;24.52,-3.79,;26.07,-3.63,;26.4,-2.11,;25.03,-1.35,;23.84,-2.38,;25,-7.41,;24.92,-8.77,;26.39,-6.67,;25.88,-5.19,;27.18,-4.28,;28.45,-5.19,;27.97,-6.67,;29.35,-7.43,;29.34,-8.98,;30.71,-6.67,;32.02,-7.41,;31.94,-8.77,;33.27,-9.48,;34.67,-8.88,;35.98,-9.63,;35.9,-10.95,;34.48,-11.61,;33.19,-10.87,;33.44,-6.8,;34.77,-7.53,;33.52,-5.43,)| Show InChI InChI=1S/C57H76N14O12/c1-5-32(4)48(53(79)67-42(26-36-28-61-30-63-36)54(80)70-23-11-17-44(70)51(77)68-43(56(82)83)25-33-12-7-6-8-13-33)71-29-35-14-9-15-39(47(35)64-41(55(71)81)24-34-18-20-37(72)21-19-34)65-52(78)46(31(2)3)69-50(76)40(16-10-22-62-57(59)60)66-49(75)38(58)27-45(73)74/h6-9,12-15,18-21,28,30-32,38,40-44,46,48,64,72H,5,10-11,16-17,22-27,29,58H2,1-4H3,(H,61,63)(H,65,78)(H,66,75)(H,67,79)(H,68,77)(H,69,76)(H,73,74)(H,82,83)(H4,59,60,62)/t32-,38+,40+,41+,42+,43+,44+,46+,48+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity to AT2 receptor				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199311 (CHEMBL215160 | N-butyloxycarbonyl-2-(4-imidazol-1-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(OCCCC)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C25H31N3O5S/c1-3-5-15-32-22-11-12-24(34(30,31)27-25(29)33-16-6-4-2)23(17-22)21-9-7-20(8-10-21)18-28-14-13-26-19-28/h7-14,17,19H,3-6,15-16,18H2,1-2H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C25H31N3O4S/c1-4-5-14-32-25(29)27-33(30,31)24-11-8-21(15-19(2)3)16-23(24)22-9-6-20(7-10-22)17-28-13-12-26-18-28/h6-13,16,18-19H,4-5,14-15,17H2,1-3H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50139783 (Angiotensin II analogue | CHEMBL404996) Show SMILES CCSC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C47H65N13O12S2/c1-2-74-24-36(43(68)56-33(20-28-22-51-25-53-28)45(70)60-17-7-11-37(60)44(69)57-34(46(71)72)19-26-8-4-3-5-9-26)59-41(66)32(18-27-12-14-29(61)15-13-27)55-42(67)35(23-73)58-40(65)31(10-6-16-52-47(49)50)54-39(64)30(48)21-38(62)63/h3-5,8-9,12-15,22,25,30-37,61,73H,2,6-7,10-11,16-21,23-24,48H2,1H3,(H,51,53)(H,54,64)(H,55,67)(H,56,68)(H,57,69)(H,58,65)(H,59,66)(H,62,63)(H,71,72)(H4,49,50,52)/t30-,31-,32-,33-,34-,35-,36-,37-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometrium				J Med Chem 47: 859-70 (2004) Article DOI: 10.1021/jm030921v BindingDB Entry DOI: 10.7270/Q2736RNQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50141059 (CHEMBL289614 | L-162782 | N-Butyloxycarbonyl-4'-(2...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C32H40N4O4S/c1-7-9-16-40-32(37)35-41(38,39)28-15-12-25(17-21(3)4)19-27(28)26-13-10-24(11-14-26)20-36-29(8-2)34-30-22(5)18-23(6)33-31(30)36/h10-15,18-19,21H,7-9,16-17,20H2,1-6H3,(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370375 (CHEMBL268815) Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#7])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C53H74N12O12/c1-5-30(4)44(50(74)61-39(26-32-15-19-34(54)20-16-32)51(75)65-24-10-14-41(65)48(72)62-40(52(76)77)27-31-11-7-6-8-12-31)64-47(71)38(25-33-17-21-35(66)22-18-33)60-49(73)43(29(2)3)63-46(70)37(13-9-23-58-53(56)57)59-45(69)36(55)28-42(67)68/h6-8,11-12,15-22,29-30,36-41,43-44,66H,5,9-10,13-14,23-28,54-55H2,1-4H3,(H,59,69)(H,60,73)(H,61,74)(H,62,72)(H,63,70)(H,64,71)(H,67,68)(H,76,77)(H4,56,57,58)/t30-,36+,37+,38+,39+,40+,41+,43+,44+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometrium				J Med Chem 49: 6133-7 (2006) Article DOI: 10.1021/jm051222g BindingDB Entry DOI: 10.7270/Q28P619Q
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50199326 (CHEMBL217673 | N-butyloxycarbonyl-2-(4-imidazol-1-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C25H31N3O4S/c1-4-5-14-32-25(29)27-33(30,31)24-11-8-21(15-19(2)3)16-23(24)22-9-6-20(7-10-22)17-28-13-12-26-18-28/h6-13,16,18-19H,4-5,14-15,17H2,1-3H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370686 (CHEMBL1791350) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](N)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C46H68N12O11/c1-5-26(4)36(56-43(66)37(48)57-41(64)35(25(2)3)55-39(62)30(18-12-20-51-46(49)50)52-38(61)29(47)24-34(59)60)42(65)53-31(22-27-14-8-6-9-15-27)44(67)58-21-13-19-33(58)40(63)54-32(45(68)69)23-28-16-10-7-11-17-28/h6-11,14-17,25-26,29-33,35-37H,5,12-13,18-24,47-48H2,1-4H3,(H,52,61)(H,53,65)(H,54,63)(H,55,62)(H,56,66)(H,57,64)(H,59,60)(H,68,69)(H4,49,50,51)/t26-,29+,30+,31+,32+,33+,35+,36+,37-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 h...				J Med Chem 48: 6620-31 (2005) Article DOI: 10.1021/jm050280z BindingDB Entry DOI: 10.7270/Q2HX1DG6
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50168428 ((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-4-({[(2S)-...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(=O)Nc1cccc2CN(CC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc3ccccc3)C(O)=O)C(=O)[C@H](Cc3ccc(O)cc3)Nc12 Show InChI InChI=1S/C53H68N14O12/c1-29(2)44(65-47(73)37(13-7-19-58-53(55)56)63-46(72)35(54)24-43(70)71)49(75)62-36-12-6-11-32-26-66(50(76)38(61-45(32)36)21-31-15-17-34(68)18-16-31)27-42(69)60-39(23-33-25-57-28-59-33)51(77)67-20-8-14-41(67)48(74)64-40(52(78)79)22-30-9-4-3-5-10-30/h3-6,9-12,15-18,25,28-29,35,37-41,44,61,68H,7-8,13-14,19-24,26-27,54H2,1-2H3,(H,57,59)(H,60,69)(H,62,75)(H,63,72)(H,64,74)(H,65,73)(H,70,71)(H,78,79)(H4,55,56,58)/t35-,37-,38-,39-,40-,41-,44-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370375 (CHEMBL268815) Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#7])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C53H74N12O12/c1-5-30(4)44(50(74)61-39(26-32-15-19-34(54)20-16-32)51(75)65-24-10-14-41(65)48(72)62-40(52(76)77)27-31-11-7-6-8-12-31)64-47(71)38(25-33-17-21-35(66)22-18-33)60-49(73)43(29(2)3)63-46(70)37(13-9-23-58-53(56)57)59-45(69)36(55)28-42(67)68/h6-8,11-12,15-22,29-30,36-41,43-44,66H,5,9-10,13-14,23-28,54-55H2,1-4H3,(H,59,69)(H,60,73)(H,61,74)(H,62,72)(H,63,70)(H,64,71)(H,67,68)(H,76,77)(H4,56,57,58)/t30-,36+,37+,38+,39+,40+,41+,43+,44+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50208102 (CHEMBL424755 | [4-NH2-Phe6] Ang II) Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(N)cc1)C(O)=O |wU:8.17,24.32,60.63,47.47,2.2,wD:4.4,20.21,64.66,35.36,(17.7,-20.36,;17.7,-18.82,;16.36,-18.05,;15.03,-18.83,;16.36,-16.51,;15.03,-15.75,;13.7,-16.52,;13.7,-18.06,;12.37,-15.76,;12.36,-14.22,;13.7,-13.44,;15.03,-14.21,;16.36,-13.44,;16.35,-11.9,;17.69,-11.13,;15.01,-11.13,;13.68,-11.91,;11.04,-16.53,;9.71,-15.77,;9.7,-14.23,;8.38,-16.54,;7.05,-15.77,;5.72,-16.54,;5.72,-18.08,;4.39,-15.78,;4.38,-14.24,;3.05,-13.47,;3.04,-11.93,;1.71,-11.17,;1.71,-9.63,;.37,-8.86,;3.04,-8.85,;3.06,-16.55,;1.73,-15.79,;1.72,-14.25,;.4,-16.56,;-.94,-15.79,;.4,-18.1,;-.93,-18.87,;-.93,-20.41,;-2.27,-18.1,;8.38,-18.08,;7.05,-18.85,;9.72,-18.84,;17.69,-15.74,;17.68,-14.2,;19.02,-16.5,;20.35,-15.73,;20.34,-14.19,;21.39,-13.06,;21.08,-11.55,;22.42,-10.8,;23.55,-11.84,;22.91,-13.24,;21.68,-16.5,;21.68,-18.04,;23.01,-15.72,;23.17,-14.19,;24.67,-13.86,;25.44,-15.19,;24.42,-16.34,;24.88,-17.81,;23.84,-18.94,;26.38,-18.15,;26.84,-19.62,;25.51,-20.4,;25.53,-21.94,;24.2,-22.71,;24.22,-24.25,;25.56,-25.01,;25.57,-26.55,;26.89,-24.22,;26.87,-22.68,;28.34,-19.95,;28.81,-21.42,;29.39,-18.82,)| Show InChI InChI=1S/C50H72N14O12/c1-5-27(4)41(47(73)60-36(22-31-24-55-25-57-31)48(74)64-19-7-9-38(64)45(71)61-37(49(75)76)21-28-10-14-30(51)15-11-28)63-44(70)35(20-29-12-16-32(65)17-13-29)59-46(72)40(26(2)3)62-43(69)34(8-6-18-56-50(53)54)58-42(68)33(52)23-39(66)67/h10-17,24-27,33-38,40-41,65H,5-9,18-23,51-52H2,1-4H3,(H,55,57)(H,58,68)(H,59,72)(H,60,73)(H,61,71)(H,62,69)(H,63,70)(H,66,67)(H,75,76)(H4,53,54,56)/t27-,33+,34+,35+,36+,37+,38+,40+,41+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometrial membrane				J Med Chem 50: 1711-5 (2007) Article DOI: 10.1021/jm0613469 BindingDB Entry DOI: 10.7270/Q2NK3FTN
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50251514 (CHEMBL480906 | N-Butoxycarbonyl-3-[4-(N-benzylcarb...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C27H32N2O5S2/c1-4-5-15-34-27(31)29-36(32,33)26-24(17-23(35-26)16-19(2)3)21-11-13-22(14-12-21)25(30)28-18-20-9-7-6-8-10-20/h6-14,17,19H,4-5,15-16,18H2,1-3H3,(H,28,30)(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199331 (CHEMBL216250 | N-(1-butyloxy-methylcarbonyl)-3-(4-...) Show SMILES CCCCOCC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C24H31N3O4S2/c1-4-5-12-31-16-23(28)26-33(29,30)24-22(14-21(32-24)13-18(2)3)20-8-6-19(7-9-20)15-27-11-10-25-17-27/h6-11,14,17-18H,4-5,12-13,15-16H2,1-3H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (RAT)	BDBM50049189 (3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT1 receptor in rat liver membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Substance-P receptor (Rattus norvegicus (rat))	BDBM50188489 ((S)-2-Amino-N-((S)-1-carbamoyl-2-phenyl-ethyl)-3-p...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O Show InChI InChI=1S/C18H21N3O2/c19-15(11-13-7-3-1-4-8-13)18(23)21-16(17(20)22)12-14-9-5-2-6-10-14/h1-10,15-16H,11-12,19H2,(H2,20,22)(H,21,23)/t15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membrane				J Med Chem 53: 2383-9 (2010) Article DOI: 10.1021/jm901352b BindingDB Entry DOI: 10.7270/Q2542NQK
					More data for this Ligand-Target Pair
Substance-P receptor (Rattus norvegicus (rat))	BDBM50308381 (CHEMBL589979 | H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-OH) Show SMILES [#7]-[#6]-[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |r| Show InChI InChI=1S/C41H65N13O10/c42-19-5-4-12-28(51-37(60)30-13-7-21-53(30)38(61)25(43)11-6-20-48-41(46)47)39(62)54-22-8-14-31(54)36(59)50-27(16-18-33(45)56)34(57)49-26(15-17-32(44)55)35(58)52-29(40(63)64)23-24-9-2-1-3-10-24/h1-3,9-10,25-31H,4-8,11-23,42-43H2,(H2,44,55)(H2,45,56)(H,49,57)(H,50,59)(H,51,60)(H,52,58)(H,63,64)(H4,46,47,48)/t25-,26-,27-,28-,29-,30-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membrane				J Med Chem 53: 2383-9 (2010) Article DOI: 10.1021/jm901352b BindingDB Entry DOI: 10.7270/Q2542NQK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50195697 ((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-2-[(2S)-bu...) Show SMILES CC[C@H](C)[C@@H]1Nc2c(Cc3ccc(O)cc3)cc(NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)cc2CN(CC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2ccccc2)C(O)=O)C1=O |wU:25.33,70.73,4.3,2.2,wD:53.54,36.37,21.22,66.70,(14.02,-9.64,;14.01,-11.18,;12.68,-11.94,;11.35,-11.17,;12.67,-13.48,;11.16,-13.15,;9.94,-14.11,;8.6,-13.34,;8.6,-11.8,;7.26,-11.03,;7.27,-9.49,;5.93,-8.73,;4.6,-9.5,;3.26,-8.73,;4.61,-11.05,;5.95,-11.81,;7.28,-14.11,;7.28,-15.65,;5.96,-16.41,;4.62,-15.64,;4.62,-14.1,;3.28,-16.41,;1.95,-15.64,;.62,-16.41,;.62,-17.95,;-.72,-15.64,;-.72,-14.1,;-2.05,-13.33,;-2.05,-11.79,;-3.38,-11.02,;-3.38,-9.48,;-4.71,-8.71,;-2.05,-8.71,;-2.05,-16.41,;-3.38,-15.64,;-3.38,-14.1,;-4.71,-16.41,;-6.05,-15.64,;-4.71,-17.95,;-6.05,-18.72,;-7.39,-17.95,;-6.05,-20.26,;3.28,-17.95,;1.95,-18.72,;4.62,-18.72,;8.61,-16.42,;9.94,-15.65,;11.15,-16.63,;12.67,-16.28,;13.62,-17.48,;15.16,-17.51,;15.91,-18.86,;15.96,-16.19,;17.5,-16.21,;18.65,-17.24,;18.55,-18.78,;19.77,-19.74,;19.16,-21.18,;17.62,-21.06,;17.26,-19.56,;18.25,-14.87,;17.46,-13.55,;19.79,-14.86,;20.14,-16.33,;21.66,-16.52,;22.26,-15.08,;21.07,-14.07,;21.07,-12.53,;19.73,-11.76,;22.4,-11.75,;22.43,-10.22,;21.11,-9.42,;21.13,-7.87,;22.48,-7.13,;22.51,-5.6,;21.19,-4.8,;19.85,-5.53,;19.81,-7.08,;23.77,-9.47,;23.8,-7.93,;25.09,-10.26,;13.34,-14.88,;14.88,-14.88,)| Show InChI InChI=1S/C57H76N14O12/c1-5-32(4)48-55(81)70(29-45(73)65-42(25-38-27-61-30-63-38)54(80)71-20-10-14-44(71)52(78)67-43(56(82)83)22-33-11-7-6-8-12-33)28-36-24-37(23-35(49(36)68-48)21-34-15-17-39(72)18-16-34)64-53(79)47(31(2)3)69-51(77)41(13-9-19-62-57(59)60)66-50(76)40(58)26-46(74)75/h6-8,11-12,15-18,23-24,27,30-32,40-44,47-48,68,72H,5,9-10,13-14,19-22,25-26,28-29,58H2,1-4H3,(H,61,63)(H,64,79)(H,65,73)(H,66,76)(H,67,78)(H,69,77)(H,74,75)(H,82,83)(H4,59,60,62)/t32-,40-,41-,42-,43-,44-,47-,48-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometrium				J Med Chem 49: 6133-7 (2006) Article DOI: 10.1021/jm051222g BindingDB Entry DOI: 10.7270/Q28P619Q
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50175584 ((S)-3-Amino-N-((S)-1-{1-[(S)-3-[2-[2-((S)-(S)-1-ca...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(=O)NCc1cc(Cc2ccc(O)cc2)cc(c1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C50H64N12O11/c1-28(2)42(61-45(68)37(10-6-16-55-50(52)53)58-44(67)36(51)24-41(64)65)47(70)56-25-32-19-31(18-30-12-14-35(63)15-13-30)20-33(21-32)43(66)59-38(23-34-26-54-27-57-34)48(71)62-17-7-11-40(62)46(69)60-39(49(72)73)22-29-8-4-3-5-9-29/h3-5,8-9,12-15,19-21,26-28,36-40,42,63H,6-7,10-11,16-18,22-25,51H2,1-2H3,(H,54,57)(H,56,70)(H,58,67)(H,59,66)(H,60,69)(H,61,68)(H,64,65)(H,72,73)(H4,52,53,55)/t36-,37-,38-,39-,40-,42-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for angiotensin II receptor, type 2 in pig uterus myometrium using [125I]-Ang II as radioligand, in pH 7.4 Tris-HCl buffer for 1.5 h...				J Med Chem 48: 6620-31 (2005) Article DOI: 10.1021/jm050280z BindingDB Entry DOI: 10.7270/Q2HX1DG6
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50049189 (3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199317 (CHEMBL214525 | N-ethyloxycarbonyl-2-(4-imidazol-1-...) Show SMILES CCCCc1ccc(c(c1)-c1ccc(Cn2ccnc2)cc1)S(=O)(=O)NC(=O)OCC Show InChI InChI=1S/C23H27N3O4S/c1-3-5-6-18-9-12-22(31(28,29)25-23(27)30-4-2)21(15-18)20-10-7-19(8-11-20)16-26-14-13-24-17-26/h7-15,17H,3-6,16H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370375 (CHEMBL268815) Show SMILES [#6]-[#6]-[#6@@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6](-[#8])=O)-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#7])cc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C53H74N12O12/c1-5-30(4)44(50(74)61-39(26-32-15-19-34(54)20-16-32)51(75)65-24-10-14-41(65)48(72)62-40(52(76)77)27-31-11-7-6-8-12-31)64-47(71)38(25-33-17-21-35(66)22-18-33)60-49(73)43(29(2)3)63-46(70)37(13-9-23-58-53(56)57)59-45(69)36(55)28-42(67)68/h6-8,11-12,15-22,29-30,36-41,43-44,66H,5,9-10,13-14,23-28,54-55H2,1-4H3,(H,59,69)(H,60,73)(H,61,74)(H,62,72)(H,63,70)(H,64,71)(H,67,68)(H,76,77)(H4,56,57,58)/t30-,36+,37+,38+,39+,40+,41+,43+,44+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometrium				J Med Chem 47: 859-70 (2004) Article DOI: 10.1021/jm030921v BindingDB Entry DOI: 10.7270/Q2736RNQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (RAT)	BDBM50141059 (CHEMBL289614 | L-162782 | N-Butyloxycarbonyl-4'-(2...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C32H40N4O4S/c1-7-9-16-40-32(37)35-41(38,39)28-15-12-25(17-21(3)4)19-27(28)26-13-10-24(11-14-26)20-36-29(8-2)34-30-22(5)18-23(6)33-31(30)36/h10-15,18-19,21H,7-9,16-17,20H2,1-6H3,(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT1 receptor in rat liver membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321070 (CHEMBL1164560 | N-Butyloxycarbonyl-3-(4-pyrazole-1...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2cccn2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-4-5-13-30-23(27)25-32(28,29)22-21(15-20(31-22)14-17(2)3)19-9-7-18(8-10-19)16-26-12-6-11-24-26/h6-12,15,17H,4-5,13-14,16H2,1-3H3,(H,25,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370576 (CHEMBL1791309) Show SMILES CC[C@@H](C)[C@H](N1Cc2cccc(NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)c2N[C@@H](Cc2ccc(O)cc2)C1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |wU:61.66,48.50,15.22,34.35,2.2,wD:4.4,65.69,26.26,(17.04,-11.58,;17.04,-10.04,;15.66,-9.27,;14.31,-10.04,;15.66,-7.73,;14.31,-6.96,;13.45,-8.27,;11.88,-8.43,;11.49,-9.89,;9.96,-10.28,;8.85,-9.2,;9.27,-7.73,;7.91,-6.94,;6.57,-7.6,;6.59,-8.95,;5.22,-6.94,;5.22,-5.59,;3.89,-4.92,;3.91,-3.59,;2.54,-2.91,;2.56,-1.57,;1.23,-.89,;3.92,-.92,;3.91,-7.62,;2.54,-6.94,;2.54,-5.61,;1.2,-7.62,;-.15,-6.96,;1.2,-8.95,;-.12,-9.64,;-1.47,-8.98,;-.11,-10.97,;10.79,-7.33,;10.97,-5.81,;12.32,-5.01,;12.16,-3.47,;12.94,-2.15,;14.52,-2.12,;15.29,-.81,;14.5,.52,;15.27,1.86,;12.91,.49,;12.14,-.84,;13.8,-5.53,;14.93,-4.46,;17.04,-6.96,;17.04,-5.43,;18.42,-7.73,;19.82,-7.11,;19.89,-5.56,;20.67,-4.25,;22.22,-4.06,;22.54,-2.56,;21.18,-1.8,;20.01,-2.83,;21.14,-7.82,;21.05,-9.2,;22.54,-7.1,;22.04,-5.64,;23.33,-4.73,;24.61,-5.64,;24.12,-7.1,;25.48,-7.86,;25.48,-9.4,;26.86,-7.11,;28.17,-7.85,;28.07,-9.22,;29.42,-9.91,;29.32,-11.29,;30.62,-12.02,;32.03,-11.39,;32.13,-10.05,;30.8,-9.29,;29.59,-7.23,;30.9,-7.96,;29.66,-5.86,)| Show InChI InChI=1S/C52H67N13O11/c1-3-29(2)44(48(72)62-39(24-33-26-56-28-58-33)49(73)64-21-9-15-41(64)47(71)63-40(51(75)76)23-30-10-5-4-6-11-30)65-27-32-12-7-13-36(43(32)59-38(50(65)74)22-31-16-18-34(66)19-17-31)60-46(70)37(14-8-20-57-52(54)55)61-45(69)35(53)25-42(67)68/h4-7,10-13,16-19,26,28-29,35,37-41,44,59,66H,3,8-9,14-15,20-25,27,53H2,1-2H3,(H,56,58)(H,60,70)(H,61,69)(H,62,72)(H,63,71)(H,67,68)(H,75,76)(H4,54,55,57)/t29-,35+,37+,38+,39+,40+,41+,44+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50370576 (CHEMBL1791309) Show SMILES CC[C@@H](C)[C@H](N1Cc2cccc(NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)c2N[C@@H](Cc2ccc(O)cc2)C1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |wU:61.66,48.50,15.22,34.35,2.2,wD:4.4,65.69,26.26,(17.04,-11.58,;17.04,-10.04,;15.66,-9.27,;14.31,-10.04,;15.66,-7.73,;14.31,-6.96,;13.45,-8.27,;11.88,-8.43,;11.49,-9.89,;9.96,-10.28,;8.85,-9.2,;9.27,-7.73,;7.91,-6.94,;6.57,-7.6,;6.59,-8.95,;5.22,-6.94,;5.22,-5.59,;3.89,-4.92,;3.91,-3.59,;2.54,-2.91,;2.56,-1.57,;1.23,-.89,;3.92,-.92,;3.91,-7.62,;2.54,-6.94,;2.54,-5.61,;1.2,-7.62,;-.15,-6.96,;1.2,-8.95,;-.12,-9.64,;-1.47,-8.98,;-.11,-10.97,;10.79,-7.33,;10.97,-5.81,;12.32,-5.01,;12.16,-3.47,;12.94,-2.15,;14.52,-2.12,;15.29,-.81,;14.5,.52,;15.27,1.86,;12.91,.49,;12.14,-.84,;13.8,-5.53,;14.93,-4.46,;17.04,-6.96,;17.04,-5.43,;18.42,-7.73,;19.82,-7.11,;19.89,-5.56,;20.67,-4.25,;22.22,-4.06,;22.54,-2.56,;21.18,-1.8,;20.01,-2.83,;21.14,-7.82,;21.05,-9.2,;22.54,-7.1,;22.04,-5.64,;23.33,-4.73,;24.61,-5.64,;24.12,-7.1,;25.48,-7.86,;25.48,-9.4,;26.86,-7.11,;28.17,-7.85,;28.07,-9.22,;29.42,-9.91,;29.32,-11.29,;30.62,-12.02,;32.03,-11.39,;32.13,-10.05,;30.8,-9.29,;29.59,-7.23,;30.9,-7.96,;29.66,-5.86,)| Show InChI InChI=1S/C52H67N13O11/c1-3-29(2)44(48(72)62-39(24-33-26-56-28-58-33)49(73)64-21-9-15-41(64)47(71)63-40(51(75)76)23-30-10-5-4-6-11-30)65-27-32-12-7-13-36(43(32)59-38(50(65)74)22-31-16-18-34(66)19-17-31)60-46(70)37(14-8-20-57-52(54)55)61-45(69)35(53)25-42(67)68/h4-7,10-13,16-19,26,28-29,35,37-41,44,59,66H,3,8-9,14-15,20-25,27,53H2,1-2H3,(H,56,58)(H,60,70)(H,61,69)(H,62,72)(H,63,71)(H,67,68)(H,75,76)(H4,54,55,57)/t29-,35+,37+,38+,39+,40+,41+,44+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50251489 (CHEMBL481089 | butyl 5-isobutyl-3-(4-(isopropylcar...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)NC(C)C Show InChI InChI=1S/C23H32N2O5S2/c1-6-7-12-30-23(27)25-32(28,29)22-20(14-19(31-22)13-15(2)3)17-8-10-18(11-9-17)21(26)24-16(4)5/h8-11,14-16H,6-7,12-13H2,1-5H3,(H,24,26)(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50049189 (3-[4-(2-Ethyl-57-dimethyl-imidazo[45-b]pyridin-3-y...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1 Show InChI InChI=1S/C30H38N4O4S2/c1-7-9-14-38-30(35)33-40(36,37)29-25(17-24(39-29)15-19(3)4)23-12-10-22(11-13-23)18-34-26(8-2)32-27-20(5)16-21(6)31-28(27)34/h10-13,16-17,19H,7-9,14-15,18H2,1-6H3,(H,33,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at Angiotensin II receptor, type 2 in pig uterus myometrial membranes by [125I]-Ang II displacement.				J Med Chem 47: 1536-46 (2004) Article DOI: 10.1021/jm031031i BindingDB Entry DOI: 10.7270/Q2NS0TBV
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50168424 ((3S)-3-amino-3-{[(1S)-1-{[(2S)-4-({[(2S)-1-[(2S)-2...) Show SMILES N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc1cccc2CN(CC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc3ccccc3)C(O)=O)C(=O)[C@H](Cc3ccc(O)cc3)Nc12 Show InChI InChI=1S/C48H59N13O11/c49-32(22-40(64)65)42(66)58-34(11-5-17-53-48(50)51)43(67)57-33-10-4-9-29-24-60(45(69)35(56-41(29)33)19-28-13-15-31(62)16-14-28)25-39(63)55-36(21-30-23-52-26-54-30)46(70)61-18-6-12-38(61)44(68)59-37(47(71)72)20-27-7-2-1-3-8-27/h1-4,7-10,13-16,23,26,32,34-38,56,62H,5-6,11-12,17-22,24-25,49H2,(H,52,54)(H,55,63)(H,57,67)(H,58,66)(H,59,68)(H,64,65)(H,71,72)(H4,50,51,53)/t32-,34-,35-,36-,37-,38-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321064 (CHEMBL1165175 | N-Butyloxycarbonyl-3-[4-(1-methyl-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)c1nccn1C Show InChI InChI=1S/C24H29N3O5S2/c1-5-6-13-32-24(29)26-34(30,31)23-20(15-19(33-23)14-16(2)3)17-7-9-18(10-8-17)21(28)22-25-11-12-27(22)4/h7-12,15-16H,5-6,13-14H2,1-4H3,(H,26,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50139787 ((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-4-({[(2S)-...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(=O)Nc1ccc2N[C@@H](Cc3ccc(O)cc3)C(=O)N(CC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc3ccccc3)C(O)=O)Cc2c1 Show InChI InChI=1S/C53H68N14O12/c1-29(2)45(65-47(73)38(10-6-18-58-53(55)56)63-46(72)36(54)24-44(70)71)49(75)60-33-14-17-37-32(22-33)26-66(50(76)39(61-37)20-31-12-15-35(68)16-13-31)27-43(69)62-40(23-34-25-57-28-59-34)51(77)67-19-7-11-42(67)48(74)64-41(52(78)79)21-30-8-4-3-5-9-30/h3-5,8-9,12-17,22,25,28-29,36,38-42,45,61,68H,6-7,10-11,18-21,23-24,26-27,54H2,1-2H3,(H,57,59)(H,60,75)(H,62,69)(H,63,72)(H,64,74)(H,65,73)(H,70,71)(H,78,79)(H4,55,56,58)/t36-,38-,39-,40-,41-,42-,45-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity for Angiotensin II receptor type 2 using [125I]- Ang II in pig uterus myometrium				J Med Chem 47: 859-70 (2004) Article DOI: 10.1021/jm030921v BindingDB Entry DOI: 10.7270/Q2736RNQ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50251488 (CHEMBL521093 | N-Butoxycarbonyl-3-[4-(N,N-diethylc...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)N(CC)CC Show InChI InChI=1S/C24H34N2O5S2/c1-6-9-14-31-24(28)25-33(29,30)23-21(16-20(32-23)15-17(4)5)18-10-12-19(13-11-18)22(27)26(7-2)8-3/h10-13,16-17H,6-9,14-15H2,1-5H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50139787 ((3S)-3-amino-3-{[(1S)-1-{[(1S)-1-{[(2S)-4-({[(2S)-...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(=O)Nc1ccc2N[C@@H](Cc3ccc(O)cc3)C(=O)N(CC(=O)N[C@@H](Cc3cnc[nH]3)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc3ccccc3)C(O)=O)Cc2c1 Show InChI InChI=1S/C53H68N14O12/c1-29(2)45(65-47(73)38(10-6-18-58-53(55)56)63-46(72)36(54)24-44(70)71)49(75)60-33-14-17-37-32(22-33)26-66(50(76)39(61-37)20-31-12-15-35(68)16-13-31)27-43(69)62-40(23-34-25-57-28-59-34)51(77)67-19-7-11-42(67)48(74)64-41(52(78)79)21-30-8-4-3-5-9-30/h3-5,8-9,12-17,22,25,28-29,36,38-42,45,61,68H,6-7,10-11,18-21,23-24,26-27,54H2,1-2H3,(H,57,59)(H,60,75)(H,62,69)(H,63,72)(H,64,74)(H,65,73)(H,70,71)(H,78,79)(H4,55,56,58)/t36-,38-,39-,40-,41-,42-,45-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from angiotensin II receptor type 2 in pig uterus myometrium				J Med Chem 48: 4009-24 (2005) Article DOI: 10.1021/jm0491492 BindingDB Entry DOI: 10.7270/Q2BR8SZD
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321083 (CHEMBL1164113 | N-Butyloxycarbonyl-3-[4-(thiazole-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cc2nccs2)cc1 Show InChI InChI=1S/C23H28N2O4S3/c1-4-5-11-29-23(26)25-32(27,28)22-20(15-19(31-22)13-16(2)3)18-8-6-17(7-9-18)14-21-24-10-12-30-21/h6-10,12,15-16H,4-5,11,13-14H2,1-3H3,(H,25,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Sus scrofa)	BDBM50251537 (CHEMBL479399 | butyl 5-isobutyl-3-(4-(piperidine-1...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)N1CCCCC1 Show InChI InChI=1S/C25H34N2O5S2/c1-4-5-15-32-25(29)26-34(30,31)24-22(17-21(33-24)16-18(2)3)19-9-11-20(12-10-19)23(28)27-13-7-6-8-14-27/h9-12,17-18H,4-8,13-16H2,1-3H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125]Ang2 from AT2 receptor in pig uterus membrane				Bioorg Med Chem 16: 6841-9 (2008) Article DOI: 10.1016/j.bmc.2008.05.066 BindingDB Entry DOI: 10.7270/Q22F7N7C
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321067 (CHEMBL1165261 | N-Butyloxycarbonyl-3-[4-(2-methyl-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(cc1)C(=O)c1ccnn1C Show InChI InChI=1S/C24H29N3O5S2/c1-5-6-13-32-24(29)26-34(30,31)23-20(15-19(33-23)14-16(2)3)17-7-9-18(10-8-17)22(28)21-11-12-25-27(21)4/h7-12,15-16H,5-6,13-14H2,1-4H3,(H,26,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321074 (CHEMBL1164870 | N-Butyloxycarbonyl-3-[4-(2-oxo-pyr...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2CCCC2=O)cc1 Show InChI InChI=1S/C24H32N2O5S2/c1-4-5-13-31-24(28)25-33(29,30)23-21(15-20(32-23)14-17(2)3)19-10-8-18(9-11-19)16-26-12-6-7-22(26)27/h8-11,15,17H,4-7,12-14,16H2,1-3H3,(H,25,28)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321078 (CHEMBL1164104 | N-Butyloxycarbonyl-3-[4-(3,4,4-tri...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2C(=O)N(C)C(C)(C)C2=O)cc1 Show InChI InChI=1S/C26H35N3O6S2/c1-7-8-13-35-24(31)27-37(33,34)22-21(15-20(36-22)14-17(2)3)19-11-9-18(10-12-19)16-29-23(30)26(4,5)28(6)25(29)32/h9-12,15,17H,7-8,13-14,16H2,1-6H3,(H,27,31)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50321084 (CHEMBL1164531 | N-Butyloxycarbonyl-3-(4-oxazol-2-y...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cc2ncco2)cc1 Show InChI InChI=1S/C23H28N2O5S2/c1-4-5-11-30-23(26)25-32(27,28)22-20(15-19(31-22)13-16(2)3)18-8-6-17(7-9-18)14-21-24-10-12-29-21/h6-10,12,15-16H,4-5,11,13-14H2,1-3H3,(H,25,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199318 (CHEMBL384462 | N-(N-butyl-methylaminocarbonyl)-3-(...) Show SMILES CCCCN(C)C(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C24H32N4O3S2/c1-5-6-12-27(4)24(29)26-33(30,31)23-22(15-21(32-23)14-18(2)3)20-9-7-19(8-10-20)16-28-13-11-25-17-28/h7-11,13,15,17-18H,5-6,12,14,16H2,1-4H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50141044 (CHEMBL291124 | N-Butyloxycarbonyl-5-isobutyl-3-{4-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2c(CCC)nc3ccc(cc3c2=O)N(CC)C(C)=O)cc1 Show InChI InChI=1S/C35H44N4O6S2/c1-7-10-18-45-35(42)37-47(43,44)34-29(21-28(46-34)19-23(4)5)26-14-12-25(13-15-26)22-39-32(11-8-2)36-31-17-16-27(20-30(31)33(39)41)38(9-3)24(6)40/h12-17,20-21,23H,7-11,18-19,22H2,1-6H3,(H,37,42)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at Angiotensin II receptor, type 2 in pig uterus myometrial membranes by [125I]-Ang II displacement.				J Med Chem 47: 1536-46 (2004) Article DOI: 10.1021/jm031031i BindingDB Entry DOI: 10.7270/Q2NS0TBV
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50195698 ((3S)-3-amino-3-{[(1S)-1-{[(2S)-2-[(2S)-butan-2-yl]...) Show SMILES CC[C@H](C)[C@@H]1Nc2c(Cc3ccc(O)cc3)cc(NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)cc2CN(CC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N2CCC[C@H]2C(=O)N[C@@H](Cc2ccccc2)C(O)=O)C1=O |wU:32.33,4.3,2.2,63.66,wD:21.29,46.47,59.63,(14.77,-5.6,;13.95,-6.91,;12.41,-6.86,;11.69,-5.5,;11.6,-8.16,;10.09,-7.83,;8.87,-8.79,;7.53,-8.02,;7.53,-6.48,;6.19,-5.71,;6.2,-4.17,;4.85,-3.41,;3.53,-4.18,;2.19,-3.41,;3.54,-5.73,;4.87,-6.49,;6.21,-8.79,;6.21,-10.32,;4.87,-11.09,;3.54,-10.32,;3.54,-8.78,;2.2,-11.09,;2.2,-12.63,;3.54,-13.4,;3.54,-14.94,;4.87,-15.71,;4.87,-17.25,;6.21,-18.02,;3.54,-18.02,;.87,-10.32,;-.46,-11.09,;-.46,-12.63,;-1.8,-10.32,;-3.13,-11.09,;-1.8,-8.78,;-3.13,-8.01,;-4.46,-8.78,;-3.13,-6.47,;7.54,-11.1,;8.87,-10.33,;10.08,-11.31,;11.6,-10.96,;12.55,-12.16,;14.09,-12.11,;14.92,-13.39,;14.81,-10.72,;16.34,-10.65,;17.53,-11.64,;17.47,-13.18,;18.76,-14.05,;18.26,-15.53,;16.72,-15.53,;16.25,-14.07,;17.09,-9.31,;16.31,-8,;18.62,-9.3,;19.15,-10.73,;20.69,-10.73,;21.12,-9.23,;19.81,-8.37,;19.05,-7.02,;17.51,-7,;19.83,-5.69,;19.11,-4.35,;17.56,-4.3,;16.83,-2.94,;17.63,-1.63,;16.91,-.28,;15.37,-.23,;14.55,-1.54,;15.29,-2.89,;19.9,-3.03,;19.17,-1.68,;21.45,-3.07,;12.27,-9.56,;13.81,-9.56,)| Show InChI InChI=1S/C52H67N13O11/c1-3-29(2)44-50(74)64(27-42(67)60-39(23-35-25-56-28-58-35)49(73)65-18-8-12-41(65)48(72)62-40(51(75)76)20-30-9-5-4-6-10-30)26-33-22-34(21-32(45(33)63-44)19-31-13-15-36(66)16-14-31)59-47(71)38(11-7-17-57-52(54)55)61-46(70)37(53)24-43(68)69/h4-6,9-10,13-16,21-22,25,28-29,37-41,44,63,66H,3,7-8,11-12,17-20,23-24,26-27,53H2,1-2H3,(H,56,58)(H,59,71)(H,60,67)(H,61,70)(H,62,72)(H,68,69)(H,75,76)(H4,54,55,57)/t29-,37-,38-,39-,40-,41-,44-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus myometrium				J Med Chem 49: 6133-7 (2006) Article DOI: 10.1021/jm051222g BindingDB Entry DOI: 10.7270/Q28P619Q
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199312 (CHEMBL217249 | N-butyloxycarbonyl-3-(4-imidazol-1-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCCC)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C23H29N3O4S2/c1-3-5-7-20-15-21(19-10-8-18(9-11-19)16-26-13-12-24-17-26)22(31-20)32(28,29)25-23(27)30-14-6-4-2/h8-13,15,17H,3-7,14,16H2,1-2H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199321 (CHEMBL214592 | N-butyloxycarbonyl-2-(4-imidazol-1-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccc(CCCC)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C25H31N3O4S/c1-3-5-7-20-10-13-24(33(30,31)27-25(29)32-16-6-4-2)23(17-20)22-11-8-21(9-12-22)18-28-15-14-26-19-28/h8-15,17,19H,3-7,16,18H2,1-2H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199332 (CHEMBL216688 | N-butyloxycarbonyl-3-(4-imidazol-1-...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CCC)cc1-c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C22H27N3O4S2/c1-3-5-13-29-22(26)24-31(27,28)21-20(14-19(30-21)6-4-2)18-9-7-17(8-10-18)15-25-12-11-23-16-25/h7-12,14,16H,3-6,13,15H2,1-2H3,(H,24,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]Ang2 from AT2 receptor in pig uterus membrane				J Med Chem 49: 7160-8 (2006) Article DOI: 10.1021/jm0606185 BindingDB Entry DOI: 10.7270/Q21C1WHK
					More data for this Ligand-Target Pair

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